Provided herein are compositions and their methods of use to adhere (e.g., in wet and dry environments) a variety of materials together.

The invention relates to implant materials that are based on hydraulic cements in the form of one or more pastes, suspensions or dispersions that contain mineral and/or organic and/or organomineral solids and that react, when combined or when reacted with an aqueous liquid, to a solid in a cement-type initiation reaction. The invention also relates to the use of these materials as technical, medical-technical and/or pharmaceutical products, especially as bone cements, bone replacement materials, bone glues, dental filling materials and implantable active ingredient carriers. The implant materials according to the invention in the form of one or more pastes, suspensions or dispersions that contain mineral and/or organic and/or organomineral solids are formulated in an excipient liquid in such a manner that the pastes, suspensions or dispersions are stable in storage at normal conditions over a prolonged period of time and that they react, when combined with an aqueous liquid or when added to an aqueous liquid, in a cement-type initiation reaction and set to a solid. The excipient liquid of the mineral paste, suspension or dispersion is substantially water-free, and water immiscible or insoluble or hardly soluble in water in the chemical sense.

The present disclosure relates to a dental ceramic article comprising ceramic components, the ceramic components having ZrO2 and Al2O3 and at least one component comprising Mn, Er or mixtures thereof, Al2O3 being present in an amount below about 0.15 wt.-% with respect to the weight of the ceramic article. The present disclosure relates also to kit of parts comprising a ceramic article and a coloring solution and processes for producing a dental ceramic article.

The invention relates to a solution for coloring and imparting fluorescence to a zirconia dental article, the solution comprising: •a solvent, •a coloring agent comprising ions selected from Tb, Er, Pr, Mn and combinations thereof, •a fluorescing agent comprising ions of Bi, the solution not comprising Fe ions in an amount above about 0.05 wt.-% with respect to the weight of the whole solution.

A process is provided for producing a structure into which blood or other bio-fluids can flow by capillary action, e.g. for a whole blood microsampling probe. The process comprises mixing particles of novolak resin and particles of hydrocarbon polymer, producing an uncarbonized structure from the mixture by pressurised moulding and carbonizing the moulded structure, the hydrocarbon resin being a polymer such as polystyrene that on pyrolysis has a zero carbon yield, and the particles of the hydrocarbon polymer leaving voids in the carbonized structure of sufficient size for flow of whole blood into and through the structure. The particles may be of partly cured and milled novolak resin, the novolak particles when in the moulded structure not exhibiting bulk flow during carbonization but sintering at inter-particle contact points during carbonization to provide a consolidated structure. In this variant, ethylene glycol may be used as a sintering aid. Alternatively, the particles may be of fully cured and milled novolak resin, and are mixed with the hydrocarbon polymer , the lubricant and with a binder such as lignin for providing a consolidated structure.

Various methods for laser welding biocompatible material for use in implantable medical devices are disclosed. A method for laser processing includes applying a laser beam to a biocompatible material comprising at least 85% by weight zirconium oxide (ZrO.sub.2) or “zirconia” in an oxygen-free environment and depleting the material of oxygen. The depletion of oxygen converts the zirconium oxide to elemental zirconium at an interface where the material is applied to the elemental zirconium. In one embodiment, the present invention provides for an implantable medical device or component thereof made of a biocompatible material comprising zirconium oxide. The device includes a substrate that has an intrinsic conductive pathway comprising elemental zirconium that extends from a first surface to a second surface of the substrate.

The present specification provides a dental glass ionomer cement (GIC) composition comprising a zwitterionic material and a glass ionomer cement, and a method of preparing the same.

One aspect relates to a process for producing a sintered workpiece, which includes sintering of a ceramic material at a temperature of at least 1000° C. and in an atmosphere, in the case of which the partial pressure of atmospheric air is reduced to less than 10.sup.−6-times, based on the ambient air at the same temperature under equilibrium conditions.

The present disclosure discloses a ceramic material having a positive slow release effect and a method for manufacturing the same. The ceramic material comprises a hierarchically meso-macroporous structure which composition at least includes silicon and oxygen, wherein the hierarchically meso-macroporous structure includes a plurality of macropores and a wall having a plurality of arranged mesopores, and the plurality of macropores are separated by the wall; and nano-scale metal particles confined in at least one of the plurality of arranged mesopores. The nano-scale metal particles have a positive slow release effect from the at least one of the plurality of arranged mesopores. The ceramic material has a property of inhibiting growth of microorganisms or killing the microorganisms in an environment or a system containing a hydrophilic medium.

An object of the present disclosure is to provide a dental composition that can exhibit sufficient curability even in a state where moisture is excessive as in the oral environment. The dental composition of the present disclosure contains component (a): monomer containing (meth)acrylamide group represented by formula (1): ##STR00001##
(In formula, R represents a hydrogen atom or a methyl group and Rs may be the same or different from each other. R2 is an alkyl group having 2 to 6 carbon atoms and R2s may be the same or different from each other.)