C12M23/50

NOVEL PLASMA INDUCED MUTATION BREEDING DEVICE
20170267963 · 2017-09-21 ·

The invention relates to a novel plasma induced mutation breeding device which comprises: a sample treatment system including a sterile working compartment free of bioactive contaminant; a plasma generator; a radio frequency (RF) power module connected with the plasma generator; a cooling system for cooling the plasma generator; a detection system including a gas flow controller for controlling the gas flow which generates the plasma jet and a temperature sensor for detecting the temperature of the jet emitted by the plasma generator; and a control system with an operation panel and a controller for controlling the operation of the mutation breeding device, wherein the controller is connected with the RF power module, gas flow controller, temperature sensor, cooling system as well as the operation panel, respectively, and said plasma generator stably emits the plasma jet at 37±3° C. during the biological sample processing.

Integrated organ and tissue printing methods, system and apparatus

A method of making an organ or tissue comprises: (a) providing a first dispenser containing a structural support polymer and a second dispenser containing a live cell-containing composition; (b) depositing a layer on said support from said first and second dispenser, said layer comprising a structural support polymer and said cell-containing composition; and then (c) iteratively repeating said depositing step a plurality of times to form a plurality of layers one on another, with separate and discrete regions in each of said layers comprising one or the other of said support polymer or said cell-containing composition, to thereby produce provide a composite three dimensional structure containing both structural support regions and cell-containing regions. Apparatus for carrying out the method and composite products produced by the method are also described.

AUTOMATED, MULTIFUNCTIONAL, ENGINEERED CARDIAC TISSUE CULTURE AND TESTING BIOREACTOR SYSTEM
20170260488 · 2017-09-14 ·

An improved tissue engineering bioreactor and testing platform has been designed that integrates multiple testing and stimulation capabilities. The system allows for growth of multiple tissue strips in parallel with mechanical and electrical stimulation, media perfusion, and the automated monitoring of contractile force and extracellular electrical activity. The system is designed to be low-cost and scalable, to provide for high-content, biofidelic, non-destructive testing of engineered muscle tissue performance that is conventionally measured using muscle-bath systems.

CELL CULTURE APPARATUS

A cell culture apparatus including cell culture units U and a measurement part (5). The measurement part (5) is provided with an imaging part (51) and is disposed so as to be capable of moving up and down between a back panel part (21) of a casing (2) and a culture container accommodating shelf (32). When the measurement unit (5) reaches a measurement position of each cell culture unit U which is a measurement subject, the culture container accommodating shelf (32) slides toward the measurement unit (5) so that portions to be measured of culture containers U20, U30 in each cell culture unit U come in an imaging range of the imaging part (51).

BIOPROCESSING SYSTEM AND TUBING AND COMPONENT MANAGEMENT APPARATUS FOR A BIOPROCESSING SYSTEM

A bioreactor vessel includes a bottom, a peripheral sidewall, the bottom and the peripheral sidewall defining an interior space for receiving a flexible bioprocessing bag, a recess in the bottom for receiving a base plate of the flexible bioprocessing bag, and a locking mechanism configured to retain the base plate in the recess.

LAB-WARE AND HANDLING SYSTEM TO HANDLE LAB-WARE IN A CELL CULTURE PROCESS

A set of lab-ware for a cell culture process includes two or more components selected from: A plate comprising one or more processing wells in a regular arrangement; a plate suitable for holding or holding pipette tips in a regular arrangement; a plate comprising compartments individually holding or suitable for individually holding vials in a regular arrangement; a plate comprising two or more substantially rectangular wells in a regular arrangement; a lidded bottle for bulk supply of a solution or cell culture medium; a plate comprising one or more compartments for holding reagent bottles, two or more of the compartments being in a regular arrangement; a plate having a single well; a plate comprising one or more storage wells holding reagents, being sealed by a foil and/or covered by a lid. All of the two or more components have a uniform footprint. A robotic handling device manipulates the lab-ware.

ROBOTS AND ROBOTIC SYSTEMS FOR FLUID HANDLING AND TRANSPORT OF BIODEVICES AND APPLICATIONS OF SAME
20220229441 · 2022-07-21 ·

A robot for transporting a biodevice from one place to another place, comprising a body for carrying the biodevice; a driving assembly for driving the body in omnidirectional motion; a sensing unit for sensing at least a position and orientation of the body; and a control unit coupled to the driving assembly and the sensing unit for generating one or more control signals based on at least the sensed position and orientation of the body to drive the driving assembly so as to move the body to a desired place and to arrive with the correct orientation.

Device for centering of petri dishes

A device for centering of petri dishes, where the petri dishes include a bottom container with a lateral surface and a lid with a lid diameter, including an elevator with an elevator axis and an elevator drive, and the conveyor includes concentrically along the elevator axis a frustoconical through-hole tapering downwards, and the elevator drive is built to move a substantially flat plate from a neutral position downwards into a first position, which is reached as soon as the petri dish rests with its weight on the inner surface of the through-hole, and the elevator drive is built to rotate the plate during a movement of the plate from the neutral position into the first position.

INCUBATOR AND METHOD OF OPERATING MICROFLUIDIC DEVICE
20210395656 · 2021-12-23 ·

There is provided an incubator including an accommodation space that is shielded from an external environment, an environmental control unit that controls an environment of the inside of the accommodation space, a power supply unit that is provided in the accommodation space and transmits electric power to a power supply target in a noncontact state, and a partition wall that is provided in the accommodation space and shields electromagnetic waves radiated from the power supply unit.

INCUBATOR AND STERILIZATION METHOD FOR THE SAME
20210395667 · 2021-12-23 ·

The present disclosure discloses an incubator, comprising: a housing defining an incubation chamber, and the incubation chamber is a sealable structure; a shaker located inside the incubation chamber; one or more vent panels, which are each provided with a plurality of vent openings, wherein the incubation chamber is divided into a first area and a second area by the vent panels and the housing, and the shaker is located inside the first area; and a blowing device, for guiding gas flow; wherein, gas in the incubation chamber is driven to circulate between the first area and the second area through cooperation of the vent panels, an inner wall of the housing and the blowing device.