A process to form a composition comprising an asymmetrical polyene, the asymmetrical polyene comprising an “α,β unsaturated-carbonyl end” and a “C—C double bond end,” the process comprising: reacting an alkene- or polyene-containing alcohol with an alkyl ester of an α,β unsaturated carboxylic acid in the presence of at least the following components A) through C) to form a solution comprising an asymmetrical polyene: A) a lithium salt; B) a component selected from the group consisting of hydroquinone, an alkyl-substituted phenol, a substituted alkyl-substituted phenol, an alkyl-substituted hydroquinone, a substituted alkyl-substituted hydroquinone, and combinations thereof; and C) an N-oxyl-containing compound; wherein the “α,β unsaturated-carbonyl end” of the asymmetrical polyene is selected from the group consisting of structures a) through c), as described herein, and wherein the “C—C double bond end” of the asymmetrical polyene is selected from the group consisting of structures 1) through 17), as described herein.

A process to form a composition comprising an asymmetrical polyene, the asymmetrical polyene comprising an “α,β unsaturated-carbonyl end” and a “C—C double bond end,” the process comprising: reacting an alkene- or polyene-containing alcohol with an alkyl ester of an α,β unsaturated carboxylic acid in the presence of at least the following components A) through C) to form a solution comprising an asymmetrical polyene: A) a lithium salt; B) a component selected from the group consisting of hydroquinone, an alkyl-substituted phenol, a substituted alkyl-substituted phenol, an alkyl-substituted hydroquinone, a substituted alkyl-substituted hydroquinone, and combinations thereof; and C) an N-oxyl-containing compound; wherein the “α,β unsaturated-carbonyl end” of the asymmetrical polyene is selected from the group consisting of structures a) through c), as described herein, and wherein the “C—C double bond end” of the asymmetrical polyene is selected from the group consisting of structures 1) through 17), as described herein.

Polyol esters of metathesized fatty acids are generally disclosed herein. Methods of using such compounds, for example, as cleaning agents, solvents, and coalescents for paints and coatings, are also disclosed.

Polyol esters of metathesized fatty acids are generally disclosed herein. Methods of using such compounds, for example, as cleaning agents, solvents, and coalescents for paints and coatings, are also disclosed.

The present invention relates to the fibric acid derivatives of omega-3 fatty acids and their use in treating Type2 diabetes, obesity, hypertriglyceridemia, cardiovascular diseases, metabolic syndrome, cancer, Alzheimer's disease; and their use for modulating activity of peroxisome proliferator-activated receptors (PPARs).

The present invention relates to the fibric acid derivatives of omega-3 fatty acids and their use in treating Type2 diabetes, obesity, hypertriglyceridemia, cardiovascular diseases, metabolic syndrome, cancer, Alzheimer's disease; and their use for modulating activity of peroxisome proliferator-activated receptors (PPARs).

The disclosures herein provide compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These compounds may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, intravenous, spray, parenteral, lozenge, solution, syrup, sachet, transdermal administration, or injection. Such compositions may be used to treatment of inflammation or its associated complications.

The disclosures herein provide compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These compounds may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, intravenous, spray, parenteral, lozenge, solution, syrup, sachet, transdermal administration, or injection. Such compositions may be used to treatment of inflammation or its associated complications.

The present invention discloses a method for recycling urea in the process of separating and purifying unsaturated substances through a urea adduction method. The method comprises the following steps: liposoluble substances containing target unsaturated components are used as raw materials, and subjected to urea adduction, crystallization and filtration to produce a filtrate, from which the specific unsaturated components are obtained; the urea adduct is dissolved in a polar solvent, and after the adducted adducts are layered and released, adding a certain solvent to the urea solution to adjust the polarity, then cooling for crystallization, and recycling the urea. The method can realize complete release of the adducted components and recycling and reuse of urea, and the process is simple, the recovery rate is high, and the adduction effect is not influenced when recycling urea for reuse, and the production cost of the urea adduct is reduced, thus alleviating the adverse impact of urea discharges on the environment.

The present invention discloses a method for recycling urea in the process of separating and purifying unsaturated substances through a urea adduction method. The method comprises the following steps: liposoluble substances containing target unsaturated components are used as raw materials, and subjected to urea adduction, crystallization and filtration to produce a filtrate, from which the specific unsaturated components are obtained; the urea adduct is dissolved in a polar solvent, and after the adducted adducts are layered and released, adding a certain solvent to the urea solution to adjust the polarity, then cooling for crystallization, and recycling the urea. The method can realize complete release of the adducted components and recycling and reuse of urea, and the process is simple, the recovery rate is high, and the adduction effect is not influenced when recycling urea for reuse, and the production cost of the urea adduct is reduced, thus alleviating the adverse impact of urea discharges on the environment.