A device for storing, incubating or manipulating biological samples, in particular incubating device or shaking device, comprising a sample chamber, an irradiation chamber, and a holder with a UV light source, wherein a sidewall of the irradiation chamber comprises a first mounting member and wherein the holder comprises a second mounting member configured to interact with the first mounting member for pre-mounting the holder to the sidewall.

Provided is a cell culture sheet. A cell culture sheet according to an embodiment of the present invention includes: a fiber web which has a 3-dimensional network structure formed through the accumulation of support fibers having an average diameter of at most 1.5 μm, and has a basis weight of 1 to 15 g/m.sup.2; and a functional coating layer which is coated on the support fibers exposed on at least one surface of the fiber web, and has a function of promoting one or more of the adhesion, movement, proliferation, and differentiation of cells. Accordingly, cell adhesion is improved due to the large specific surface area and the surface morphology suitable for cells, and the adhered cells are stably supported. Moreover, the cells can be cultured at high density at a high culture efficiency, and can be cultured and recovered without agglomeration caused by forming a thin film.

A bioreactor includes a culture medium vessel housing culture medium. The culture medium vessel further includes a first side surface including a first transparent optical window; and a second side surface parallel to the first surface and including one or more sensor adapters to fix optical sensors. A cell retention vessel is disposed underneath and connected to the culture medium vessel, the cell retention vessel housing biological cells and having: a top surface that intersects a base of the culture medium vessel, and a second transparent optical window indented into the top surface at a first corner of the top surface. A semipermeable membrane is disposed at a bottom of the cell retention vessel, and a frame comprising a grid is disposed underneath the semipermeable membrane.

A cell screening device including a bottom plate, a cell placement membrane, a pair of fluid injection parts, and a flow channel, the flow channel being formed between the bottom plate and the cell placement membrane and extending in such a manner that the flow channel end parts respectively reach the fluid injection parts. In the cell placement membrane, a plurality of wells, each having a size capable of housing a single cell, and through holes are formed. In the back side of each lid, i.e., the ceiling face of the flow channel end part, a debubbling surface, which rises in an inclined or step-like manner as getting closer to a fluid injection hole, is formed.

According to the present invention, an initial-stage test apparatus-culturing condition (parameter set) is determined (22) on the basis of a manual culturing condition (26) for a specific cell. Multiple apparatus-culturing tests (20) are run in accordance with multiple test apparatus-culturing conditions, including the initial-stage test apparatus-culturing condition. A test apparatus-culturing condition at the time point when the result of an apparatus-culturing test satisfies requirement specifications is set (40) in a culturing apparatus as a setting apparatus-culturing condition, and the culturing apparatus is set up by using said setting apparatus-culturing condition.

A computer-controlled system designed for multi organ decellularization uses continuous organ perfusion for fast, efficient and reproducible organ scaffold preparation under sterile conditions, allowing organ storage for ready organ regeneration. A single organ version is designed to be used for a single organ recellularization using cell, stem cell and autologous cell of organ receiver solutions for minimal or no immunogenic response, mimicking endogenous organ preparation for patients needing transplantation.

The invention concerns a frame (1) for holding a plurality of filtration assemblies (100) and a testing unit (10) for microbiological testing. The frame (1) for holding the plurality of filtration assemblies (100) comprises an array of supports (5) each configured to receive and support one of the filtration assemblies (100) on a common support plane (2), and connection means (6) provided on the periphery (7) of the frame (1) and configured to releasably connect, by a form-locking engagement, a further frame (1) such that the common support planes (2) of the connected frames (1) are contiguous. Further, the testing unit (10) comprises at least one frame (1) packed in a bag (20) in pre-sterilized condition.

A bench top incubator is described. The bench top incubator includes a first tray stack designed to retain microscope slides in a plurality of slide trays and a second tray stack designed to retain multi-well plates in a plurality of plate trays. The incubator is relatively simple and small in design and can be conveniently located to carry out temperature processing of biological samples such as fixed cells and tissues, biological fluids, and so forth.

An apparatus that configures a culture plate for precisely assigning coordinates to a selected colony by assigning fiducials to the culture plate using simple mechanical techniques. The fiducials correspond to the plate center and the center of a barcode label applied to the side of the culture plate by the apparatus. The apparatus then deploys mechanisms to apply coordinates to colonies identified by the user relative to the fiducials. One such mechanism is a webcam pointed at the culture plate that allows a technician to mark the colonies on a display using a computer mouse or equivalent cursor. Another mechanism deploys a laser pointer directed at the colony wherein the apparatus assigns coordinates to the location of the colony onto which the laser pointer is directed. In a third mechanism, the user views the surface of the culture plate through a viewfinder and manually registers coordinates when the view finder cross hairs are over a target colony. The selected colonies are assigned precise coordinates with reference to the two fiducials. Software is provided such that pixels in the image of the culture plate correspond to the coordinates of the culture dish relative to the fiducials.

Filter holders and membranes are provided that can be included within a bioreactor bag system. The filter holders and membranes include features that abut the bottom of the filter membrane and prevent or reduce sagging of the porous filter region during use.