4-Aralkylphenols and derivatives thereof expressed by general formulas (6) and (7) are useful for producing trisphenols. ##STR00001##

An aim of the present disclosure is to provide a method for producing a fluoroalkoxide, said method being more useful than conventional methods, and the like. The aim can be achieved by a method for producing a compound represented by the following formula (1): ##STR00001##
(wherein R.sup.1 is a fluoroalkyl group optionally containing an oxygen atom between carbon atoms, or a fluoroalkoxy group optionally containing an oxygen atom between carbon atoms, and
each R.sup.2 is identical to or different from each other and is a hydrocarbon group),
the method comprising the step of reacting a compound represented by the following formula (2): ##STR00002## with a compound represented by the following formula (3):
.sup.F.sup.NR.sup.2).sub.4(3).

An aim of the present disclosure is to provide a method for producing a fluoroalkoxide, said method being more useful than conventional methods, and the like. The aim can be achieved by a method for producing a compound represented by the following formula (1): ##STR00001##
(wherein R.sup.1 is a fluoroalkyl group optionally containing an oxygen atom between carbon atoms, or a fluoroalkoxy group optionally containing an oxygen atom between carbon atoms, and
each R.sup.2 is identical to or different from each other and is a hydrocarbon group),
the method comprising the step of reacting a compound represented by the following formula (2): ##STR00002## with a compound represented by the following formula (3):
.sup.F.sup.NR.sup.2).sub.4(3).

A cationic lipid compound, a preparation method and a use thereof, and a delivery system for mRNA are provided. The cationic lipid compound has a structure represented by formula (I):

##STR00001##

In formula (I): X is O or N; n is 2-4; m is 2-4; a is 0 or 1; R.sub.1 is a chain structure comprising a tertiary amine; R.sub.2 is a linear fatty acyl group or a branched chain fatty acyl group; R.sub.3 is a branched chain fatty acyl group. The cationic lipid compound is used for preparing a delivery system for mRNA.

A cationic lipid compound, a preparation method and a use thereof, and a delivery system for mRNA are provided. The cationic lipid compound has a structure represented by formula (I):

##STR00001##

In formula (I): X is O or N; n is 2-4; m is 2-4; a is 0 or 1; R.sub.1 is a chain structure comprising a tertiary amine; R.sub.2 is a linear fatty acyl group or a branched chain fatty acyl group; R.sub.3 is a branched chain fatty acyl group. The cationic lipid compound is used for preparing a delivery system for mRNA.

Methods are provided for the synthesis of cannabinoids, including cannabidiol (CBD), cannabinol (CBN), cannabichromene (CBC), cannabidiolic acid (CBDA), cannabigerol (CBG), cannabigerolic acid (CBGA), cannabidivarin (CBDV), cannabidibutol (CBD-C4), dihydrocannabidiol (DCBD), tetrahydrocannabivarin (THCV), analogs thereof, and precursors to the foregoing. One method employs phloroglucinol or a phloroglucinol analog as a starting material. The syntheses are stereospecific, efficient, selective, and cost-effective, with little or no potential for generation of THC (()-trans-.sup.9-tetrahydro-cannabinol) or any other psychoactive side product. Telescoped syntheses are also provided, as are new cannabinoids, pharmaceutical formulations, and methods of use.

Methods are provided for the synthesis of cannabinoids, including cannabidiol (CBD), cannabinol (CBN), cannabichromene (CBC), cannabidiolic acid (CBDA), cannabigerol (CBG), cannabigerolic acid (CBGA), cannabidivarin (CBDV), cannabidibutol (CBD-C4), dihydrocannabidiol (DCBD), tetrahydrocannabivarin (THCV), analogs thereof, and precursors to the foregoing. One method employs phloroglucinol or a phloroglucinol analog as a starting material. The syntheses are stereospecific, efficient, selective, and cost-effective, with little or no potential for generation of THC (()-trans-.sup.9-tetrahydro-cannabinol) or any other psychoactive side product. Telescoped syntheses are also provided, as are new cannabinoids, pharmaceutical formulations, and methods of use.

An aim of the present disclosure is to provide a method for producing a fluoroalkoxide, said method being more useful than conventional methods, and the like. The aim can be achieved by a method for producing a compound represented by the following formula (1):

##STR00001## (wherein R.sup.1 is a fluoroalkyl group optionally containing an oxygen atom between carbon atoms, or a fluoroalkoxy group optionally containing an oxygen atom between carbon atoms, and each R.sup.2 is identical to or different from each other and is a hydrocarbon group), the method comprising the step of reacting a compound represented by the following formula (2):

##STR00002## with a compound represented by the following formula (3):

##STR00003##

An aim of the present disclosure is to provide a method for producing a fluoroalkoxide, said method being more useful than conventional methods, and the like. The aim can be achieved by a method for producing a compound represented by the following formula (1):

##STR00001## (wherein R.sup.1 is a fluoroalkyl group optionally containing an oxygen atom between carbon atoms, or a fluoroalkoxy group optionally containing an oxygen atom between carbon atoms, and each R.sup.2 is identical to or different from each other and is a hydrocarbon group), the method comprising the step of reacting a compound represented by the following formula (2):

##STR00002## with a compound represented by the following formula (3):

##STR00003##

##STR00001##

The present invention relates to a method for preparing 4-hydroxy-2-methylene-butanal, 4-hydroxy-2-methyl-but-2-enal and esters thereof of the formula (I.a) and (I.b) where R.sup.1 is as defined in the claims and the description, by subjecting isoprenol or an ester thereof to a photooxidation in the presence of a photosensitizer and an acylating agent. The invention relates moreover to certain hydroperoxides of the compounds (I.a) or (I.b), and to the use thereof as intermediates in the synthesis of compounds (I.a) and (I.b) or in the synthesis of retinol, stereoisomers and derivatives thereof.