C07C229/34

Pain relief compounds

The present invention relates to the use of compounds for the treatment or prevention of pain in mammals, in particularly in human beings, and also to a process for preparing these compounds.

NEW PROCESS AND INTERMEDIATES

The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new chemical synthesis route.

NEW PROCESS AND INTERMEDIATES

The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new chemical synthesis route.

Adenylyl cyclase inhibitors for neuropathic and inflammatory pain

The invention generally relates to adenylyl cyclase inhibitor compounds and methods for treating neuropathic or inflammatory pain by using those compounds.

Adenylyl cyclase inhibitors for neuropathic and inflammatory pain

The invention generally relates to adenylyl cyclase inhibitor compounds and methods for treating neuropathic or inflammatory pain by using those compounds.

?-Asary-laldehyde ester, preparation method therefor, and application thereof

The present invention relates to ?-asary-laldehyde ester. The chemical structure of the related ?-asary-laldehyde ester is of formula I.

?-Asary-laldehyde ester, preparation method therefor, and application thereof

The present invention relates to ?-asary-laldehyde ester. The chemical structure of the related ?-asary-laldehyde ester is of formula I.

5-substituted-5-hydroxy-5-aryl-3-oxo-pentanoate derivatives and their enantiopure forms

The present invention relates to novel tertiary alcohol derivatives substituted with aryl and trifluoromethyl, and optical isomers thereof. In addition, the present invention also relates to methods for the preparation and use as enantiomer recognition agent thereof. The present invention provides pharmaceutical composition and use as therapeutically active substance thereof.

5-substituted-5-hydroxy-5-aryl-3-oxo-pentanoate derivatives and their enantiopure forms

The present invention relates to novel tertiary alcohol derivatives substituted with aryl and trifluoromethyl, and optical isomers thereof. In addition, the present invention also relates to methods for the preparation and use as enantiomer recognition agent thereof. The present invention provides pharmaceutical composition and use as therapeutically active substance thereof.

5-substituted-5-hydroxy-5-aryl-3-oxo-pentanoate derivatives and their enantiopure forms

The present invention relates to novel tertiary alcohol derivatives substituted with aryl and trifluoromethyl, and optical isomers thereof. In addition, the present invention also relates to methods for the preparation and use as enantiomer recognition agent thereof. The present invention provides pharmaceutical composition and use as therapeutically active substance thereof.