Patent classifications
C07C233/66
MCT4 inhibitors and uses thereof
Presented herein are MCT4 inhibitors and uses thereof for treating cancer.
SYNTHESIS OF TETRAHYDRONAPHTHALENOLS AND USES THEREOF
Provided herein are compounds and synthetic methods useful for preparing tetrahydronaphthalenol derivatives, and uses of the compounds prepared.
SYNTHESIS OF TETRAHYDRONAPHTHALENOLS AND USES THEREOF
Provided herein are compounds and synthetic methods useful for preparing tetrahydronaphthalenol derivatives, and uses of the compounds prepared.
NOVEL CRYSTALLINE FORMS OF TAMIBAROTENE FOR TREATMENT OF CANCER
Synthesis and characterization of novel tamibarotene forms suitable for pharmaceutical compositions in drug delivery systems to treat human or warm-blooded mammal diseases.
NOVEL CRYSTALLINE FORMS OF TAMIBAROTENE FOR TREATMENT OF CANCER
Synthesis and characterization of novel tamibarotene forms suitable for pharmaceutical compositions in drug delivery systems to treat human or warm-blooded mammal diseases.
Small Molecule Inhibitors Selective for Polo-Like Kinase Proteins
Disclosed are small molecule PLK inhibitors that can target the polo box domain (PBD). Inhibitors can have an atomic mass of about 1000 Da or less and a general structure of
##STR00001##
For instance, the inhibitors can include an alkyl benzamido benzoic acid core structure.
Small Molecule Inhibitors Selective for Polo-Like Kinase Proteins
Disclosed are small molecule PLK inhibitors that can target the polo box domain (PBD). Inhibitors can have an atomic mass of about 1000 Da or less and a general structure of
##STR00001##
For instance, the inhibitors can include an alkyl benzamido benzoic acid core structure.
HYPER-BRANCHED COMPOUNDS, SYNTHESIS AND USES THEREOF
The present invention relates to hyper-branched compounds, a method of synthesizing the hyper-branched compounds and applications of the hyper-branched compounds. The hyper-branched compounds of the present invention include hyper-branched fluorinated compounds, hyper-branched fluorinated graphene and hyper-branched amine functionalized graphene oxide.
HYPER-BRANCHED COMPOUNDS, SYNTHESIS AND USES THEREOF
The present invention relates to hyper-branched compounds, a method of synthesizing the hyper-branched compounds and applications of the hyper-branched compounds. The hyper-branched compounds of the present invention include hyper-branched fluorinated compounds, hyper-branched fluorinated graphene and hyper-branched amine functionalized graphene oxide.
PROCESS FOR DEOXYFLUORINATION OF PHENOLS
The present invention refers to a process for transition-metal-assisted .sup.18F-deoxyfluorination of phenols. The transformation benefits from readily available phenols as starting materials, tolerance of moisture and ambient atmosphere, large substrate scope, and translatability to generate doses appropriate for positron emission tomography (PET) imaging.