Patent classifications
C12M29/06
PARALLEL AND INTERCONNECTED CELL CULTURE VESSEL SYSTEM
Embodiments relate to a unique design of a cell growth vessel stack system that provides for inter-communication of cell growth levels arranged in a parallel configuration so to facilitate environmental uniformity of the inter-connected growth surface tiers. The unique design also facilitates a fine-tuning of optimized gas and media flow to each cell growth level within the vessel stack. The unique architecture facilitates media refreshment at conveniently scheduled intervals and/or allows constant perfusion from a media reservoir that can be replenished without interrupting the cell proliferation rate. The perfusion rate, nutrient medium condition, CO2 content and osmolality can be controlled to optimize the desired cell proliferation rate, thereby improving cell quantity, quality, and viability.
Condenser Bag for Processing a Fluid
A condenser bag includes a body bounding a channel that extends between an inlet opening at a first end and an outlet opening at an opposing second end, the body being comprised of a polymeric film; an intake port bounding a port opening that extends therethrough, the intake port being directly physically secured to the first end of the body so that the port opening communicates with the channel of the body; and a tubular transfer line having a first end directly mechanically coupled with the body at a first location located between the inlet opening and the outlet opening so as to communicate with the channel and an opposing second end directly mechanically coupled to the intake port so as to communicate with the port opening thereof.
METHODS AND APPARATUS FOR HYDROGEN BASED BIOGAS UPGRADING
The present invention relates to an anaerobic process for biogas upgrading and hydrogen utilization comprising the use of acidic waste as co-substrate. In this process, H.sub.2 and CO.sub.2 will be converted to CH.sub.4, which will result in lower CO.sub.2 content in the biogas. The invention relates to both in situ and ex situ methods of biogas upgrading. The invention further relates to a bioreactor comprising hollow fiber membranes.
Condenser bag for processing a fluid
A condenser bag includes a body bounding a channel that extends between an inlet opening at a first end and an outlet opening at an opposing second end, the body being comprised of a polymeric film; an intake port bounding a port opening that extends therethrough, the intake port being directly physically secured to the first end of the body so that the port opening communicates with the channel of the body; and a tubular transfer line having a first end directly mechanically coupled with the body at a first location located between the inlet opening and the outlet opening so as to communicate with the channel and an opposing second end directly mechanically coupled to the intake port so as to communicate with the port opening thereof.
Bioreactor with integrated flue gas distribution
A system includes a photobioreactor that provides a channel configured to contain an algae slurry, a duct positioned adjacent the channel and configured to convey a gas, and a barrier separating the duct from the channel and providing one or more apertures to allow a portion of the gas to be injected into the algae slurry from the duct.
Method of forming a collapsible bag using a mold and mandrel
A bioreactor configured to contain a volume of liquid is provided. The bioreactor includes a collapsible bag able to contain the volume of liquid, a support structure surrounding and containing the collapsible bag, a first sparger connected to the collapsible bag, the first sparger having a first aperture size, and a second sparger connected to the collapsible bag, the second sparger having a second aperture size that is different from the first aperture size.
ASSEMBLY SYSTEM FOR A SMART TANK FOR A BIO-PHARMA PROCESS
The present invention relates to an assembly system for assembling a modular smart tank, a method for assembling a modular smart tank, a mobile storage means and an assembly bag. The assembly system comprises at least one mobile storage means for storing components of at least one smart tank, an assembly room, wherein the assembly room is adapted to provide clean room conditions and wherein the assembly room is configured to allow assembly of at least one smart tank within the assembly room from the components stored in the mobile storage means, and a manipulator, being adapted to automatically assemble the smart tank within the assembly room.
SINGLE-CELL SCREENING DEVICE, SCREENING ASSEMBLY, SCREENING METHOD, AND USE THEREOF
A single-cell screening device, a screening assembly, a screening method, and use thereof. The single-cell screening device includes a body, a plurality of spray holes, heating portions, and a flow channel. The spray holes are located in the body, the heating portions are located in the spray holes and used for heating a liquid entering the spray holes to generate bubbles so as to spray out cells. The flow channel is located in the body and extends to the spray holes according to a preset path, so as to deliver a cell suspension into the spray holes. The single-cell screening device of the present disclosure has a simple design and is easy to fabricate. Cell printing (spraying) using the screening assembly of the present disclosure has a much higher cell printing speed than conventional methods, allowing for a rapid cell sorting process.
Impeller and Sparger Assemblies for a Bioprocessing System
A sparger assembly (700) for a bioprocessing system includes a base plate (710) and at least one aeration manifold (712, 714) removably connected to tire base plate. Each aeration manifold includes at least one inlet for receiving a gas and a plurality of gas outlet openings for delivering tire gas to a fluid within the bioprocessing system. An impeller assembly (740) fora bioprocessing system includes a hub and at least one blade (742) operatively connected to the hub. The at least one blade includes a first portion connected to the hub and extending generally vertically, and a second portion extending at an upward angle from tire first portion.
Condenser systems for processing a fluid
A condenser system includes a collapsible container bag bounding a compartment and having an upper end and an opposing lower end, the container bag being formed of a polymeric film and being adapted to hold a fluid. A condenser bag is formed of a polymeric film and bounds a channel that extends between a first end and an opposing second end, the first end of the condenser bag being fluid coupled with the upper end of the container bag. A tubular transfer line has a first end coupled with the condenser bag at a first location so as to communicate with the channel and an opposing second end coupled with the condenser bag at a second location located between the container bag and the first location so as to communicate with the channel.