A01N57/18

Methods for Making L-Glufosinate

Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.

Methods for the Inhibition and Dispersal of Biofilms
20180020669 · 2018-01-25 ·

The present disclosure relates to methods for inhibiting microbial growth, inhibiting biofilm formation or development, disrupting existing biofilms, reducing the biomass of a biofilm, and methods for sensitizing a biofilm and microorganisms with the biofilm to an antimicrobial agent.

Methods for the Inhibition and Dispersal of Biofilms
20180020669 · 2018-01-25 ·

The present disclosure relates to methods for inhibiting microbial growth, inhibiting biofilm formation or development, disrupting existing biofilms, reducing the biomass of a biofilm, and methods for sensitizing a biofilm and microorganisms with the biofilm to an antimicrobial agent.

Methods for the Inhibition and Dispersal of Biofilms
20180020669 · 2018-01-25 ·

The present disclosure relates to methods for inhibiting microbial growth, inhibiting biofilm formation or development, disrupting existing biofilms, reducing the biomass of a biofilm, and methods for sensitizing a biofilm and microorganisms with the biofilm to an antimicrobial agent.

Methods for making L-glufosinate

Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.

Methods for making L-glufosinate

Methods for the production of L-glufosinate (also known as phosphinothricin or (S)-2-amino-4-(hydroxy(methyl)phosphonoyl)butanoic acid) are provided. The methods comprise a two-step process. The first step involves the oxidative deamination of D-glufosinate to PPO (2-oxo-4-(hydroxy(methyl)phosphinoyl)butyric acid). The second step involves the specific amination of PPO to L-glufosinate, using an amine group from one or more amine donors. By combining these two reactions, the proportion of L-glufosinate in a mixture of L-glufosinate and D-glufosinate can be substantially increased.

Stable, concentrated herbicidal compositions
09675063 · 2017-06-13 · ·

A liquid herbicidal composition is provided, comprising: a. 20 to 35 percent by weight, based on the total weight of the composition, of a water-soluble herbicidal ingredient; b. a C.sub.12-C.sub.16 alkyl ether sulfate; c. an organic solvent; and d. an alkyl polyglucoside.
The composition is stable; i.e., it occurs in a substantially continuous, single phase at temperatures as low as 20 C. It also has a viscosity of no more than 2000 cps at temperatures as low as 0 C.

Alkoxylated alkylamine quaternary surfactants for glyphosate

The present invention relates to stable glyphosate formulations with improved efficacy by a highly effective alkoxylated alkylamine quaternary surfactant at a very low used level. The alkoxylated alkylamine quaternary surfactant is compatible in all salts of glyphosate formulations (including potassium and ammonium) even at very high concentration (470-600 g a.e./l).

Compounds for inhibiting 1-deoxy-D-xylulose-5-phosphate reductoisomerase

In particular, the compound is effective to inhibit Dxr in Mycobacterium tuberculosis (Mtb). The present invention relates to compounds having general formula (I) or (II) ##STR00001## where X is an acidic group, such as carboxylate, phosphonate, sulfate, and tetrazole; Ar is a substituted or unsubstituted aromatic or heteroaromatic group; and n is 0, 1, 2, 3, or 4, preferably 2, 3, or 4. The compounds inhibits 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr), particularly Dxr in Mycobacterium tuberculosis (Mtb).

Compounds for inhibiting 1-deoxy-D-xylulose-5-phosphate reductoisomerase

In particular, the compound is effective to inhibit Dxr in Mycobacterium tuberculosis (Mtb). The present invention relates to compounds having general formula (I) or (II) ##STR00001## where X is an acidic group, such as carboxylate, phosphonate, sulfate, and tetrazole; Ar is a substituted or unsubstituted aromatic or heteroaromatic group; and n is 0, 1, 2, 3, or 4, preferably 2, 3, or 4. The compounds inhibits 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr), particularly Dxr in Mycobacterium tuberculosis (Mtb).