A process of converting a carbon-carbon double bond on a substrate into a cyclopropane ring, which method comprises the step of treating the substrate with a N-alkyl-N-nitroso compound, a transition metal catalyst and an aqueous base, wherein the N-alkyl-N-nitroso compound is formed by reacting an alkyl amine with an alkali metal nitrite in the presence of a mono-basic or di-basic acid, or a mixture thereof, and wherein the N-alkyl-N-nitroso compound is not distilled before it is mixed with the substrate, catalyst and base.

The present invention relates to oxocarbon-, pseudooxocarbon- and radialene compounds as well as to their use as doping agent for doping an organic semiconductive matrix material, as blocker material, as charge injection layer, as electrode material as well as organic semiconductor, as well as electronic components and organic semiconductive materials using them.

The present invention relates to oxocarbon-, pseudooxocarbon- and radialene compounds as well as to their use as doping agent for doping an organic semiconductive matrix material, as blocker material, as charge injection layer, as electrode material as well as organic semiconductor, as well as electronic components and organic semiconductive materials using them.

The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

The present disclosure relates generally to compounds (I) which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

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The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

The present disclosure relates generally to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.

Provided are a method of preparing, and use of 1-(2,2-dimethylpropyl)-cyclopropene as an ethylene antagonist that can be formulated as an aqueous emulsion and applicable to plants through immersion or spraying. It was confirmed that the compound can be reliably synthesized and stored by the preparation method disclosed herein, and it was also confirmed that the compound can effectively inhibit ethylene action when formulated as an aqueous emulsion and treated to a plant by immersion or spray treatment; hence, the compound may be used as an ethylene antagonist on plants, as a pre-harvest or post-harvest plant growth regulator, or as a freshness keeping agent.

Provided are a method of preparing, and use of 1-(2,2-dimethylpropyl)-cyclopropene as an ethylene antagonist that can be formulated as an aqueous emulsion and applicable to plants through immersion or spraying. It was confirmed that the compound can be reliably synthesized and stored by the preparation method disclosed herein, and it was also confirmed that the compound can effectively inhibit ethylene action when formulated as an aqueous emulsion and treated to a plant by immersion or spray treatment; hence, the compound may be used as an ethylene antagonist on plants, as a pre-harvest or post-harvest plant growth regulator, or as a freshness keeping agent.