Patent classifications
A01N37/12
In situ generation of peroxycarboxylic acids at alkaline pH, and methods of use thereof
The present disclosure is related to percarboxylic acid compositions formed in situ in non-equilibrium reactions. The peroxycarboxylic acid compositions are formed using ester based starting materials. Methods for using the percarboxylic acid compositions are also disclosed.
In situ generation of peroxycarboxylic acids at alkaline pH, and methods of use thereof
The present disclosure is related to percarboxylic acid compositions formed in situ in non-equilibrium reactions. The peroxycarboxylic acid compositions are formed using ester based starting materials. Methods for using the percarboxylic acid compositions are also disclosed.
Topical acyclovir formulations and uses thereof
Provided herein are gel formulations of acyclovir with a low concentration of acyclovir, which can be used, for example, for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adults and adolescents 12 years of age and older. The gel formulation can be an aqueous gel formulation, an emulsified gel formulation, or a non-aqueous gel formulation.
Biofilm penetrating compositions and methods
Compositions are provided that have at least two of three active ingredients. The active ingredients maybe a salt having a cation N.sup.α C8-C6 alkanoyl-L di-basic amino acid —C1-C4 alkyl ester, a glycerol monoester of a fatty acid and a sugar ester of a fatty acid. The compositions are useful in methods of killing or inhibiting planktonic bacteria or fungi and bacteria or fungi embedded in a biofilm and prevention of biofilm formation on surfaces. The composition may further comprise a hydrogel and a benefit agent such as an antibiotic that can be solubilized by the hydrogel and supplied to the biofilm matrix by the active ingredients of the composition. Devices such as chronic wound coverings coated with the composition are also provided. Methods of preserving products with the composition are also provided.
Biofilm penetrating compositions and methods
Compositions are provided that have at least two of three active ingredients. The active ingredients maybe a salt having a cation N.sup.α C8-C6 alkanoyl-L di-basic amino acid —C1-C4 alkyl ester, a glycerol monoester of a fatty acid and a sugar ester of a fatty acid. The compositions are useful in methods of killing or inhibiting planktonic bacteria or fungi and bacteria or fungi embedded in a biofilm and prevention of biofilm formation on surfaces. The composition may further comprise a hydrogel and a benefit agent such as an antibiotic that can be solubilized by the hydrogel and supplied to the biofilm matrix by the active ingredients of the composition. Devices such as chronic wound coverings coated with the composition are also provided. Methods of preserving products with the composition are also provided.
ANTIMICROBIAL MIXTURE CONTAINING 4-(3-ETHOXY-4-HYDROXYPHENYL)BUTAN-2-ONE AND AN ALCOHOL COMPOUND, AND COSMETIC COMPOSITION CONTAINING SAME
The invention relates to an antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound chosen from hydroxyacetophenone, 5-chloro-2-(2,4-dichlorophenoxy)phenol, sorbitan caprylate, the combination of 80% to 90% by weight, relative to the total weight of said combination, of xylityl sesquicaprylate and from 10% to 20% by weight of anhydroxylitol, 4-chloro-3,5-dimethylphenol, and glyceryl caprylate, and also to a cosmetic, pharmaceutical or nutritional composition containing such a mixture.
Application to caring for, making up and cleansing keratin materials; to preserving foods and to water treatment.
ANTIMICROBIAL MIXTURE CONTAINING 4-(3-ETHOXY-4-HYDROXYPHENYL)BUTAN-2-ONE AND AN ALCOHOL COMPOUND, AND COSMETIC COMPOSITION CONTAINING SAME
The invention relates to an antimicrobial mixture containing 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one and an alcohol compound chosen from hydroxyacetophenone, 5-chloro-2-(2,4-dichlorophenoxy)phenol, sorbitan caprylate, the combination of 80% to 90% by weight, relative to the total weight of said combination, of xylityl sesquicaprylate and from 10% to 20% by weight of anhydroxylitol, 4-chloro-3,5-dimethylphenol, and glyceryl caprylate, and also to a cosmetic, pharmaceutical or nutritional composition containing such a mixture.
Application to caring for, making up and cleansing keratin materials; to preserving foods and to water treatment.
Pharmaceutical formulation for the treatment of inflammatory changes to the rectum
Disclosed is a storage-stable pharmaceutical formulation for rectal administration, containing budesonide or a pharmaceutically compatible salt or derivative thereof, and at least 80 wt % of a solid fat or a mixture of different solid fats, based on the total weight of the formulation, as well as at least one anti-oxidation agent that is compatible therewith.
Synergistic Herbicidal Combinations
A herbicide combination comprising an effective amount of components (A) and (B), where (A) denotes one or more fatty acid derivatives of the formula (I),
##STR00001##
wherein R.sup.1 is an alkyl group containing 5 to 17 carbon atoms, which is linear or branched R.sup.2, R.sup.3 are, independently, hydrogen, methyl, ethyl or hydroxymethyl with the proviso that one of R.sup.2 and R.sup.3 is hydrogen and the other is different from hydrogen m, n are numbers from 0 to 17, with the proviso that m+n≥1 and m+n+p<18 where the different monomers can be arranged in statistical order, alternatingly or as a block copolymer, R.sup.4 is hydrogen or an alkyl group containing 1 to 10 carbon atoms, which is linear or branched, and (B) denotes one or more sulfonyl urea herbicides,
is particularly suitable for controlling unwanted vegetation.
Synergistic Herbicidal Combinations
A herbicide combination comprising an effective amount of components (A) and (B), where (A) denotes one or more fatty acid derivatives of the formula (I),
##STR00001##
wherein R.sup.1 is an alkyl group containing 5 to 17 carbon atoms, which is linear or branched R.sup.2, R.sup.3 are, independently, hydrogen, methyl, ethyl or hydroxymethyl with the proviso that one of R.sup.2 and R.sup.3 is hydrogen and the other is different from hydrogen m, n are numbers from 0 to 17, with the proviso that m+n≥1 and m+n+p<18 where the different monomers can be arranged in statistical order, alternatingly or as a block copolymer, R.sup.4 is hydrogen or an alkyl group containing 1 to 10 carbon atoms, which is linear or branched, and (B) denotes one or more sulfonyl urea herbicides,
is particularly suitable for controlling unwanted vegetation.