A holding tool is configured to be used together with a container and a lid for the container to sandwich the container and the lid. The holding tool includes a base on which the container is placed, and a cover configured to cover the lid. The base and the cover each have an opening at a central portion and are configured to engage with each other to press and sandwich the container and the lid upward and downward.

A manufacturing article adapted for use in the production of pharmaceuticals comprising a tray comprising a base having a top surface; and a manifold extending from the top surface of the base, the manifold comprising a sidewall and an upper surface, the upper surface further comprising a channel, wherein, when viewed from the top surface, the base has an area, A.sub.B, the upper surface of the manifold has an area A.sub.M, and A.sub.B>A.sub.M, and wherein the base is adapted to support a plurality of vessels each adapted to contain a fluid.

The carriers that are available in the market don't maintain all the necessary parameters that I am mentioning in my invention. Many of them are: 1) Costly 2) Allow the transport of cells for short period of time 3) Are suitable for transporting certain type of cells 4) Don't include control for all the parameters that are required for the experiments 4) Need extra steps which can affect the experiment/organs and waste the time, efforts and money of the researchers. 5) Limit the researchers for using containers with certain sizes and materials.

Alternatively, the Mini-incubator carrier box in my invention is an economic transport system. It enables the researchers to fix different containers using clamps and screws and to transport the organs/samples/cells in any container for long period of time and long distance under optimized conditions without the need of extra steps/costs.

The present invention provides a simple culture device that is designed for manufacture and use in areas of limited resources. The device is useful for cell culture in such environments with limited resources because cells grow in paper just as they do in a culture dish. Also provided is a binding assay that employs an activatable dormant bacteriophage carrying a reporter gene to qualitatively or quantitatively detect the presence of a substance of interest in a sample.

An incubator (110, 140) for the reception of an individual sample carrier, a shelving system (100) for such incubators, a transport container for such incubators, as well as a modular system are suggested, wherein the incubators can be inserted and withdrawn (130) independently of one another, can be supplied with electricity, water and a gas via corresponding connections (150), and can communicate with a computer network via a wireless connection. Such a system reduces the risk of contamination or confusion in the lab and avoids interruptions in the monitoring and controlling of the environmental conditions in the respective incubators. These can rather independently maintain the most favourable environmental conditions for the respective samples, both during storage and also during a transport operation. The insertion and withdrawal of individual incubators from the shelving system does not, or only very briefly, interrupt the monitoring and control of the conditions in the interior of the incubators.

A portable incubator system integrated to a mobile phone providing a real-time tracking of samples and data flow is provided. The portable incubator system allowing cells to be cultured, reproduced and characterized in real-time without a need for a commercial incubator and a microscope-camera system installed within the portable incubator system.

A portable bioreactor is provided. The portable bioreactor may comprise: a frame unit; a cell culture unit which has one side mounted to the frame unit and in which a plurality of supports for cell culture are arranged, the cell culture unit being provided with an inlet, through which a medium supplied from the outside flows in, and an outlet, through which the medium inside the cell culture unit is discharged to the outside, a medium adjustment unit installed in the frame unit and storing therein a certain amount of medium for the cell culture; a circulation pump installed and fixed to the frame unit to circulate the medium stored in the medium adjustment unit; and a gas supply unit for supplying gas to the medium adjustment unit to maintain the medium stored in the medium adjustment unit at a constant pH.

The present disclosure is directed to portable bioreactors that allow the custom production of microbial cultures, and in some embodiments, the production of custom microbial biofilms. Also disclosed are portable bioreactor systems that are networked and capable of cooperative work in parallel.

Extracting healthy primary cells from animals or human (e.g. aborted fetuses) is one of the challenging methods in scientific laboratories. At the same time, it is needed to conduct experiments in many fields such as neuroscience, cell biology, developmental biology, transplantation, molecular biology. Trituration is one of the steps required for the extraction of primary cells. The conduction of this challenging process needs care as if it was not done properly, it can lead to cell death or low yield. There is need for an apparatus to conduct trituration with steady force and speed (flow rate), decrease the efforts and time of researcher and allow flexibility in choosing the speed, suspension's volume and number of trituration steps. The primary cells' triturator can achieve the aforementioned properties, help in increasing the number and quality of primary cells that survive in culture and lead to decrease in the costs of the experiment.

The embodiments disclose a portable and compact bioreactor for controlled cultivation of mycelium spores, including a bioreactor cartridge with an injection port configured to transfer predetermined nutrients and mycelium spores into the bioreactor cartridge for cultivation of the mycelium spores, a pressure relief valve, a heating element, an air pump, an agitator and a cloud control system configured to analyze empirical data related to cultivation of the mycelium spores to determine the predetermined speed, the predetermined parameters and the predetermined nutrients to produce specific harvest results and to make future automatic adjustments to the predetermined speed, the predetermined parameters and the predetermined nutrients based on the specific harvest results and a bioreactor cloud data app configured to remotely monitor settings of the bioreactor, to allow the user to adjust the settings and to receive recommended settings based on the analysis of the cloud control system.