Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, in the presence of hydrogen, a nitrogen-containing compound, and a catalyst, wherein the presence of the nitrogen-containing compound, expressed in a molar ratio relative to the first functional group in the organic feed substrate, at least during the reaction as long as the conversion of the organic feed substrate has not yet reached 80%, is maintained below a level of 1.3. Further disclosed is a composition of the invention comprising at least 98.0% wt of 2-chloro-benzyl-dimethylamine, at most 0.60% wt of the meso-o-Cl-BDMA dimer and at least 1 ppm wt of the (+/)-o-Cl-BDMA dimer and any use therefor.

The invention relates to a production process for di- and polyamines of the diphenylmethane series by the rearrangement of a condensation product of aniline and a methylene group-supplying agent preferably selected from the group consisting of aqueous formaldehyde solution, gaseous formaldehyde, para-formaldehyde, trioxane and mixtures thereof, wherein said condensation product is reacted in the presence of at least one silica-alumina catalyst, said catalyst having a surface area as determined by the BET method carried out according to ASTM D3663-03 (2015) of from 200 m.sup.2/g to 520 m.sup.2/g, preferably of from 350 m.sup.2/g to 495 m.sup.2/g, particularly preferably of from 400 m.sup.2/g to 490 m.sup.2/g, a molar ratio of silica/alumina on the catalyst surface of A, an overall (bulk) molar ratio of silica/alumina of C, and a quotient B=A/C;
said catalyst being characterised in that low A values (i.e. equal to or lower than 8.0) are combined with high B values (i.e. of from 1.50 to 3.00), and high A values (i.e. larger than 8.00, especially equal to or larger than 8.50) are combined with low B values (i.e. of from 0.15 to 1.40).

The invention relates to a production process for di- and polyamines of the diphenylmethane series by the rearrangement of a condensation product of aniline and a methylene group-supplying agent preferably selected from the group consisting of aqueous formaldehyde solution, gaseous formaldehyde, para-formaldehyde, trioxane and mixtures thereof, wherein said condensation product is reacted in the presence of at least one silica-alumina catalyst, said catalyst having a surface area as determined by the BET method carried out according to ASTM D3663-03 (2015) of from 200 m.sup.2/g to 520 m.sup.2/g, preferably of from 350 m.sup.2/g to 495 m.sup.2/g, particularly preferably of from 400 m.sup.2/g to 490 m.sup.2/g, a molar ratio of silica/alumina on the catalyst surface of A, an overall (bulk) molar ratio of silica/alumina of C, and a quotient B=A/C;
said catalyst being characterised in that low A values (i.e. equal to or lower than 8.0) are combined with high B values (i.e. of from 1.50 to 3.00), and high A values (i.e. larger than 8.00, especially equal to or larger than 8.50) are combined with low B values (i.e. of from 0.15 to 1.40).

The invention relates to a production process for di- and polyamines of the diphenylmethane series by the rearrangement of a condensation product of aniline and a methylene group-supplying agent preferably selected from the group consisting of aqueous formaldehyde solution, gaseous formaldehyde, para-formaldehyde, trioxane and mixtures thereof, wherein said condensation product is reacted in the presence of at least one silica-alumina catalyst, said catalyst having a surface area as determined by the BET method carried out according to ASTM D3663-03 (2015) of from 200 m.sup.2/g to 520 m.sup.2/g, preferably of from 350 m.sup.2/g to 495 m.sup.2/g, particularly preferably of from 400 m.sup.2/g to 490 m.sup.2/g, a molar ratio of silica/alumina on the catalyst surface of A, an overall (bulk) molar ratio of silica/alumina of C, and a quotient B=A/C;
said catalyst being characterised in that low A values (i.e. equal to or lower than 8.0) are combined with high B values (i.e. of from 1.50 to 3.00), and high A values (i.e. larger than 8.00, especially equal to or larger than 8.50) are combined with low B values (i.e. of from 0.15 to 1.40).

Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, in the presence of hydrogen, a nitrogen-containing compound, and a catalyst, wherein the presence of the nitrogen-containing compound, expressed in a molar ratio relative to the first functional group in the organic feed substrate, at least during the reaction as long as the conversion of the organic feed substrate has not yet reached 80%, is maintained below a level of 1.3. Further disclosed is a composition of the invention comprising at least 98.0% wt of 2-chloro-benzyl-dimethylamine, at most 0.60% wt of the meso-o-Cl-BDMA dimer and at least 1 ppm wt of the (+/)-o-Cl-BDMA dimer and any use therefor.

Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, in the presence of hydrogen, a nitrogen-containing compound, and a catalyst, wherein the presence of the nitrogen-containing compound, expressed in a molar ratio relative to the first functional group in the organic feed substrate, at least during the reaction as long as the conversion of the organic feed substrate has not yet reached 80%, is maintained below a level of 1.3. Further disclosed is a composition of the invention comprising at least 98.0% wt of 2-chloro-benzyl-dimethylamine, at most 0.60% wt of the meso-o-Cl-BDMA dimer and at least 1 ppm wt of the (+/)-o-Cl-BDMA dimer and any use therefor.

The present invention relates to a process for preparing aminobenzoic acid or an aminobenzoic acid conversion product, comprising the steps of: (I) providing an aqueous solution of aminobenzoic acid using a fermentation process; (II) adsorbing aminobenzoic acid; (III) desorbing aminobenzoic acid at a pH in the range from 0.8 to 3.0, preferably 0.5 to 3.0, more preferably 0.1 to 3.0, very preferably 0.5 to 2.5, very exceptionally preferably 1.0 to 2.0; (IV) obtaining the aminobenzoic acid from the desorbate obtained in step (III); (V) optionally further converting the aminobenzoic acid obtained in step (IV) to an aminobenzoic acid conversion product.

The present invention relates to a process for preparing aminobenzoic acid or an aminobenzoic acid conversion product, comprising the steps of: (I) providing an aqueous solution of aminobenzoic acid using a fermentation process; (II) adsorbing aminobenzoic acid; (III) desorbing aminobenzoic acid at a pH in the range from 0.8 to 3.0, preferably 0.5 to 3.0, more preferably 0.1 to 3.0, very preferably 0.5 to 2.5, very exceptionally preferably 1.0 to 2.0; (IV) obtaining the aminobenzoic acid from the desorbate obtained in step (III); (V) optionally further converting the aminobenzoic acid obtained in step (IV) to an aminobenzoic acid conversion product.

The present application provides solvent-free methods for decarboxylation of amino acids via imine formation with a ketone, enone, enal, aldehyde co-reagent or combination thereof, under heated conditions, with optional recovery of the co-reagent and/or co-reagent byproduct.

The present application provides solvent-free methods for decarboxylation of amino acids via imine formation with a ketone, enone, enal, aldehyde co-reagent or combination thereof, under heated conditions, with optional recovery of the co-reagent and/or co-reagent byproduct.