The present invention relates to the synthesis of a variety of metal organic frameworks (MOFs) using low temperature and solvents which are considered to be not particularly harmful to the environment. There is also provided novel MOFs which may be made by the desired processes.

The present invention discloses pharmaceutical-grade ferric organic compounds, including ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. A manufacturing and quality control process for making a pharmaceutical-grade ferric citrate that consistently complies with the established Manufacture Release Specification is also disclosed. The pharmaceutical-grade ferric organic compounds are suitable for treating disorders characterized by elevated serum phosphate levels.

The present invention discloses pharmaceutical-grade ferric organic compounds, including ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. A manufacturing and quality control process for making a pharmaceutical-grade ferric citrate that consistently complies with the established Manufacture Release Specification is also disclosed. The pharmaceutical-grade ferric organic compounds are suitable for treating disorders characterized by elevated serum phosphate levels.

Methods and processes for preparing calcium salts of alpha-ketoglutarate are described herein.

A method for producing an indium carboxylate of the present invention comprises the steps of reacting a hydroxyl group-containing indium carboxylate represented by Formula (1): In(RCOO).sub.3-x(OH).sub.x, wherein R is a straight chain or branched chain aliphatic group having 0 to 5 carbon atoms, and x is a number more than 0 and less than 3, with a lower carboxylic acid represented by the following Formula (2): R′COOH, wherein R′ is a hydrogen atom or a straight chain or branched chain aliphatic group having 1 to 5 carbon atoms, and the hydrogen atom in the aliphatic group may be replaced with a halogen atom, so as to obtain a product; and then reacting the product with a higher carboxylic acid having 12 or more carbon atoms.

Methods for fabrication of and use of magnesium oxide sorbents for room temperature carbon dioxide adsorption are provided. In accordance with one aspect, a method for fabrication of sorbents is provided which includes using calcination to obtain MgO—Mg(OH).sub.2 nano-composites and aging the MgO—Mg(OH).sub.2 nano-composites to form nano MCHs for room temperature carbon dioxide adsorption. According to another aspect, a method for fabrication of sorbents which includes fabrication of monoclinic magnesium malate tetrahydrate (C.sub.8H.sub.10MgO.sub.10.4H.sub.2O) and use of such sorbents for room temperature carbon dioxide adsorption is provided.

A process for producing a bimetallic, terephthalate metal organic framework (MOF) having a flexible structure and comprising aluminum and iron cations, comprises contacting a water-soluble aluminum salt, a chelated iron compound and 1,4-benzenedicarboxylic acid or a salt thereof with a fluoride-free mixture of water and a polar organic solvent at a reaction temperature of less than 200° C. to produce a solid reaction product comprising the MOF.

A process for producing a bimetallic, terephthalate metal organic framework (MOF) having a flexible structure and comprising aluminum and iron cations, comprises contacting a water-soluble aluminum salt, a chelated iron compound and 1,4-benzenedicarboxylic acid or a salt thereof with a fluoride-free mixture of water and a polar organic solvent at a reaction temperature of less than 200° C. to produce a solid reaction product comprising the MOF.

The present invention discloses pharmaceutical-grade ferric organic compounds, including ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. A manufacturing and quality control process for making a pharmaceutical-grade ferric citrate that consistently complies with the established Manufacture Release Specification is also disclosed. The pharmaceutical-grade ferric organic compounds are suitable for treating disorders characterized by elevated serum phosphate levels.

The present invention provides a metal salt of malonic acid derivative compound having chemical formula (I) as an α-nucleating agent and process for preparing the same. The present invention also provides a polymer additive and thermoplastic composition comprising the metal salt of malonic acid derivative compound having chemical formula (I). ##STR00001##