C07C49/657

THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF
20180134679 · 2018-05-17 · ·

The invention provides compounds that are useful for treating or preventing cancer.

THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF
20180134679 · 2018-05-17 · ·

The invention provides compounds that are useful for treating or preventing cancer.

Catalysts, ligands and use thereof

According to the present invention, there is provided a catalytic complex comprising a metal, one or more ligands and one or more counterions, wherein said one or more ligands include a non-racemic chiral ligand and wherein said one or more counterions include a triflimide counterion. Also provided are methods of making said catalytic complex and processes for producing chiral compounds which involve the use of said catalytic complex. In addition, the present invention provides compounds of the formula (2) as defined herein. The compounds of formula (2) may be useful as ligands in catalytic complexes.

Catalysts, ligands and use thereof

According to the present invention, there is provided a catalytic complex comprising a metal, one or more ligands and one or more counterions, wherein said one or more ligands include a non-racemic chiral ligand and wherein said one or more counterions include a triflimide counterion. Also provided are methods of making said catalytic complex and processes for producing chiral compounds which involve the use of said catalytic complex. In addition, the present invention provides compounds of the formula (2) as defined herein. The compounds of formula (2) may be useful as ligands in catalytic complexes.

1,3-cyclohexanedione derivatives and 1,3-cyclopentanedione derivatives as buffering molecules in non-aqueous solutions

This invention relates to 1,3-cyclohexanedione derivatives and 1,3-cyclopentanedione derivatives that have buffering function in non-aqueous solutions and to the use thereof for tuning the conditions to control chemical events in non-aqueous solutions. One aspect of the invention is a method for buffering a non-aqueous solution, including adding a buffering molecule to the non-aqueous solution, in which the non-aqueous solution contains an organic solvent, the buffering molecule is a 1,3-cyclohexanedione derivative or a 1,3-cyclopentanedione derivative, and the buffering molecule is optionally conjugated to a solid support.

1,3-cyclohexanedione derivatives and 1,3-cyclopentanedione derivatives as buffering molecules in non-aqueous solutions

This invention relates to 1,3-cyclohexanedione derivatives and 1,3-cyclopentanedione derivatives that have buffering function in non-aqueous solutions and to the use thereof for tuning the conditions to control chemical events in non-aqueous solutions. One aspect of the invention is a method for buffering a non-aqueous solution, including adding a buffering molecule to the non-aqueous solution, in which the non-aqueous solution contains an organic solvent, the buffering molecule is a 1,3-cyclohexanedione derivative or a 1,3-cyclopentanedione derivative, and the buffering molecule is optionally conjugated to a solid support.

1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I)

This invention provides for use of a compound of formula (1) for inhibiting a post-germination ethylene production response in a plant or plant part and a method of inhibiting a post-germination ethylene production response of a plant or plant part comprising delivering a compound of formula (1) to a plant or plant part.

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1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID OXIDASE INHIBITORS (ACO-I)

This invention provides for use of a compound of formula (1) for inhibiting a post-germination ethylene production response in a plant or plant part and a method of inhibiting a post-germination ethylene production response of a plant or plant part comprising delivering a compound of formula (1) to a plant or plant part.

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