Disclosed herein are processes for preparing certain intermediates useful in the synthesis of 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)oxy)benzonitrile or a pharmaceutically acceptable salt thereof.

Disclosed herein are processes for preparing certain intermediates useful in the synthesis of 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)oxy)benzonitrile or a pharmaceutically acceptable salt thereof.

An improved process for the recovery of high-purity ethylene-oxide water feed streams to EO purification and MEG reaction units when both are operating in EO plants that incorporate EO Stripper bypass technology, by installing a second lights stripper to exclusively degasify the diluted EO feed to the MEG reactor, thus permitting the use of additional bypassed (gasified) EO absorbate as the diluent and resulting in a substantial increase in the total amount of EO absorbate that can bypass the EO Stripper.

An improved process for the recovery of high-purity ethylene-oxide water feed streams to EO purification and MEG reaction units when both are operating in EO plants that incorporate EO Stripper bypass technology, by installing a second lights stripper to exclusively degasify the diluted EO feed to the MEG reactor, thus permitting the use of additional bypassed (gasified) EO absorbate as the diluent and resulting in a substantial increase in the total amount of EO absorbate that can bypass the EO Stripper.

The presently claimed invention relates to a process for the recovery of 3-methyl-3-buten- -ol from a stream comprising (Z)-3-methylpent-2-ene-1,5-diol, (E)-3-methylpent-2-ene-,5-diol and 3-methylenepentane-1,5-diol by treating the stream with isobutene and water.

The presently claimed invention relates to a process for the recovery of 3-methyl-3-buten- -ol from a stream comprising (Z)-3-methylpent-2-ene-1,5-diol, (E)-3-methylpent-2-ene-,5-diol and 3-methylenepentane-1,5-diol by treating the stream with isobutene and water.

The presently claimed invention relates to a process for the recovery of 3-methyl-3-buten- -ol from a stream comprising (Z)-3-methylpent-2-ene-1,5-diol, (E)-3-methylpent-2-ene-,5-diol and 3-methylenepentane-1,5-diol by treating the stream with isobutene and water.

Compositions comprising 3-hexen-1-ol are described herein, as well as odor-imparting formulations comprising same and articles-of-manufacturing comprising such compositions or odor-imparting formulations. The compositions comprise trans-3-hexen-1-ol in a range of from 67% to 82% by weight and cis-3-hexen-1-ol in a range of from 18% to 33% by weight, wherein a total concentration of trans-3-hexen-1-ol and cis-3-hexen-1-ol is at least 97% by weight. Further described herein is a process for preparing a composition comprising 3-hexen-1-ol, the process comprising: contacting 1-pentene with a formaldehyde in the presence of a Lewis acid to thereby obtain a crude mixture comprising 3-hexen-1-ol; and contacting the mixture comprising 3-hexen-1-ol with a base.

Compositions comprising 3-hexen-1-ol are described herein, as well as odor-imparting formulations comprising same and articles-of-manufacturing comprising such compositions or odor-imparting formulations. The compositions comprise trans-3-hexen-1-ol in a range of from 67% to 82% by weight and cis-3-hexen-1-ol in a range of from 18% to 33% by weight, wherein a total concentration of trans-3-hexen-1-ol and cis-3-hexen-1-ol is at least 97% by weight. Further described herein is a process for preparing a composition comprising 3-hexen-1-ol, the process comprising: contacting 1-pentene with a formaldehyde in the presence of a Lewis acid to thereby obtain a crude mixture comprising 3-hexen-1-ol; and contacting the mixture comprising 3-hexen-1-ol with a base.

The present disclosure relates to a multi-sandwich composite catalyst and a preparation method and application thereof. The present disclosure provides a preparation method of a multi-sandwich composite catalyst, comprises the following steps: sequentially depositing a first layer oxide, a first active metal, an oxide interlayer, a second active metal and a surface oxide on a template, and sequentially performing calcination and reduction, thereby obtaining a multi-sandwich composite catalyst; wherein the first active metal and the second active metal are different kinds of active metals. In the present disclosure, a multi-sandwich structure is formed by depositing the oxides and active metals alternately, so that the position and spacing distance of the active centers can be precisely controlled. The multi-sandwich composite catalyst prepared by the method provided described herein has a higher conversion than that of a catalyst without an interlayer when used for the catalytic reaction.