The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

##STR00001##

The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##

The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##

Novel friction reducing additives provide friction modification at a lower effective concentration when added to a motor oil base. A friction reducing motor oil composition may include motor oil base and a friction reducing additive having the structure of the general formula (I): ##STR00001##
wherein: R.sub.1 is a straight or branched C.sub.5-C.sub.30 alkyl or alkenyl; R.sub.2 is H, or a straight or branched alkyl of C.sub.1-C.sub.10; R.sub.3 is H, or a straight or branched alkyl of C.sub.1-C.sub.10; P is 0 or C.sub.1; n is C.sub.1-C.sub.5; and m is C.sub.0-C.sub.5.

Novel friction reducing additives provide friction modification at a lower effective concentration when added to a motor oil base. A friction reducing motor oil composition may include motor oil base and a friction reducing additive having the structure of the general formula (I): ##STR00001##
wherein: R.sub.1 is a straight or branched C.sub.5-C.sub.30 alkyl or alkenyl; R.sub.2 is H, or a straight or branched alkyl of C.sub.1-C.sub.10; R.sub.3 is H, or a straight or branched alkyl of C.sub.1-C.sub.10; P is 0 or C.sub.1; n is C.sub.1-C.sub.5; and m is C.sub.0-C.sub.5.

The present invention relates to compounds of formula (I) and to pharmaceutical compositions containing them:

##STR00001##

wherein meanings of the substituents are indicated in the description.

Such compounds for use in the treatment of cancer and other diseases related to altered angiogenesis, such as arthritic pathology, diabetic retinopathy, psoriasis and chronic inflammatory disease, are also within the scope of the present invention.

The present invention relates to compounds of formula (I) and to pharmaceutical compositions containing them:

##STR00001##

wherein meanings of the substituents are indicated in the description.

Such compounds for use in the treatment of cancer and other diseases related to altered angiogenesis, such as arthritic pathology, diabetic retinopathy, psoriasis and chronic inflammatory disease, are also within the scope of the present invention.

Novel friction reducing additives provide friction modification at a lower effective concentration when added to a motor oil base. A friction reducing motor oil composition may include motor oil base and a friction reducing additive having the structure of the general formula (I):

##STR00001##

wherein: R.sub.1 is a straight or branched C.sub.5-C.sub.30 alkyl or alkenyl; R.sub.2 is H, or a straight or branched alkyl of C.sub.1-C.sub.10; R.sub.3 is H, or a straight or branched alkyl of C.sub.1-C.sub.10; P is 0 or C.sub.1; n is C.sub.1-C.sub.5; and m is C.sub.0-C.sub.5.

Novel friction reducing additives provide friction modification at a lower effective concentration when added to a motor oil base. A friction reducing motor oil composition may include motor oil base and a friction reducing additive having the structure of the general formula (I):

##STR00001##

wherein: R.sub.1 is a straight or branched C.sub.5-C.sub.30 alkyl or alkenyl; R.sub.2 is H, or a straight or branched alkyl of C.sub.1-C.sub.10; R.sub.3 is H, or a straight or branched alkyl of C.sub.1-C.sub.10; P is 0 or C.sub.1; n is C.sub.1-C.sub.5; and m is C.sub.0-C.sub.5.

The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

##STR00001##