Patent classifications
C07C205/19
Monocarbonyl ruthenium and osmium catalysts
The invention relates to monocarbonyl complexes of ruthenium and osmium with bi- and tridentate nitrogen and phosphine ligands. The invention relates to methods for preparing these complexes and the use of these complexes, isolated or prepared in situ, as catalysts for reduction reactions of ketones and aldehydes both via transfer hydrogenation or hydrogenation with hydrogen.
Monocarbonyl ruthenium and osmium catalysts
The invention relates to monocarbonyl complexes of ruthenium and osmium with bi- and tridentate nitrogen and phosphine ligands. The invention relates to methods for preparing these complexes and the use of these complexes, isolated or prepared in situ, as catalysts for reduction reactions of ketones and aldehydes both via transfer hydrogenation or hydrogenation with hydrogen.
Process for Manufacturing Pibrentasvir Active Drug Substance
The present invention relates to compositions of pibrentasvir, drug products thereof, and processes and intermediates for the preparation thereof. This invention relates to the drug product, active drug substance, intermediates, and processes of pibrentasvir, a NS5A inhibitor that is useful in the treatment of hepatitis C.
Process for Manufacturing Pibrentasvir Active Drug Substance
The present invention relates to compositions of pibrentasvir, drug products thereof, and processes and intermediates for the preparation thereof. This invention relates to the drug product, active drug substance, intermediates, and processes of pibrentasvir, a NS5A inhibitor that is useful in the treatment of hepatitis C.
Process for Manufacturing Pibrentasvir Active Drug Substance
The present invention relates to compositions of pibrentasvir, drug products thereof, and processes and intermediates for the preparation thereof. This invention relates to the drug product, active drug substance, intermediates, and processes of pibrentasvir, a NS5A inhibitor that is useful in the treatment of hepatitis C.
Highly efficient nanosized mesoporous CuMgAl ternary oxide catalyst
Highly efficient nanosized mesoporous CuMgAl ternary oxide catalysts are provided.
Highly efficient nanosized mesoporous CuMgAl ternary oxide catalyst
Highly efficient nanosized mesoporous CuMgAl ternary oxide catalysts are provided.
DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS
The disclosure relates to dicarbonyl complexes of ruthenium and osmium with bi- and tridentate nitrogen and phosphine ligands. The disclosure relates to methods for preparing these complexes and the use of these complexes, isolated or prepared in situ, as catalysts for reduction reactions of ketones and aldehydes both via transfer hydrogenation or hydrogenation with hydrogen.
DICARBONYL RUTHENIUM AND OSMIUM CATALYSTS
The disclosure relates to dicarbonyl complexes of ruthenium and osmium with bi- and tridentate nitrogen and phosphine ligands. The disclosure relates to methods for preparing these complexes and the use of these complexes, isolated or prepared in situ, as catalysts for reduction reactions of ketones and aldehydes both via transfer hydrogenation or hydrogenation with hydrogen.
METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES
The invention provides novel methods for preparing indolinobenzodiazepine dimer compounds and their synthetic precursors.