C07C69/604

MONOMETHYL FUMARATE PRECURSOR DRUG COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF
20210387939 · 2021-12-16 ·

The present invention provides: novel compounds capable of producing monomethyl fumarate after the compounds are administered; pharmaceutical compositions comprising same as active ingredients; and pharmaceutical uses thereof for treating or alleviating various diseases including immune system abnormalities, neurodegeneration, and/or inflammatory diseases.

Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used

The compound is represented by general formula (i). In the compound, in a group K.sup.i1, at least two secondary carbon atoms in an alkyl group (a linear alkyl, halogenated alkyl, or cyanogenated alkyl group having 3 to 40 carbon atoms) are replaced with —C(═X.sup.i1)— and/or —CH(—CN)—, where X.sup.i1 is an oxygen atom, a sulfur atom, NH, or NR.sup.13; in addition, a group A.sup.i2, a group A.sup.i3, or the group K.sup.i1 includes, as a substituent, at least one P.sup.i1-Sp.sup.i1- group, where P.sup.i1 is a polymerizable group, and SP.sup.i1 is a spacer group or a single bond. The liquid crystal composition including the compound represented by general formula (i) can be adsorbed onto substrates between which a liquid crystal layer is held, and, consequently, without the use of an alignment film, liquid crystal molecules can be maintained in a state in which the liquid crystal molecules are aligned in a vertical direction. ##STR00001##

Polymerizable compound, and liquid crystal composition and liquid crystal display element in which the compound is used

The compound is represented by general formula (i). In the compound, in a group K.sup.i1, at least two secondary carbon atoms in an alkyl group (a linear alkyl, halogenated alkyl, or cyanogenated alkyl group having 3 to 40 carbon atoms) are replaced with —C(═X.sup.i1)— and/or —CH(—CN)—, where X.sup.i1 is an oxygen atom, a sulfur atom, NH, or NR.sup.13; in addition, a group A.sup.i2, a group A.sup.i3, or the group K.sup.i1 includes, as a substituent, at least one P.sup.i1-Sp.sup.i1- group, where P.sup.i1 is a polymerizable group, and SP.sup.i1 is a spacer group or a single bond. The liquid crystal composition including the compound represented by general formula (i) can be adsorbed onto substrates between which a liquid crystal layer is held, and, consequently, without the use of an alignment film, liquid crystal molecules can be maintained in a state in which the liquid crystal molecules are aligned in a vertical direction. ##STR00001##

Increasing the content of long chain fatty acids in seed oil

Provided are plants that express, or overexpress, a pPLAIIIδ protein. Constitutive or seed-specific expression of pPLAIIIδ protein in Arabidopsis increases seed oil content, the amount of C20 and C22 fatty acids, and the amount of C56, C58, and C60 triacylglycerols, effectively resulting in significantly higher oil yield per plant. Use of pPLAIIIδ is therefore an effective biotechnological tool to significantly increase plant yield, including oil, and the amount of high value long chain fatty acids in agricultural and horticultural crops, especially oilseed crops.

Increasing the content of long chain fatty acids in seed oil

Provided are plants that express, or overexpress, a pPLAIIIδ protein. Constitutive or seed-specific expression of pPLAIIIδ protein in Arabidopsis increases seed oil content, the amount of C20 and C22 fatty acids, and the amount of C56, C58, and C60 triacylglycerols, effectively resulting in significantly higher oil yield per plant. Use of pPLAIIIδ is therefore an effective biotechnological tool to significantly increase plant yield, including oil, and the amount of high value long chain fatty acids in agricultural and horticultural crops, especially oilseed crops.

BIODEGRADABLE LUBRICANT WITH TAILORED HYDROLYTIC STABILITY AND IMPROVED THERMAL STABILITY THROUGH ALKOXYLATION OF GLYCEROL

Described herein are methods of stabilizing the beta hydrogen of glycerol based esters by the insertion of alkoxy groups to significantly improve the thermal, oxidative, and hydrolytic stability of the ester and allow for controlling the molar density of esters bonds in the lubricants to maximize hydrolytic stability while maintaining biodegradability and further improving performance properties.

BIODEGRADABLE LUBRICANT WITH TAILORED HYDROLYTIC STABILITY AND IMPROVED THERMAL STABILITY THROUGH ALKOXYLATION OF GLYCEROL

Described herein are methods of stabilizing the beta hydrogen of glycerol based esters by the insertion of alkoxy groups to significantly improve the thermal, oxidative, and hydrolytic stability of the ester and allow for controlling the molar density of esters bonds in the lubricants to maximize hydrolytic stability while maintaining biodegradability and further improving performance properties.

Use of renewable oil in hydrotreatment process
11421160 · 2022-08-23 · ·

The use of bio oil from at least one renewable source in a hydrotreatment process, in which process hydrocarbons are formed from said glyceride oil in a catalytic reaction, and the iron content of said bio oil is less than 1 w-ppm calculated as elemental iron. A bio oil intermediate including bio oil from at least one renewable source and the iron content of said bio oil is less than 1 w-ppm calculated as elemental iron.

Use of renewable oil in hydrotreatment process
11421160 · 2022-08-23 · ·

The use of bio oil from at least one renewable source in a hydrotreatment process, in which process hydrocarbons are formed from said glyceride oil in a catalytic reaction, and the iron content of said bio oil is less than 1 w-ppm calculated as elemental iron. A bio oil intermediate including bio oil from at least one renewable source and the iron content of said bio oil is less than 1 w-ppm calculated as elemental iron.

Use of renewable oil in hydrotreatment process
11414605 · 2022-08-16 · ·

The use of bio oil from at least one renewable source in a hydrotreatment process, in which process hydrocarbons are formed from said glyceride oil in a catalytic reaction, and the iron content of said bio oil is less than 1 w-ppm calculated as elemental iron. A bio oil intermediate including bio oil from at least one renewable source and the iron content of said bio oil is less than 1 w-ppm calculated as elemental iron.