An asphaltene dispersant composition is provided. The composition may contain an alkylphenol copolymer having the following repeating units (A) and (B): ##STR00001##
wherein, x is an integer from 1 to 200; y is an integer from 2 to 200; R.sub.1 is a straight or branched C.sub.1-C.sub.15 alkyl; and R.sub.2 is a straight or branched C.sub.2-C.sub.40 alkyl, wherein R.sub.2 is different than R.sub.1.

An asphaltene dispersant composition is provided. The composition may contain an alkylphenol copolymer having the following repeating units (A) and (B): ##STR00001##
wherein, x is an integer from 1 to 200; y is an integer from 2 to 200; R.sub.1 is a straight or branched C.sub.1-C.sub.15 alkyl; and R.sub.2 is a straight or branched C.sub.2-C.sub.40 alkyl, wherein R.sub.2 is different than R.sub.1.

An alkylphenol copolymer, such as for use in a petroleum composition, is provided. The alkylphenol copolymer has the following repeating units (A) and (B): ##STR00001##
wherein, x is an integer from 1 to 200; y is an integer from 2 to 200; R.sub.1 is a straight or branched C.sub.1-C.sub.15 alkyl; and R.sub.2 is a straight or branched C.sub.2-C.sub.40 alkyl, wherein R.sub.2 is different than R.sub.1.

An alkylphenol copolymer, such as for use in a petroleum composition, is provided. The alkylphenol copolymer has the following repeating units (A) and (B): ##STR00001##
wherein, x is an integer from 1 to 200; y is an integer from 2 to 200; R.sub.1 is a straight or branched C.sub.1-C.sub.15 alkyl; and R.sub.2 is a straight or branched C.sub.2-C.sub.40 alkyl, wherein R.sub.2 is different than R.sub.1.

The present invention provides an efficient process for the isolation of natural crystallized thymol product derived from crude natural Monarda citriodora (Jammu Monarda) oil useful for incorporation into foods and beverages in amounts due to strong antimicrobial, antibacterial, antioxidant properties as well as for use as a preservative. The recovery of crystallized thymol product obtained is more than 72% from Hexane-Jammu Monarda oil in a ratio 1:1 under specific conditions. A method for preparing natural thymol in crystal form involves providing crude Jammu Monarda oil in a Flask and gradually reducing the temperature of the flask containing Monarda oil: Hexane in a step-wise manner, thereby producing highly pure crystals (95.5%) within 48 h. The methods disclosed herein are suitable for pharmaceutical GMP.

The present invention provides an efficient process for the isolation of natural crystallized thymol product derived from crude natural Monarda citriodora (Jammu Monarda) oil useful for incorporation into foods and beverages in amounts due to strong antimicrobial, antibacterial, antioxidant properties as well as for use as a preservative. The recovery of crystallized thymol product obtained is more than 72% from Hexane-Jammu Monarda oil in a ratio 1:1 under specific conditions. A method for preparing natural thymol in crystal form involves providing crude Jammu Monarda oil in a Flask and gradually reducing the temperature of the flask containing Monarda oil: Hexane in a step-wise manner, thereby producing highly pure crystals (95.5%) within 48 h. The methods disclosed herein are suitable for pharmaceutical GMP.

A polyisobutylene-substituted hydroxyaromatic compound and derivatives thereof which are suitable for use as additives in lubricating compositions. The polyisobutylene-substituted hydroxyaromatic compound may include the reaction product of a hydroxyaromatic compound with a polyisobutylene having a number average molecular weight of 150 to 800.

A polyisobutylene-substituted hydroxyaromatic compound and derivatives thereof which are suitable for use as additives in lubricating compositions. The polyisobutylene-substituted hydroxyaromatic compound may include the reaction product of a hydroxyaromatic compound with a polyisobutylene having a number average molecular weight of 150 to 800.

A polyisobutylene-substituted hydroxyaromatic compound and derivatives thereof which are suitable for use as additives in lubricating compositions. The polyisobutylene-substituted hydroxyaromatic compound may include the reaction product of a hydroxyaromatic compound with a polyisobutylene having a number average molecular weight of 150 to 800.

Provided are compounds of formulae provided herein. The compounds may include pathway-preferential estrogens (PaPEs) derivatives with tissue-selective activities. Also provided are pharmaceutical compositions comprising the compounds, as well as methods of treating a disease or condition including administering the compounds. The disease or condition may include postmenopausal symptoms, cardiovascular disease, stroke, vascular disease, bone disease, metabolic disease, arthritis, osteoporosis, obesity, vasomotor/hot flush, cognitive decline, cancer including breast cancer.