A convenient method for converting oximes into enamides is disclosed. The process produces enamides without the concomitant production of a large volume of metallic waste.

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The enamides are useful precursors to amides and amines.

The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

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The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

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The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

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The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

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The present invention provides compounds of formula (I), and pharmaceutical compositions thereof. ##STR00001##

The invention relates to novel therapeutic compounds, more in particular to biologically active analogs and uses thereof as medicament, for instance for the treatment of atrial fibrillation. Provided is a compound of the general formula (formula I) wherein R.sub.1 is H or a saturated or unsaturated aliphatic moiety comprising 1 to 8 C-atoms; and X is selected from the group consisting of moieties X.sub.1, X.sub.2, X.sub.3, X.sub.4, X.sub.5 and X.sub.6. Exemplary uses include the prevention or therapeutic treatment of a HSF1-mediated disease. ##STR00001##

The invention relates to novel therapeutic compounds, more in particular to biologically active analogs and uses thereof as medicament, for instance for the treatment of atrial fibrillation. Provided is a compound of the general formula (formula I) wherein R.sub.1 is H or a saturated or unsaturated aliphatic moiety comprising 1 to 8 C-atoms; and X is selected from the group consisting of moieties X.sub.1, X.sub.2, X.sub.3, X.sub.4, X.sub.5 and X.sub.6. Exemplary uses include the prevention or therapeutic treatment of a HSF1-mediated disease. ##STR00001##

The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

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The present invention provides compounds of formula (I), and pharmaceutical compositions thereof.

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