The specification describes devices, methods, and kits for mincing biological tissue. The method includes conforming biological tissue to having about uniform cross-sectional area planes along its length, and cutting the biological tissue. The conforming and cutting is performed cooperatively to control the size of the minced biological tissue. The device is suitable for use with the method.

The present invention relates to a device and a method for FIG. 2 treating fat cells taken from a patient and intended for a transplant. More specifically, it relates to a device and a method by suctioning which makes it possible to separate the viable fat cells from the residues and elements which are not transplantable. The device is a device for treating adipose tissues (G) connected to a suctioning means (M), consisting of a sealed treatment chamber (A) comprising a means for connection (17) to said suctioning means (M), a means for inlet (13) of said adipose tissues before treatment, a filtration means (3) and at least one means for outlet (20) of said adipose tissues (G) after treatment, said filtration means (3) comprising a conically shaped external wall (3 1, 3) comprising a narrow base (55) attached to an impeller (25) and an internal sieving means (30) connected to the output means (20), said impeller (25) being subjected to the air pressure reduction created by the suctioning means (M) and constituting a rotary mechanical actuating means for actuating said filtration means (3).

A disaggregation system includes a console, the console including a housing, a pod holder plate, a motive applicator mounted in the housing and configured to move the pod holder plate. The system further includes a sample pod configured for holding tissue to be disaggregated, where the sample pod includes a collector component configured for mounting to the pod holder plate; a tissue holder sleeve configured for holding tissue to be disaggregated; and a disaggregation screen. Tissue can be disposed in the sample pod, the sample pod configured to be mounted on the pod holder plate of the console, and when the motive applicator moves the pod holder plate with the pod thereon, tissue in the sample pod configured to be disaggregated into cells.

An improved dry grind system and method for producing a sugar stream from grains or similar carbohydrate sources and/or residues, such as for biofuel production. In particular, a sugar/carbohydrate stream, which includes a desired Dextrose Equivalent (DE) where DE describes the degree of conversion of starch to dextrose (aka glucose) and/or has had removed therefrom an undesirable amount of unfermentable components, can be produced after saccharification and prior to fermentation (or other sugar conversion process), with such sugar stream being available for biofuel production, e.g., alcohol production, or other processes. In addition, the systems and methods also can involve the removal of certain grain components, e.g., corn kernel components, including protein, oil and/or fiber, prior to fermentation or other conversion systems. In other words, sugar stream production and/or grain component separation occurs on the front end of the system and method.

Non-enzymatic method and milling device for preparing therapeutic cells from adipose tissue comprising: continuously feeding the adipose tissue to the milling device (2); mechanically separating the cells or cell aggregates from adipose tissue moving through the milling device (2) by means of a multiplicity of blades (19) of a rotor (10), wherein the blades (19) are arranged in a spaced arrangement with respect to the overall direction of flow and the blades (19) are moving about an axis of rotation (18), wherein the axis of rotation (18) is provided essentially parallel to said overall direction of flow; continuously withdrawing the processed tissue comprising the separated cells from the milling device (2).

A centrifugal piston according to an embodiment comprises: a piston body defining a path which extends from the front of the piston to the rear of the piston, and through which substances at the front of the piston can move to the rear of the piston; and a valve disposed on the path and configured to selectively open or block the path, wherein, during centrifugation in which centrifugal force acts on the piston, the substances at the front of the piston are centrifuged while the valve is blocking the path, and, when an external force is applied to the piston while the centrifugal force does not act on the piston, the valve moves freely relative to the piston body, and when the valve opens the path, at least a portion of the substances at the front of the piston can move to the rear of the piston.

A tissue processing chamber is disclosed. The tissue processing chamber includes at least one rotary blade housed within a tissue chamber and a drive shaft coupled to the rotary blades. Rotation of the drive shaft rotates the rotary blades and presses a tissue sample through a screen adjacent to the at least one rotary blade, wherein rotation of the at least one rotary blade presses processed tissue through the screen. The tissue processing device also includes a collection chamber coupled to the tissue chamber configured to collect the processed tissue.

Harvested adipose tissue is processed in a single-use portable processing container to prepare a centrifuges pellet phase of stromal vascular fraction concentrate, which is selectively removed and disposed in a syringe dispersed in a dispersion medium to prepare an osteoarthritis treatment product.

Disclosed are methods and devices for processing lipoaspirate that include mechanically-processing harvested lipoaspirate in a liposuction filter canister. In some embodiments, the devices are liposuction devices that include a lipoaspirate processing unit for mechanically-processing lipoaspirate. The mechanical processing reduces the average size of adipose tissue pieces in the lipoaspirate without substantially rupturing lipocytes therein.

A biological material manufacturing device according to an embodiment of the inventive concept includes a main body and a head unit that is rotatable on the main body. The main body includes a main groove and a first container groove connected to the main groove. The head unit includes a pillar provided in the main groove and a protruding part that protrudes from the pillar.