A01N37/06

METHODS OF MAKING ANTIMICROBIAL COMPOSITIONS AND/OR VIRUCIDAL DISINFECTANT COMPOSITIONS FROM VEGETABLE OIL, AND RELATED ANTIMICROBIAL COMPOSITIONS AND/OR VIRUCIDAL DISINFECTANT COMPOSITIONS AND USES

The present disclosure relates to methods and systems for making one or more antimicrobial compositions and/or one or more virucidal disinfectant compositions. Said methods and systems include exposing a vegetable oil composition to ozone gas to cause ozonolysis of on one or more unsaturated fatty acids present in the vegetable oil composition, thereby forming an ozonated vegetable oil composition and exposing the ozonated vegetable oil composition to a temperature greater than 60° C. while in contact with water to decompose one or more ozonide compounds and form a heat-treated, ozonated vegetable oil composition. The present disclosure also relates to one or more uses of said one or more antimicrobial compositions and/or one or more virucidal disinfectant compositions.

METHODS OF MAKING ANTIMICROBIAL COMPOSITIONS AND/OR VIRUCIDAL DISINFECTANT COMPOSITIONS FROM VEGETABLE OIL, AND RELATED ANTIMICROBIAL COMPOSITIONS AND/OR VIRUCIDAL DISINFECTANT COMPOSITIONS AND USES

The present disclosure relates to methods and systems for making one or more antimicrobial compositions and/or one or more virucidal disinfectant compositions. Said methods and systems include exposing a vegetable oil composition to ozone gas to cause ozonolysis of on one or more unsaturated fatty acids present in the vegetable oil composition, thereby forming an ozonated vegetable oil composition and exposing the ozonated vegetable oil composition to a temperature greater than 60° C. while in contact with water to decompose one or more ozonide compounds and form a heat-treated, ozonated vegetable oil composition. The present disclosure also relates to one or more uses of said one or more antimicrobial compositions and/or one or more virucidal disinfectant compositions.

ALKYL POLYGLYCERYLAMINE BASED SURFACTANTS FOR AGRICULTURAL USE

This disclosure provides an agricultural composition comprising at least one agrochemical and at least one alkylamine glycidol surfactant of the structure I:

##STR00001## where R is C4-C22 linear or branched, saturated or non-saturated hydrocarbon group with or without pendant hydroxyl groups; x is about 0 to about 30, preferably about 1 to about 20, more preferably about 1 to about 10, more preferably about 1 to about 5; y is about 0 to about 30, preferably about 1 to about 20, more preferably about 1 to about 10, more preferably about 1 to about 5; x+y≥about 2 and up to about 30, and Gly is a glyceryl residue.

ALKYL POLYGLYCERYLAMINE BASED SURFACTANTS FOR AGRICULTURAL USE

This disclosure provides an agricultural composition comprising at least one agrochemical and at least one alkylamine glycidol surfactant of the structure I:

##STR00001## where R is C4-C22 linear or branched, saturated or non-saturated hydrocarbon group with or without pendant hydroxyl groups; x is about 0 to about 30, preferably about 1 to about 20, more preferably about 1 to about 10, more preferably about 1 to about 5; y is about 0 to about 30, preferably about 1 to about 20, more preferably about 1 to about 10, more preferably about 1 to about 5; x+y≥about 2 and up to about 30, and Gly is a glyceryl residue.

Zinc or Copper (II) Salt and Use Thereof as a Biocide

Zinc and copper (II) salts of the general formula CH.sub.2═C(R.sup.1)COO-M-OCOR.sup.2 are disclosed, wherein M-Zn or Cu, R.sup.1—H or CH.sub.3, R.sup.2—C.sub.2-C.sub.25 alkyl, or R.sup.2—CO—O— group is crotonate, or sorbate, or linoleate, excluding the compounds: CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—C.sub.2H.sub.5, CH.sub.2═CH—COO—Zn—O—CO—C.sub.2H.sub.5, CH.sub.2═CH—COO—Cu—O—CO—C.sub.2H.sub.5, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.4—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.4—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═CH—COO—Cu—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.14—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.16—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO-iso-C.sub.17H.sub.35, CH.sub.2═CH—COO—Zn—O—CO-iso-C.sub.17H.sub.35, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.17—CH.sub.3. Salts of the general formula wherein R.sup.2—C.sub.2-C.sub.25 alkyl, or R.sup.2—CO—O— group is crotonate, or sorbate, or linoleate, are applicable as biocides.

Zinc or Copper (II) Salt and Use Thereof as a Biocide

Zinc and copper (II) salts of the general formula CH.sub.2═C(R.sup.1)COO-M-OCOR.sup.2 are disclosed, wherein M-Zn or Cu, R.sup.1—H or CH.sub.3, R.sup.2—C.sub.2-C.sub.25 alkyl, or R.sup.2—CO—O— group is crotonate, or sorbate, or linoleate, excluding the compounds: CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—C.sub.2H.sub.5, CH.sub.2═CH—COO—Zn—O—CO—C.sub.2H.sub.5, CH.sub.2═CH—COO—Cu—O—CO—C.sub.2H.sub.5, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.4—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.4—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═CH—COO—Cu—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.14—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.16—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO-iso-C.sub.17H.sub.35, CH.sub.2═CH—COO—Zn—O—CO-iso-C.sub.17H.sub.35, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.17—CH.sub.3. Salts of the general formula wherein R.sup.2—C.sub.2-C.sub.25 alkyl, or R.sup.2—CO—O— group is crotonate, or sorbate, or linoleate, are applicable as biocides.

Zinc or Copper (II) Salt and Use Thereof as a Biocide

Zinc and copper (II) salts of the general formula CH.sub.2═C(R.sup.1)COO-M-OCOR.sup.2 are disclosed, wherein M-Zn or Cu, R.sup.1—H or CH.sub.3, R.sup.2—C.sub.2-C.sub.25 alkyl, or R.sup.2—CO—O— group is crotonate, or sorbate, or linoleate, excluding the compounds: CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—C.sub.2H.sub.5, CH.sub.2═CH—COO—Zn—O—CO—C.sub.2H.sub.5, CH.sub.2═CH—COO—Cu—O—CO—C.sub.2H.sub.5, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.4—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.4—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═CH—COO—Cu—O—CO—(CH.sub.2).sub.6—CH.sub.3, CH.sub.2═CH—COO—Zn—O—CO—(CH.sub.2).sub.14—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.16—CH.sub.3, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO-iso-C.sub.17H.sub.35, CH.sub.2═CH—COO—Zn—O—CO-iso-C.sub.17H.sub.35, CH.sub.2═C(CH.sub.3)—COO—Zn—O—CO—(CH.sub.2).sub.17—CH.sub.3. Salts of the general formula wherein R.sup.2—C.sub.2-C.sub.25 alkyl, or R.sup.2—CO—O— group is crotonate, or sorbate, or linoleate, are applicable as biocides.

Method of preparing hydroxytyrosol cinnamic acid ester with antioxidant and antibacterial activities

A method of preparing a compound of formula (I): ##STR00001##
is disclosed. The compound of formula (I) can be used as an antioxidant agent. The compound can also be used as an antibacterial agent to inhibit Staphylococcus aureus MRSA 18-222 and Pseudomonas aeruginosa MDR-PA 18-1774.

Method of preparing hydroxytyrosol cinnamic acid ester with antioxidant and antibacterial activities

A method of preparing a compound of formula (I): ##STR00001##
is disclosed. The compound of formula (I) can be used as an antioxidant agent. The compound can also be used as an antibacterial agent to inhibit Staphylococcus aureus MRSA 18-222 and Pseudomonas aeruginosa MDR-PA 18-1774.

Induction of a physiological dispersion response in bacterial cells in a biofilm

One aspect of the present invention is directed to a composition. The composition includes a dispersion inducer comprising:
H.sub.3C—(CH.sub.2).sub.n—CH.sub.mcustom characterCH.sub.mR,
where custom character is a single or double carbon-carbon bond, m is 1 or 2, n is 2 to 15, and R is a carboxylic acid, a salt, an ester, or an amide, where the ester or amide is an isostere or biostere of the carboxylic acid. The composition additionally contains an additive component selected from one or more of the group consisting of biocides, surfactants, antibiotics, antiseptics, detergents, chelating agents, virulence factor inhibitors, gels, polymers, pastes, edible products, and chewable products. The composition is formulated so that when it is contacted with a biofilm produced by a microorganism, where the biofilm comprises a matrix and microorganism on a surface, the dispersion inducer selectively acts on the microorganism and has a suitable biological response without a required direct effect on the matrix to disperse the biofilm. The present invention is also directed to methods of using this compound.