Methods for total chemical synthesis of Resolvin E1 (RvE1) include Wittig reaction of two compounds having hydroxyl protecting group in the presence of a strong base, removal of the hydroxyl-protecting groups with a deprotecting reagent to produce a compound having an ester group, and hydrolysis of the ester group to obtain RvE1

The present invention discloses a method for preparing optically active carbonyl compound, comprising the following steps: under the catalysis of chiral amine salt and transition metal catalysts, with hydrogen and catalytic amount of dihydropyridine compound as hydrogen source, use , -unsaturated aldehydes or , -unsaturated troponoid compounds to conduct asymmetric catalytic reaction to obtain the optically active carbonyl compound. This method comes in moderate reaction condition, simple operation, and catalytic amount of dihydropyridine compounds usage, the target product is easy to be separated and purified from the reaction system, and the metal catalyst can be recycled, it is economical.

The present invention discloses a method for preparing optically active carbonyl compound, comprising the following steps: under the catalysis of chiral amine salt and transition metal catalysts, with hydrogen and catalytic amount of dihydropyridine compound as hydrogen source, use , -unsaturated aldehydes or , -unsaturated troponoid compounds to conduct asymmetric catalytic reaction to obtain the optically active carbonyl compound. This method comes in moderate reaction condition, simple operation, and catalytic amount of dihydropyridine compounds usage, the target product is easy to be separated and purified from the reaction system, and the metal catalyst can be recycled, it is economical.

Polyethylene glycol derivatives of the following formula I and uses thereof are disclosed. A method for manufacturing the polyethylene glycol derivatives is also disclosed. ##STR00001##

Polyethylene glycol derivatives of the following formula I and uses thereof are disclosed. A method for manufacturing the polyethylene glycol derivatives is also disclosed. ##STR00001##

Shown is a bimesogenic compound having high solubility in a liquid crystal compound, a liquid crystal composition, a chiral dopant, an additive including an antioxidant or an ultraviolet light absorber, and a polymerizable liquid crystal compound, each of which is used in other bimesogenic compounds or a liquid crystal display device, while maintaining desired physical properties.

A compound is represented by formula (1), a liquid crystal composition contains the compound, conjugate fibers with an encapsulated liquid crystal obtained from the liquid crystal composition, and a liquid crystal display device is obtained from the conjugate fibers with the encapsulated liquid crystal.

MG.sup.1-Z.sup.a-Sp-Z.sup.b-MG.sup.2(1)

The present invention is related to substituted butanol derivatives of the formula:

##STR00001##

wherein R is an unsubstituted or substituted C.sub.1-6 straight chain alkyl, an unsubstituted or substituted C.sub.3-6 branched chain alkyl, an unsubstituted or substituted C.sub.3-6 straight chain alkenyl, an unsubstituted or substituted C.sub.3-6 branched chain alkenyl, an unsubstituted or substituted C.sub.3-6 cycloalkyl, an unsubstituted or substituted C.sub.1-6 alkoxy, nitrile, halo, amino, an unsubstituted or substituted C.sub.1-6 alkylamino, an unsubstituted or substituted C.sub.1-6 dialkylamino, carboxy-C.sub.1-6 alkylamino, carboxy-C.sub.1-6 dialkylamino, an unsubstituted or substituted acetoxy, carboxy, an unsubstituted or substituted carboxyethyl, an unsubstituted or substituted C.sub.1-6 alkylcarbonyl, an unsubstituted or substituted C.sub.1-6 alkylcarboxy, an unsubstituted or substituted C.sub.1-6 alkylthio, an unsubstituted or substituted C.sub.1-6 alkyloxy, carboxamido, an unsubstituted or substituted C.sub.1-6 alkylcarboxamido or an unsubstituted or substituted C.sub.1-6 dialkylcarboxamido. Such compounds are useful in flavor or flavor compositions.

The present invention is related to substituted butanol derivatives of the formula:

##STR00001##

wherein R is an unsubstituted or substituted C.sub.1-6 straight chain alkyl, an unsubstituted or substituted C.sub.3-6 branched chain alkyl, an unsubstituted or substituted C.sub.3-6 straight chain alkenyl, an unsubstituted or substituted C.sub.3-6 branched chain alkenyl, an unsubstituted or substituted C.sub.3-6 cycloalkyl, an unsubstituted or substituted C.sub.1-6 alkoxy, nitrile, halo, amino, an unsubstituted or substituted C.sub.1-6 alkylamino, an unsubstituted or substituted C.sub.1-6 dialkylamino, carboxy-C.sub.1-6 alkylamino, carboxy-C.sub.1-6 dialkylamino, an unsubstituted or substituted acetoxy, carboxy, an unsubstituted or substituted carboxyethyl, an unsubstituted or substituted C.sub.1-6 alkylcarbonyl, an unsubstituted or substituted C.sub.1-6 alkylcarboxy, an unsubstituted or substituted C.sub.1-6 alkylthio, an unsubstituted or substituted C.sub.1-6 alkyloxy, carboxamido, an unsubstituted or substituted C.sub.1-6 alkylcarboxamido or an unsubstituted or substituted C.sub.1-6 dialkylcarboxamido. Such compounds are useful in flavor or flavor compositions.

The invention relates to terpene-derived acids and esters thereof as well as to processes for synthesizing them.

The invention relates to terpene-derived acids and esters thereof as well as to processes for synthesizing them.