The present invention provides a composition having functionality to enhance immunity. Differing from all commercial vitamin healthcare foods would cause some adverse effects due to excessive vitamin intake, the present invention proposes a Solanum nigrum-fermented product to be a novel composition having functionality to enhance immunity. Moreover, animal experimental results have proved that, this novel composition would not cause any adverse effects (such as poor appetite or liver damage) even if an adult excessively administer the novel composition. In addition, comparing with the commercial healthcare foods always being made to tablets, the Solanum nigrum-fermented product (i.e., the novel composition) can be processed to various forms, such as powder, tablet, capsule, and drink.

The present invention provides a composition having functionality to enhance immunity. Differing from all commercial vitamin healthcare foods would cause some adverse effects due to excessive vitamin intake, the present invention proposes a Solanum nigrum-fermented product to be a novel composition having functionality to enhance immunity. Moreover, animal experimental results have proved that, this novel composition would not cause any adverse effects (such as poor appetite or liver damage) even if an adult excessively administer the novel composition. In addition, comparing with the commercial healthcare foods always being made to tablets, the Solanum nigrum-fermented product (i.e., the novel composition) can be processed to various forms, such as powder, tablet, capsule, and drink.

The invention relates to the fields of bacterial metabolism and the utilization or consumption of short-chain carboxylic acids to reduced products. Specifically, it relates to syngas fermentations using monocultures of syngas-utilizing homoacetogenic bacteria for the production of alcohols using native alcohol dehydrogenase.

The present disclosure provides a method for preparing an anti-wrinkle functional cosmetic substance comprising cutting herbal materials comprising angelica gigas root, rehmannia glutinosa root, a paeonia albiflora root, mentha arvensis, angelica dahurica root, scrophularia buergeriana, rheum undulatum root/stalk/stem, sanguisorba officinalis root, and cinnamomum cassia bark into pieces, putting a mixture of the herbal material pieces, talc, a pearl powder, deep ocean water into an extractor, sterilizing the mixture, then fermenting the mixture by mixed lactobacillales strain, and then hot-water extracting the mixture into a solid, freeze-drying the extracted solid into a freeze-dried powder, and dissolving and high-speed mixing the freeze-dried powder, adenosine, and borax in a beeswax, a perilla oil, an olea europaea (olive) fruit oil, and a helianthus annuus (sunflower) seed oil heated and chamaecyparis obtusa water heated.

The present disclosure provides a method for preparing an anti-wrinkle functional cosmetic substance comprising cutting herbal materials comprising angelica gigas root, rehmannia glutinosa root, a paeonia albiflora root, mentha arvensis, angelica dahurica root, scrophularia buergeriana, rheum undulatum root/stalk/stem, sanguisorba officinalis root, and cinnamomum cassia bark into pieces, putting a mixture of the herbal material pieces, talc, a pearl powder, deep ocean water into an extractor, sterilizing the mixture, then fermenting the mixture by mixed lactobacillales strain, and then hot-water extracting the mixture into a solid, freeze-drying the extracted solid into a freeze-dried powder, and dissolving and high-speed mixing the freeze-dried powder, adenosine, and borax in a beeswax, a perilla oil, an olea europaea (olive) fruit oil, and a helianthus annuus (sunflower) seed oil heated and chamaecyparis obtusa water heated.

The invention relates to the use of 1-(4,6-dipentyl-5,6-dihydro-2H-1,2,3-oxadiazin-2-yl)-3-hydroxypropan-1-one in treating and/or preventing infections caused by a bacterium, fungus or virus or in treating and/or preventing cancer. Additionally, the invention relates to a process for obtaining the compound of formula (I) of the invention, said process comprising the steps of cultivating a strain of Dolichospermum sp in an aqueous nutrient medium with assimilable carbon and nitrogen sources and salts, under controlled aerobic conditions, and then recovering the compound of general formula (I) from the culture broth.

The invention relates to the use of 1-(4,6-dipentyl-5,6-dihydro-2H-1,2,3-oxadiazin-2-yl)-3-hydroxypropan-1-one in treating and/or preventing infections caused by a bacterium, fungus or virus or in treating and/or preventing cancer. Additionally, the invention relates to a process for obtaining the compound of formula (I) of the invention, said process comprising the steps of cultivating a strain of Dolichospermum sp in an aqueous nutrient medium with assimilable carbon and nitrogen sources and salts, under controlled aerobic conditions, and then recovering the compound of general formula (I) from the culture broth.

Methods and systems for producing a biofuel using genetically modified sulfur-oxidizing and iron-reducing bacteria (SOIRB) are disclosed. In some embodiments, the methods include the following: providing a SOIRB that have been genetically modified to include a particular metabolic pathway to enable them to generate a biofuel; feeding a first source of ferric iron to the SOIRB; feeding sulfur, water, and carbon dioxide to the SOIRB; producing at least the first particular biofuel, a first source of ferrous iron, sulfate, excess ferric iron, and an SOIRB biomass; electrochemically reducing the excess ferric iron to a second source of ferrous iron; providing an iron-oxidizing bacteria that have been genetically modified to include a particular metabolic pathway to enable them to generate a second biofuel; producing at least the second biofuel, a second source of ferric iron, and an IOB biomass; and feeding the second source of ferric iron to the SOIRB.

Methods and systems for producing a biofuel using genetically modified sulfur-oxidizing and iron-reducing bacteria (SOIRB) are disclosed. In some embodiments, the methods include the following: providing a SOIRB that have been genetically modified to include a particular metabolic pathway to enable them to generate a biofuel; feeding a first source of ferric iron to the SOIRB; feeding sulfur, water, and carbon dioxide to the SOIRB; producing at least the first particular biofuel, a first source of ferrous iron, sulfate, excess ferric iron, and an SOIRB biomass; electrochemically reducing the excess ferric iron to a second source of ferrous iron; providing an iron-oxidizing bacteria that have been genetically modified to include a particular metabolic pathway to enable them to generate a second biofuel; producing at least the second biofuel, a second source of ferric iron, and an IOB biomass; and feeding the second source of ferric iron to the SOIRB.

Methods and strategies for introducing genetic safeguards into microorganisms, genetically modified organisms (GMO) including the safeguards, and methods of use thereof are provided. The genetic safeguards generally impart a low escape frequency, are robust, and are modular. Safeguards with low escape frequency prevent the rise of mutants escaping defined media and limit growth in the wild. Robust safeguards retain wild-type levels of fitness while also maintaining containment in diverse growth conditions.