C07C33/14

2-(2,4,5-TRIMETHYLCYCLOHEX-2-EN-1-YL)ACETALDEHYDE AND DERIVATIVES AND THEIR USE AS AROMA CHEMICALS

The present invention relates to 2-(2,4,5-trimethylcyclohex-2-en-1-yl)acetaldehyde and derivatives thereof, to a process for preparing said compounds, to the use of 2-(2,4,5-trimethylcyclohex-2-en-1-yl)acetaldehyde or a specific derivative thereof or of mixtures of said compounds or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof as aroma chemicals; to the use of 2-(2,4,5-trimethylcyclohex-2-en-1-yl)acetaldehyde or a specific derivative thereof for modifying the scent character of a fragranced composition; to compositions containing 2-(2,4,5-trimethylcyclohex-2-en-1-yl)acetaldehyde or a specific derivative thereof or a mixture of said compounds or a stereoisomer thereof or a mixture of two or more stereoisomers thereof; and to a method of preparing a fragranced composition or for modifying the scent character of a fragranced composition, comprising incorporating 2-(2,4,5-trimethylcyclohex-2-en-1-yl)-acetaldehyde or a specific derivative thereof or a mixture of said compounds or a stereoisomer thereof or a mixture of two or more stereoisomers thereof into said composition.

SELECTIVE HYDROGENATION OF ALKYNES TO ALKENES IN THE PRESENCE OF A PHOSPHORUS COMPOUND AND AN ORGANIC SULPHUR COMPOUND
20220242807 · 2022-08-04 ·

The present invention relates to a process of hydrogenating an alkyne selectively to an alkene by hydrogen using a hydrogenation catalyst which is palladium supported on a carrier in the presence of an additive mixture of an organic phosphorus compound (AP) and an organic sulphur compound (AS).

Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds
20220089508 · 2022-03-24 ·

A method of reducing an aromatic ring or a cyclic, allylic ether in a compound includes preparing a reaction mixture including a compound including an aromatic moiety or a cyclic, allylic ether moiety, an alkali metal, and either ethylenediamine, diethylenetriamine, triethylenetetramine, or a combination thereof, in an ether solvent; and reacting the reaction mixture at from −20° C. to 30° C. for a time sufficient to reduce a double bond in the aromatic moiety to a single bond or to reduce the cyclic, allylic ether moiety.

Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds
20220089508 · 2022-03-24 ·

A method of reducing an aromatic ring or a cyclic, allylic ether in a compound includes preparing a reaction mixture including a compound including an aromatic moiety or a cyclic, allylic ether moiety, an alkali metal, and either ethylenediamine, diethylenetriamine, triethylenetetramine, or a combination thereof, in an ether solvent; and reacting the reaction mixture at from −20° C. to 30° C. for a time sufficient to reduce a double bond in the aromatic moiety to a single bond or to reduce the cyclic, allylic ether moiety.

CARBON-BASED, PRECIOUS METAL-TRANSITION METAL COMPOSITE CATALYST AND PREPARATION METHOD THEREFOR
20220062868 · 2022-03-03 ·

The present invention relates to a carbon-based precious metal-transition metal composite catalyst and a preparation method therefor, and more particularly, to a catalyst synthesis method in which, when preparing a high-content precious metal-transition metal composite catalyst, a catalyst having uniform particles and composition can be prepared, and cyclohexane dimethanol (CHDM) is efficiently produced by the hydrogenation reaction of cyclohexane dicarboxylic acid (CHDA) in an aqueous solution. Provided is a method for preparing a carbon-based precious metal-transition metal composite catalyst, wherein, in the carbon-based precious metal-transition metal composite catalyst, the precious metal is included in an amount of 10-20 parts by weight, and the transition metal is included in an amount of 10-20 parts by weight based on 100 parts by weight of the composite catalyst, and thus a total amount of the precious metal-transition metal is 20-40 parts by weight based on 100 parts by weight of the composite catalyst.

CARBON-BASED, PRECIOUS METAL-TRANSITION METAL COMPOSITE CATALYST AND PREPARATION METHOD THEREFOR
20220062868 · 2022-03-03 ·

The present invention relates to a carbon-based precious metal-transition metal composite catalyst and a preparation method therefor, and more particularly, to a catalyst synthesis method in which, when preparing a high-content precious metal-transition metal composite catalyst, a catalyst having uniform particles and composition can be prepared, and cyclohexane dimethanol (CHDM) is efficiently produced by the hydrogenation reaction of cyclohexane dicarboxylic acid (CHDA) in an aqueous solution. Provided is a method for preparing a carbon-based precious metal-transition metal composite catalyst, wherein, in the carbon-based precious metal-transition metal composite catalyst, the precious metal is included in an amount of 10-20 parts by weight, and the transition metal is included in an amount of 10-20 parts by weight based on 100 parts by weight of the composite catalyst, and thus a total amount of the precious metal-transition metal is 20-40 parts by weight based on 100 parts by weight of the composite catalyst.

PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES
20210283127 · 2021-09-16 ·

The present invention provides for a derivative of monoterpene or sesquiterpene, such as a perillyl alcohol derivative. For example, the perillyl alcohol derivative may be a perillyl alcohol carbamate. The perillyl alcohol derivative may be perillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The present invention also provides for a method of treating a disease such as cancer, comprising the step of delivering to a patient a therapeutically effective amount of a derivative of monoterpene (or sesquiterpene). The route of administration may vary, and can include, inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.

PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES
20210283127 · 2021-09-16 ·

The present invention provides for a derivative of monoterpene or sesquiterpene, such as a perillyl alcohol derivative. For example, the perillyl alcohol derivative may be a perillyl alcohol carbamate. The perillyl alcohol derivative may be perillyl alcohol conjugated with a therapeutic agent such as a chemotherapeutic agent. The present invention also provides for a method of treating a disease such as cancer, comprising the step of delivering to a patient a therapeutically effective amount of a derivative of monoterpene (or sesquiterpene). The route of administration may vary, and can include, inhalation, intranasal, oral, transdermal, intravenous, subcutaneous or intramuscular injection.

FRAGRANCE AND FLAVOR MATERIALS

The synthesis and application of compounds having unique and desired flavor and/or fragrance characteristics are provided herein. The compounds herein can be employed alone or incorporated as fragrance or flavor ingredients in fragrance or flavor compositions. The application is also directed to consumer products comprising such derivatives and/or fragrance or flavor compositions.

COLD EXTRACTION METHOD FOR CANNABINOIDS AND TERPENES FROM CANNABIS BY POLYUNSATURATED LIPID-BASED SOLVENTS
20210291073 · 2021-09-23 ·

The invention relates to methods for producing botanical extracts comprising cannabinoids and terpenes using cold extraction with highly polyunsaturated lipid solvents. These methods allow for the extraction of cannabinoids and terpenes while leaving behind impurities that are commonly found in organic solvent extraction methods.