It is an objective of the present invention to provide a novel polymerizable triptycene derivative and a polymer compound as constituent component thereof that has a structure in which three benzene rings arranged at the axis formed by barrelene of the triptycene skeleton can rotate evenly and that has hydrophilicity imparted to it as compared to any of the prior art triptycene derivatives and is thus highly useful in functional materials.

The above objective is achieved by the polymerizable triptycene derivative and a polymer compound as constituent component thereof having substituents with an unsaturated bonding functional group at position 9 and/or position 10 of the triptycene skeleton, the polymerizable triptycene derivative having two carboxyl groups and the polymerizable triptycene derivative having one carboxyl group and one amino group.

It is an objective of the present invention to provide a novel polymerizable triptycene derivative and a polymer compound as constituent component thereof that has a structure in which three benzene rings arranged at the axis formed by barrelene of the triptycene skeleton can rotate evenly and that has hydrophilicity imparted to it as compared to any of the prior art triptycene derivatives and is thus highly useful in functional materials.

The above objective is achieved by the polymerizable triptycene derivative and a polymer compound as constituent component thereof having substituents with an unsaturated bonding functional group at position 9 and/or position 10 of the triptycene skeleton, the polymerizable triptycene derivative having two carboxyl groups and the polymerizable triptycene derivative having one carboxyl group and one amino group.

The disclosures herein provide compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These compounds may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, intravenous, spray, parenteral, lozenge, solution, syrup, sachet, transdermal administration, or injection. Such compositions may be used to treatment of inflammation or its associated complications.

The disclosures herein provide compounds of formula I or its pharmaceutical acceptable salts, as well as polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These compounds may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, intravenous, spray, parenteral, lozenge, solution, syrup, sachet, transdermal administration, or injection. Such compositions may be used to treatment of inflammation or its associated complications.

The present invention relates novel methods of synthesizing terphenyl compounds and in particular to novel methods for the synthesis of a compound of Formula I or intermediates thereof. ##STR00001##

The present invention relates novel methods of synthesizing terphenyl compounds and in particular to novel methods for the synthesis of a compound of Formula I or intermediates thereof. ##STR00001##

A thermochromic pigment composition including compounds of formula (I):

##STR00001##

in which: X represents CHR.sub.2, O, OCO or CHCH; Y represents O, COO, or OCOO; R.sub.1 represents H or (CH.sub.2).sub.pCH.sub.3; R.sub.2 represents phenyl or H; m=12-18; n=0-14; p=12-18; and on the condition that, if n=0, X represents CHR.sub.2 or CHCH.

The thermochromic pigment compositions having compounds of formula (I), include thermochromic pigment microcapsules. The thermochromic pigment capsules are useable for thermochromic pigment compositions in ink which may be used writing instruments.

A thermochromic pigment composition including compounds of formula (I):

##STR00001##

in which: X represents CHR.sub.2, O, OCO or CHCH; Y represents O, COO, or OCOO; R.sub.1 represents H or (CH.sub.2).sub.pCH.sub.3; R.sub.2 represents phenyl or H; m=12-18; n=0-14; p=12-18; and on the condition that, if n=0, X represents CHR.sub.2 or CHCH.

The thermochromic pigment compositions having compounds of formula (I), include thermochromic pigment microcapsules. The thermochromic pigment capsules are useable for thermochromic pigment compositions in ink which may be used writing instruments.

The present invention addresses the problem of providing a novel chemically activated water-soluble prodrug. The present invention provides a compound represented by formula (1), or a pharmacologically acceptable salt thereof (in the formula, A represents A-0; X.sup.1 and X.sup.2 are the same as or different from each other and each independently represent a hydroxyl group or OC(O)Y(C(R.sup.1A) (R.sup.1B))n-NHR.sup.2, where X.sup.1 and X.sup.2 are not simultaneously hydroxyl groups, n is 2, 3, or 4, Y represents an oxygen atom or NR.sup.4, R.sup.1A and R.sup.1B are the same as or different from each other and each independently represent a hydrogen atom, etc., and R.sup.2 represents a hydrogen atom, etc.; and R.sup.a to R.sup.d are optionally present, are the same as or different from each other, and each independently represent a hydrogen atom, etc.).

The present invention addresses the problem of providing a novel chemically activated water-soluble prodrug. The present invention provides a compound represented by formula (1), or a pharmacologically acceptable salt thereof (in the formula, A represents A-0; X.sup.1 and X.sup.2 are the same as or different from each other and each independently represent a hydroxyl group or OC(O)Y(C(R.sup.1A) (R.sup.1B))n-NHR.sup.2, where X.sup.1 and X.sup.2 are not simultaneously hydroxyl groups, n is 2, 3, or 4, Y represents an oxygen atom or NR.sup.4, R.sup.1A and R.sup.1B are the same as or different from each other and each independently represent a hydrogen atom, etc., and R.sup.2 represents a hydrogen atom, etc.; and R.sup.a to R.sup.d are optionally present, are the same as or different from each other, and each independently represent a hydrogen atom, etc.).