Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins.

Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins.

The present disclosure relates to crystalline forms of N-{3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-allylidene}-aminoguanidinium salts having high solubility. The disclosure also relates to use of said crystalline forms in medicine.

The invention relates to a method for degradation of plastic materials into terephthalic acid (TPA) and/or ethylene glycol and/or other monomers that form the plastic materials.

The invention relates to a method for degradation of plastic materials into terephthalic acid (TPA) and/or ethylene glycol and/or other monomers that form the plastic materials.

Provided is a method for purifying organic acids, comprising: a first extraction, comprising separating an aqueous solution of organic acids into a first organic layer and a first aqueous solution layer by adding a solvent containing an amine and an alcohol; removing the alcohol from the separated first organic layer; and a second extraction, comprising separating the first organic layer from which the alcohol has been removed into a second organic layer and a second aqueous solution layer by adding water.

Provided is a method for purifying organic acids, comprising: a first extraction, comprising separating an aqueous solution of organic acids into a first organic layer and a first aqueous solution layer by adding a solvent containing an amine and an alcohol; removing the alcohol from the separated first organic layer; and a second extraction, comprising separating the first organic layer from which the alcohol has been removed into a second organic layer and a second aqueous solution layer by adding water.

A method of making a cobalt compound for feed supplements includes the steps of dissolving cobalt acetate tetrahydrate in water to form a mixture, adding an acid to the mixture, sonicating the mixture for a selected time, removing acetic acid from the mixture, and separating crystals of the cobalt compound from the mixture.

A method of making a cobalt compound for feed supplements includes the steps of dissolving cobalt acetate tetrahydrate in water to form a mixture, adding an acid to the mixture, sonicating the mixture for a selected time, removing acetic acid from the mixture, and separating crystals of the cobalt compound from the mixture.

A method of synthesizing anhydrous lactic acid is provided by reacting a compound of formula (Ia): with an acid compound of formula H.sub.nX in a first solvent to produce a reaction mixture comprising a compound of formula (Ib) and a lactic acid compound of formula (I) in solution with the first solvent and/or water. n is an integer other than 0, x is 0, or an integer other than 0, M is an alkali metal or alkaline earth metal and X is the conjugate base of the acid compound of formula H.sub.nX. The resulting reaction mixture is filtered to produce a filtrate containing lactic acid in solution. The filtrate is crystalized from a second solvent to produce anhydrous lactic acid.

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