A yeast strain producing glutathione (GSH) and aldehyde dehydrogenase, and more specifically, the yeast strains Saccharomyces cerevisiae Kwon P-1 KCTC13925BP, Saccharomyces cerevisiae Kwon P-2 KCTC14122BP, and Saccharomyces cerevisiae Kwon P-3 KCTC14123BP, which produce both glutathione and aldehyde dehydrogenase.

Manipulation of male fertility in a polyploid species requires attention to the interaction of male-fertility alleles of multiple genomes. In hexaploid wheat, single-genome heterozygotes for Ms26 provide differential levels of male fertility across genomes. Hexaploid wheat homozygous for mutations in the Ms26 gene on the A, B, and D genomes is male-sterile. Male fertility may be restored by sufficient levels of expression of Ms26 using native Ms26 or a transgene, which may be native to wheat or to another species, or a combination of native and transgenic alleles. CRISPR/Cas9 technology may be used to generate mutations in Ms26 in wheat or rice.

A highly efficient ethanol-fermentative yeast having high efficiency in ethanol production is provided without introducing a foreign gene. The highly efficient ethanol-fermentative yeast features a fermentative yeast effectively producing ethanol from pentose and hexose and being deposited to NITE Patent Microorganisms Depositary under the accession number NITE BP-01963.

A highly efficient ethanol-fermentative yeast having high efficiency in ethanol production is provided without introducing a foreign gene. The highly efficient ethanol-fermentative yeast features a fermentative yeast effectively producing ethanol from pentose and hexose and being deposited to NITE Patent Microorganisms Depositary under the accession number NITE BP-01963.

Synthetic signal transduction systems are provided. The synthetic signal transduction system may be a hormone degradable CRISPR-based transcription factor including a nuclease null Cas9 protein, a nuclear localization signal, a phytohormone degron, and a transcriptional regulation domain. Methods of generating non-naturally occurring plants are also provided. The methods may include expressing a synthetic signal transduction system in a plant. Non-naturally occurring plants formed by the methods are also provided.

Synthetic signal transduction systems are provided. The synthetic signal transduction system may be a hormone degradable CRISPR-based transcription factor including a nuclease null Cas9 protein, a nuclear localization signal, a phytohormone degron, and a transcriptional regulation domain. Methods of generating non-naturally occurring plants are also provided. The methods may include expressing a synthetic signal transduction system in a plant. Non-naturally occurring plants formed by the methods are also provided.

The present invention relates to host cells comprising a nucleic acid encoding Adeno-associated virus (AAV) Rep proteins Rep78 and Rep68, wherein the internal AAV promoter p19 has been inactivated by one or more mutations that maintain the functionality of said Rep78 and Rep68 proteins. The present invention further relates to respective nucleic acids and vectors comprising the same, as well as respective methods for the production of AAV.

The present invention relates to host cells comprising a nucleic acid encoding Adeno-associated virus (AAV) Rep proteins Rep78 and Rep68, wherein the internal AAV promoter p19 has been inactivated by one or more mutations that maintain the functionality of said Rep78 and Rep68 proteins. The present invention further relates to respective nucleic acids and vectors comprising the same, as well as respective methods for the production of AAV.

The present invention relates to a method for manufacturing microalgae micro powder containing astaxanthin and fatty acids with enhanced penetration performance and food availability, and more particularly, to a method for manufacturing microalgae micro powder containing astaxanthin and fatty acids with enhanced penetration performance and food availability, in which four kinds of functional microalgae are selected and mass-cultured so as to be processed into a dietary shape for easy penetration performance.

The present invention relates to a mutant onion (Allium cepa) plant, which is resistant to a pathogen of viral, bacterial, fungal or oomycete origin. The mutant onion plant has a reduced level, reduced activity or complete absence of AcDMR6 protein as compared to a wild type onion plant.