The disclosure relates to an entecavir intermediate, a synthetic method therefor, and the synthetic method for entecavir by using the intermediate. According to the disclosure, the synthetic methods for entecavir and the intermediate thereof have the advantages of being controllable in chirality, high in yield and product purity, wide in source of raw materials, cheap and available in reagents, simple in reactions, convenient to operate, environmentally friendly, and suitable for industrial amplification production.

The disclosure relates to an entecavir intermediate, a synthetic method therefor, and the synthetic method for entecavir by using the intermediate. According to the disclosure, the synthetic methods for entecavir and the intermediate thereof have the advantages of being controllable in chirality, high in yield and product purity, wide in source of raw materials, cheap and available in reagents, simple in reactions, convenient to operate, environmentally friendly, and suitable for industrial amplification production.

A polymer-catalyst assembly includes polarized polymeric nanofibers retaining a plurality of catalytic metallic nanoparticles. A method of making the polarized polymer-catalyst assembly may include providing a fiber mat having polymeric nanofibers retaining a plurality of catalytic metallic nanoparticles, stretching the fiber mat in a uniaxial direction, simultaneous with the step of stretching, thermally heating the fiber mat, simultaneous with the steps of stretching and thermally heating, subjecting the fiber mat to an electric field, whereby the simultaneous steps of stretching, thermally heating, and subjecting thereby form a polarized fiber mat.

A polymer-catalyst assembly includes polarized polymeric nanofibers retaining a plurality of catalytic metallic nanoparticles. A method of making the polarized polymer-catalyst assembly may include providing a fiber mat having polymeric nanofibers retaining a plurality of catalytic metallic nanoparticles, stretching the fiber mat in a uniaxial direction, simultaneous with the step of stretching, thermally heating the fiber mat, simultaneous with the steps of stretching and thermally heating, subjecting the fiber mat to an electric field, whereby the simultaneous steps of stretching, thermally heating, and subjecting thereby form a polarized fiber mat.

The present invention concerns a method of oxidizing a cycloalkane to form a product mixture containing a corresponding alcohol and ketone, said method comprising contacting the cycloalkane with a hydroperoxide compound in the presence of a heterogenous catalyst comprising gold.

The present invention concerns a method of oxidizing a cycloalkane to form a product mixture containing a corresponding alcohol and ketone, said method comprising contacting the cycloalkane with a hydroperoxide compound in the presence of a heterogenous catalyst comprising gold.

Disclosed are a process for abating 3-cyclohexenone from a feed mixture comprising 3-cylclohexenone and cyclohexanone, comprising a hydrogenation step of contacting the feed mixture with hydrogen in the presence of a hydrogenation catalyst under hydrogenation conditions to obtain a hydrogenated mixture, cyclohexanone-containing products comprising 3-cyclohexenone and/or 2-cyclohexenone at low concentrations, and compositions of matter useful for making such cyclohexanone-containing products, particularly by using such processes.

Disclosed are a process for abating 3-cyclohexenone from a feed mixture comprising 3-cylclohexenone and cyclohexanone, comprising a hydrogenation step of contacting the feed mixture with hydrogen in the presence of a hydrogenation catalyst under hydrogenation conditions to obtain a hydrogenated mixture, cyclohexanone-containing products comprising 3-cyclohexenone and/or 2-cyclohexenone at low concentrations, and compositions of matter useful for making such cyclohexanone-containing products, particularly by using such processes.

Disclosed are a process for abating 3-cyclohexenone from a feed mixture comprising 3-cylclohexenone and cyclohexanone, comprising a hydrogenation step of contacting the feed mixture with hydrogen in the presence of a hydrogenation catalyst under hydrogenation conditions to obtain a hydrogenated mixture, cyclohexanone-containing products comprising 3-cyclohexenone and/or 2-cyclohexenone at low concentrations, and compositions of matter useful for making such cyclohexanone-containing products, particularly by using such processes.

The present disclosure relates to a process for acid-catalyzed decomposition of aryl -hydroperoxide with a continuous flow tubular reactor. The process is a novel process performed in a tubular reactor, taking the aryl -hydroperoxide such as cumene hydroperoxide (CHP) as a raw material and taking acids as a catalyst, performing acid-catalyzed decomposition of the aryl -hydroperoxide solution in a short reaction time ranging from tens of seconds to several minutes, thereby obtaining the phenols; wherein an inert component may be filled in the reactor, so that the effects of heat transmission and mass transfer can be enhanced. The aryl -hydroperoxide and acid are respectively introduced by a metering pump into a mixing module to be mixed, and then enter the tubular reactor to be reacted so as to produce the products such as phenols.