C07C209/78

Process for the reductive amination of halogen-containing substrates

Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, in the presence of hydrogen, a nitrogen-containing compound, and a catalyst, wherein the presence of the nitrogen-containing compound, expressed in a molar ratio relative to the first functional group in the organic feed substrate, at least during the reaction as long as the conversion of the organic feed substrate has not yet reached 80%, is maintained below a level of 1.3. Further disclosed is a composition of the invention comprising at least 98.0% wt of 2-chloro-benzyl-dimethylamine, at most 0.60% wt of the meso-o-Cl-BDMA dimer and at least 1 ppm wt of the (+/)-o-Cl-BDMA dimer and any use therefor.

Process for the reductive amination of halogen-containing substrates

Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, in the presence of hydrogen, a nitrogen-containing compound, and a catalyst, wherein the presence of the nitrogen-containing compound, expressed in a molar ratio relative to the first functional group in the organic feed substrate, at least during the reaction as long as the conversion of the organic feed substrate has not yet reached 80%, is maintained below a level of 1.3. Further disclosed is a composition of the invention comprising at least 98.0% wt of 2-chloro-benzyl-dimethylamine, at most 0.60% wt of the meso-o-Cl-BDMA dimer and at least 1 ppm wt of the (+/)-o-Cl-BDMA dimer and any use therefor.

Process for the reductive amination of halogen-containing substrates

Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, in the presence of hydrogen, a nitrogen-containing compound, and a catalyst, wherein the presence of the nitrogen-containing compound, expressed in a molar ratio relative to the first functional group in the organic feed substrate, at least during the reaction as long as the conversion of the organic feed substrate has not yet reached 80%, is maintained below a level of 1.3. Further disclosed is a composition of the invention comprising at least 98.0% wt of 2-chloro-benzyl-dimethylamine, at most 0.60% wt of the meso-o-Cl-BDMA dimer and at least 1 ppm wt of the (+/)-o-Cl-BDMA dimer and any use therefor.

Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material

A simple production process is provided of a perfluoroalkyl compound that uses monohydroperfluoroalkane as a starting material, the perfluoroalkyl compound being an important intermediate of organic electronic materials, medicine, agricultural chemicals, functional polymer materials and the like. With monohydroperfluoroalkane is reacted a base and then a carbonyl compound to produce an alcohol having a perfluoroalkyl group. For example, potassium hydroxide is made to interact with trifluoromethane, and a reaction with a carbonyl compound is induced to produce an alcohol having a trifluoromethyl group.

Preparation process of perfluoroalkyl compound with monohydroperfluoroalkane as starting material

A simple production process is provided of a perfluoroalkyl compound that uses monohydroperfluoroalkane as a starting material, the perfluoroalkyl compound being an important intermediate of organic electronic materials, medicine, agricultural chemicals, functional polymer materials and the like. With monohydroperfluoroalkane is reacted a base and then a carbonyl compound to produce an alcohol having a perfluoroalkyl group. For example, potassium hydroxide is made to interact with trifluoromethane, and a reaction with a carbonyl compound is induced to produce an alcohol having a trifluoromethyl group.

PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS COMPRISING AT LEAST TWO AMINE FUNCTIONS
20190292128 · 2019-09-26 ·

Provided is a process for the production of an aromatic compound comprising at least two amine functions, comprising reacting an aromatic compound having at least one hydroxyl function and at least one aldehyde function with a second reactant having an amine function, in the presence of a reductant agent and a catalyst comprising at least one metal element in elemental form and/or at least one metal oxide.

PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS COMPRISING AT LEAST TWO AMINE FUNCTIONS
20190292128 · 2019-09-26 ·

Provided is a process for the production of an aromatic compound comprising at least two amine functions, comprising reacting an aromatic compound having at least one hydroxyl function and at least one aldehyde function with a second reactant having an amine function, in the presence of a reductant agent and a catalyst comprising at least one metal element in elemental form and/or at least one metal oxide.

NEW TWIN TAIL AMINE COMPOUNDS AND THEIR ZWITTERIONIC DERIVATIVES

A compound of general formula (I) or (II), wherein R.sub.n and R.sub.m independently represent a C.sub.3-C.sub.27 aliphatic group, R.sub.1 to R.sub.4, which may be the same or different at each occurrence, represent hydrogen or a C.sub.1-C.sub.8 alkyl group, X.sub.1 and X.sub.2, which may be the same or different at each occurrence, represent a linear or branched divalent hydrocarbon radical with 1 to 24 carbon atoms which can be optionally substituted and/or interrupted by one or more heteroatoms or heteroatom containing groups, and R.sub.5 and R.sub.6, which may be the same or different at each occurrence, represent a group selected from O.sup., -Alk-CH(OH)CH.sub.2SO.sub.3 and -Alk-CO.sub.2 wherein Alk represents an alkylene group.

##STR00001##

NEW TWIN TAIL AMINE COMPOUNDS AND THEIR ZWITTERIONIC DERIVATIVES

A compound of general formula (I) or (II), wherein R.sub.n and R.sub.m independently represent a C.sub.3-C.sub.27 aliphatic group, R.sub.1 to R.sub.4, which may be the same or different at each occurrence, represent hydrogen or a C.sub.1-C.sub.8 alkyl group, X.sub.1 and X.sub.2, which may be the same or different at each occurrence, represent a linear or branched divalent hydrocarbon radical with 1 to 24 carbon atoms which can be optionally substituted and/or interrupted by one or more heteroatoms or heteroatom containing groups, and R.sub.5 and R.sub.6, which may be the same or different at each occurrence, represent a group selected from O.sup., -Alk-CH(OH)CH.sub.2SO.sub.3 and -Alk-CO.sub.2 wherein Alk represents an alkylene group.

##STR00001##

METHOD FOR PRODUCING ANILINE OR AN ANILINE CONVERSION PRODUCT

The invention relates to a method for producing aniline or products that are obtained by further chemical reaction of aniline (aniline derivatives), involving decarboxylation of aminobenzoic acid, particularly ortho-aminobenzoic acid, in which one portion of the previously formed crude aniline is recirculated in the decarboxylation step. The aminobenzoic acid is obtained enzymatically or chemically, preferably enzymatically.