The present disclosure relates in its first aspect to a process of converting a stream comprising methane into chemicals, said process being remarkable in that it comprises the steps of providing a first stream (1, 5, 11) comprising methane, providing a second stream (79) which is a bromine-rich stream, putting into contact said first stream (15) with said second stream (79) to obtain a third stream (21) comprising at least unreacted methane, methyl bromide, dibromomethane, and hydrogen bromide and removing said dibromomethane from said third stream (21), to produce a dibromomethane stream (103) and a fourth stream (27) comprising unreacted methane, methyl bromide and hydrogen bromide; wherein the fourth stream (27) is converted into chemicals. In its second aspect, the present disclosure concerns an installation for carrying out the process of the first aspect.

A method for preparing amantadine includes chlorinating adamantane with chlorine gas in a solvent in the presence of a Lewis acid catalyst to obtain a reaction liquid, and then removing the solvent and residues containing the catalyst in the reaction liquid, to obtain a chlorinated product. The chlorinated product is mixed with urea to a mixture, and the mixture is subjected to an amination reaction, to obtain amantadine. The results of examples show that the purity of the prepared amantadine could reach 99.5% or more.

A method for preparing amantadine includes chlorinating adamantane with chlorine gas in a solvent in the presence of a Lewis acid catalyst to obtain a reaction liquid, and then removing the solvent and residues containing the catalyst in the reaction liquid, to obtain a chlorinated product. The chlorinated product is mixed with urea to a mixture, and the mixture is subjected to an amination reaction, to obtain amantadine. The results of examples show that the purity of the prepared amantadine could reach 99.5% or more.

The present invention relates to a process for modifying the fluorine distribution in a hydrocarbon compound, comprising a step of making contact between said hydrocarbon compound and a catalytic composition comprising a chromium-based catalyst, said process being performed in a reactor made of a material comprising a base layer made of a material M1 and an inner layer made of a material M2, said base layer and said inner layer being laid against each other by bonding.

The present invention relates to a process for modifying the fluorine distribution in a hydrocarbon compound, comprising a step of making contact between said hydrocarbon compound and a catalytic composition comprising a chromium-based catalyst, said process being performed in a reactor made of a material comprising a base layer made of a material M1 and an inner layer made of a material M2, said base layer and said inner layer being laid against each other by bonding.

The present invention relates to a synthesis method and synthesis reactor of high-selectivity 2-methylallyl chloride by taking isobutylene and chlorine gas as raw materials and performing a gas-phase chlorination reaction in a microchannel reactor with a cooling surface. The isobutylene and the chlorine gas are reacted in a T-shaped microchannel reactor, and the mixing speed is extremely fast. Meanwhile, the huge heat exchange area per unit volume can ensure that the reaction proceeds stably at a substantially constant temperature and has good controllability. Therefore, side reactions caused by excessive local temperature can be effectively suppressed, the reaction selectivity is high, and no coking phenomenon occurs.

The present invention relates to a synthesis method and synthesis reactor of high-selectivity 2-methylallyl chloride by taking isobutylene and chlorine gas as raw materials and performing a gas-phase chlorination reaction in a microchannel reactor with a cooling surface. The isobutylene and the chlorine gas are reacted in a T-shaped microchannel reactor, and the mixing speed is extremely fast. Meanwhile, the huge heat exchange area per unit volume can ensure that the reaction proceeds stably at a substantially constant temperature and has good controllability. Therefore, side reactions caused by excessive local temperature can be effectively suppressed, the reaction selectivity is high, and no coking phenomenon occurs.

The present invention relates to a synthesis method and synthesis reactor of high-selectivity 2-methylallyl chloride by taking isobutylene and chlorine gas as raw materials and performing a gas-phase chlorination reaction in a microchannel reactor with a cooling surface. The isobutylene and the chlorine gas are reacted in a T-shaped microchannel reactor, and the mixing speed is extremely fast. Meanwhile, the huge heat exchange area per unit volume can ensure that the reaction proceeds stably at a substantially constant temperature and has good controllability. Therefore, side reactions caused by excessive local temperature can be effectively suppressed, the reaction selectivity is high, and no coking phenomenon occurs.

A method for preparing amantadine includes chlorinating adamantane with chlorine gas in a solvent in the presence of a Lewis acid catalyst to obtain a reaction liquid, and then removing the solvent and residues containing the catalyst in the reaction liquid, to obtain a chlorinated product. The chlorinated product is mixed with urea to a mixture, and the mixture is subjected to an amination reaction, to obtain amantadine. The results of examples show that the purity of the prepared amantadine could reach 99.5% or more.

A method for preparing amantadine includes chlorinating adamantane with chlorine gas in a solvent in the presence of a Lewis acid catalyst to obtain a reaction liquid, and then removing the solvent and residues containing the catalyst in the reaction liquid, to obtain a chlorinated product. The chlorinated product is mixed with urea to a mixture, and the mixture is subjected to an amination reaction, to obtain amantadine. The results of examples show that the purity of the prepared amantadine could reach 99.5% or more.