C07C209/70

PROCESSES FOR PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES

A process for preparation of 4-aminoindane derivatives of a first formula, salts and enantiomers thereof comprising the steps of: a) hydrogenating a 1,2-dihydroquinoline of a second formula to give a corresponding tetrahydroquinoline of a third formula; b) acylating the tetrahydroquinoline of the third formula with a carboxylic acid derivative of a fourth formula to obtain a corresponding acyl derivative compound of a fifth formula; c) rearranging the acyl derivative compound of the fifth formula under acidic conditions so as to give an acyl indane compound of a sixth formula; and d) hydrolysing the acyl group of the acyl indane compound of the sixth formula so as to obtain the 4-aminoindane derivatives of the first formula.

Ruthenium-based triazole carbene complexes

The present invention relates to novel ruthenium-based triazole carbene complexes comprising specific ligands, their preparation and their use as catalysts in hydrogenation processes. Such complex catalysts are inexpensive, thermally robust, gel formation inhibiting and olefin selective.

Ruthenium-based triazole carbene complexes

The present invention relates to novel ruthenium-based triazole carbene complexes comprising specific ligands, their preparation and their use as catalysts in hydrogenation processes. Such complex catalysts are inexpensive, thermally robust, gel formation inhibiting and olefin selective.

Ruthenium-based triazole carbene complexes

The present invention relates to novel ruthenium-based triazole carbene complexes comprising specific ligands, their preparation and their use as catalysts in hydrogenation processes. Such complex catalysts are inexpensive, thermally robust, gel formation inhibiting and olefin selective.

PROCESS FOR CONVERTING S-ENANTIOMER TO ITS RACEMIC FORM
20190092716 · 2019-03-28 ·

The present invention relates to a novel process for converting the unwanted S enantiomer form to its useful raceme with respect to a 4-aminoindane derivative.

PROCESS FOR CONVERTING S-ENANTIOMER TO ITS RACEMIC FORM
20190092716 · 2019-03-28 ·

The present invention relates to a novel process for converting the unwanted S enantiomer form to its useful raceme with respect to a 4-aminoindane derivative.

Methods of making compounds having antidegradant and antifatigue efficacy

A method of making antidegradant compounds is disclosed, in which a p-phenylenediamine is reacted with an alpha-hydroxy carbonyl compound to thereby obtain an enediamine, which is reduced to thereby obtain a mixture comprising the antidegradant compound.

Methods of making compounds having antidegradant and antifatigue efficacy

A method of making antidegradant compounds is disclosed, in which a p-phenylenediamine is reacted with an alpha-hydroxy carbonyl compound to thereby obtain an enediamine, which is reduced to thereby obtain a mixture comprising the antidegradant compound.

Methods of making compounds having antidegradant and antifatigue efficacy

A method of making antidegradant compounds is disclosed, in which a p-phenylenediamine is reacted with an alpha-hydroxy carbonyl compound to thereby obtain an enediamine, which is reduced to thereby obtain a mixture comprising the antidegradant compound.

NEW METHOD FOR SYNTHESIS OF FENFLURAMINE, AND NEW COMPOSITIONS COMPRISING IT
20180208543 · 2018-07-26 · ·

A new process for preparing the fenfluramine molecule and new compositions containing fenfluramine obtainable with the claimed process.