Patent classifications
C07C51/60
METHOD FOR PRODUCING FLUORINATED HYDROCARBONS
Provided is a method for industrially advantageously producing a fluorinated hydrocarbon (3). The disclosed method for producing a fluorinated hydrocarbon represented by formula (3) includes bringing into contact, in a hydrocarbon-based solvent, a secondary or tertiary ether compound represented by formula (1) below with an acid fluoride represented by formula (2) in the presence of lithium salt or sodium salt (in the formulae, R.sup.1 and R.sup.2 each represent a C.sub.1-3 alkyl, and R.sup.1 and R.sup.2 may be bonded to each other to form a ring structure; R.sup.3 represents a hydrogen atom, methyl, or ethyl; and R.sup.4 and R.sup.5 each represent methyl or ethyl).
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Method for producing acid halide solution, mixed solution, and method for producing monoester compound
The present disclosure provides a method for producing an acid halide solution that is useful as a production intermediate or the like that allows industrially advantageous production of a polymerizable liquid crystal compound. The method for producing an acid halide solution of the present disclosure includes a step of reacting a halogenating agent and a dicarboxylic acid compound in a water-immiscible organic solvent in the presence of a tetraalkylammonium salt to obtain a water-immiscible organic solvent solution including an acid halide, and a step of concentrating the obtained water-immiscible organic solvent solution.
Method for producing acid halide solution, mixed solution, and method for producing monoester compound
The present disclosure provides a method for producing an acid halide solution that is useful as a production intermediate or the like that allows industrially advantageous production of a polymerizable liquid crystal compound. The method for producing an acid halide solution of the present disclosure includes a step of reacting a halogenating agent and a dicarboxylic acid compound in a water-immiscible organic solvent in the presence of a tetraalkylammonium salt to obtain a water-immiscible organic solvent solution including an acid halide, and a step of concentrating the obtained water-immiscible organic solvent solution.
NOVEL NAMPT ENZYME AGONIST AND PREPARATION AND USE THEREOF
The present invention provides a class of novel NAMPT enzyme agonist and preparation and use thereof, which has a structural formula as shown in formula I or formula II. The present invention screens the NAMPT agonist NAT from the chemical small molecule library, and the NAT exhibits a good cytoprotective effect and a good anti-neurodegeneration effect in animal models of neurodegeneration. We studied the binding of NAT to enzymes, and then carried out multiple rounds of structure optimization based on the chemical structure characteristics of NAT and its enzyme activity properties, and obtained a relatively defined structure-activity relationship. The present patent not only lays the foundation for developing innovative drugs for anti-aging and neurodegenerative diseases, but also theoretically provides a proof-of-concept that enhancing NAMPT enzyme activity plays an important role in neuroprotection.
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DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM
In a first aspect, a dicarbonyl halide includes an alicyclic group. In a second aspect, a polymer composition is derived from the dicarbonyl halide, a dianhydride and a diamine, wherein the polymer composition is a poly(amide-imide) or a poly(amide-ester-imide), wherein the poly(amide-ester-imide) is further derived from a polyol. In a third aspect, a polymer film includes the polymer composition. In a fourth aspect, an electronic device includes the polymer film. In a fifth aspect, a metal-clad laminate includes the polymer film.
DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM
In a first aspect, a dicarbonyl halide includes an alicyclic group. In a second aspect, a polymer composition is derived from the dicarbonyl halide, a dianhydride and a diamine, wherein the polymer composition is a poly(amide-imide) or a poly(amide-ester-imide), wherein the poly(amide-ester-imide) is further derived from a polyol. In a third aspect, a polymer film includes the polymer composition. In a fourth aspect, an electronic device includes the polymer film. In a fifth aspect, a metal-clad laminate includes the polymer film.
Aminated lignin-derived compounds and uses thereof
The present invention relates to novel lignin-derived compounds and compositions comprising the same and their use as redox flow battery electrolytes. The invention further provides a method for preparing said compounds and compositions as well as a redox flow battery comprising said compounds and compositions. Additionally, an assembly for carrying out the inventive method is provided.
Aminated lignin-derived compounds and uses thereof
The present invention relates to novel lignin-derived compounds and compositions comprising the same and their use as redox flow battery electrolytes. The invention further provides a method for preparing said compounds and compositions as well as a redox flow battery comprising said compounds and compositions. Additionally, an assembly for carrying out the inventive method is provided.
Aminated lignin-derived compounds and uses thereof
The present invention relates to novel lignin-derived compounds and compositions comprising the same and their use as redox flow battery electrolytes. The invention further provides a method for preparing said compounds and compositions as well as a redox flow battery comprising said compounds and compositions. Additionally, an assembly for carrying out the inventive method is provided.
PROCESS FOR THE PREPARATION OF HU-910 AND CRYSTALLINE STRUCTURE THEREOF
The invention provides processes for the preparation of HU-910, which are scalable to industrial purposes, using safer reagents and having high yield and pure product and a crystalline structure of HU-910, which is a unique product thereof.