Patent classifications
C12M47/12
DEVICE FOR MANUFACTURING ORGANIC SUBSTANCE, AND GAS PROCESSING SYSTEM
Provided are a device for producing an organic substance capable of preventing foaming in a purification section to purify an organic substance and obtaining the organic substance with high yield and a gas treatment system having such a device for producing an organic substance. A device for producing an organic substance, includes: a fermenter 4 configured to generate an organic substance from gas by fermenting action of a microorganism; a separation section 5 configured to separate a discharge fluid discharged from the fermenter 4 into a first liquid containing a solid substance containing the microorganism and the organic substance and a second liquid containing the organic substance and a less content of the solid substance than that in the first liquid; an evaporation section 6 configured to evaporate a liquid component containing the organic substance from the first liquid; and a purification section 7 configured to purify the organic substance from the second liquid and the liquid component vaporized in the evaporation section 6.
SOLID-LIQUID BOUNDARY DETECTION DEVICE AND PRE-PROCESSING DEVICE PROVIDED WITH SAME
A solid-liquid boundary detection device 20 is a device for detecting a boundary 141 between a solid and a liquid in a test tube 14, and includes a surface illumination 21, an imaging unit 22, and a boundary detection processor 31. The surface illumination 21 illuminates the test tube 14 from outside. The imaging unit 22 is arranged on an opposite side of the test tube 14 from the surface illumination 21, and captures an image including the boundary 141. The boundary detection processor 31 detects the boundary 141 from the image captured by the imaging unit 22.
Systems and methods for medical device control
Systems, devices, and methods of the present disclosure assist with management of tubes and hoses during surgical procedures. The systems, devices, and methods provide for the proper opening and closing of tubes to facilitate performance of steps in a surgical procedure. Systems, devices, and methods of the present disclosure control fluid delivery to and from a medical device, including devices for tissue processing and cleaning.
Methods And Compositions For Purification Or Isolation Of Microvesicles And Exosomes
The invention provides methods and compositions for the isolation or extraction of exosomes or microvesicles. The methods and compositions may involve providing a device including exosome-binding ligands in the form of anionic or electron-rich groups arranged on a substrate surface. The methods and compositions may involve providing a device including a substrate having a surface, with a plurality of polymers attached to the substrate and exosome-binding ligands in the form of anionic or electron-rich groups arranged on the plurality of polymers.
SPHERE CULTURE MEMBER, CULTURE CONTAINER, METHOD FOR PROCESSING PERFORATED MEMBER, AND CLEANING CONTAINER
It is possible to efficiently replace a medium, clean spheres, and arrange spheres at regular intervals in the formation of spheres. A member is capable of capturing spheres, the member having a first surface and a second surface on an opposite side of the first surface, and having a plurality of recesses; the recess having an opening formed in the first surface, and one microhole being formed for each opening in the second surface; a circle or inscribed circle of the opening having a diameter a of 50 μm or more and 1 mm or less, a circle or inscribed circle of the microhole having a diameter b of 1 μm or more and less than 200 μm, and a and b satisfying a>b.
MAGNETIC BEAD PURIFICATION SYSTEM
The present invention provides a magnetic bead purification system, including: a housing; a liquid path treatment system provided inside the housing, the liquid path treatment system being connectable to a reagent barrel and a waste liquid barrel; a sample addition needle group connected to the liquid path treatment system, the sample addition needle group being movable within the housing and connected to the liquid path treatment system, so as to receive a reagent from the liquid path treatment system or to discharge a waste liquid to the liquid path treatment system; a purification magnetic separation system, including a magnetic element, the purification magnetic separation system being controllable to apply a lateral magnetic force to a purification treatment position inside the housing or stop the application of the magnetic force by the magnetic element; and a purification station system movable between a purification treatment position inside the housing and a loading position outside the housing, the purification station system being adapted to load a container. The magnetic bead purification system of the present invention can easily achieve large capacity sample treatment.
AMMONIA ADSORBENT AND METHOD FOR REMOVING AMMONIA
The ammonia adsorbent contains at least one substance selected from the group consisting of L-type zeolite, ferrierite, ZSM-5 type zeolite, strongly acidic cation exchange resin and Prussian blue type complex.
FILTRATION FILTER
A filtration filter according to the present invention includes a surface layer composed mainly of Pd, a base material inside the surface layer and composed mainly of a PdNi alloy, and an intermediate layer between the surface layer and the base material, wherein the intermediate layer is composed mainly of a PdNi alloy in which a Pd:Ni ratio changes from a surface layer side toward a base material side.
METHODS TO INCORPORATE MACHINE LEARNING ANALYTICS FOR OPTIMIZING PROTEIN PURITY, POTENCY AND QUALITY IN AN ON-DEMAND PRODUCTION SYSTEM FOR POINT-OF-CARE DELIVERY
The present invention relates to cell free protein manufacturing, and more particularly, for integrating machine learning into a portable cell-free bioprocessing system for producing proteins with increased and consistent purity, potency and quality wherein such proteins are prepared on-demand and for point-of-care delivery.
SYSTEMS, METHODS, AND DEVICES FOR AUTOMATED NUCLEIC ACID AND PROTEIN ISOLATION
- Alexander Vlassov ,
- Timothy BARTA ,
- Justin INSLEE ,
- Ethan GENTERT ,
- Robert SMITH ,
- Sara THIELE ,
- Carolyn Adams ,
- Kraig KRUGER ,
- Robert Schneider ,
- Wade LUKIANOW ,
- Jay GRECO ,
- Jason JONES ,
- David CERRONE ,
- Sumonto GHOSH ,
- Brian VAJDA ,
- Andrew BASTA ,
- Allan EVANS ,
- Christopher CROWLEY ,
- Robert Setterquist ,
- Anne Cox ,
- Mark MAYERNICK
Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.