Patent classifications
C07C237/32
Compounds, compositions and methods for treating tumors
Disclosed herein are compounds, compositions and methods for treating tumors, particularly tumors that metastasize, via inhibiting tumor cells-induced platelet aggregation. The compound of the present disclosure has the formula (I), ##STR00001##
wherein, n is 2 or 3.
Compounds, compositions and methods for treating tumors
Disclosed herein are compounds, compositions and methods for treating tumors, particularly tumors that metastasize, via inhibiting tumor cells-induced platelet aggregation. The compound of the present disclosure has the formula (I), ##STR00001##
wherein, n is 2 or 3.
Process for the Preparation of Intermediates Useful in the Preparation of Non-ionic Contrast Agents
The invention relates to a process for the preparation of one or more intermediate chemical compounds useful in the preparation of non-ionic contrast agents wherein the process is carried out continuously using one or more flow procedures.
Process for the Preparation of Intermediates Useful in the Preparation of Non-ionic Contrast Agents
The invention relates to a process for the preparation of one or more intermediate chemical compounds useful in the preparation of non-ionic contrast agents wherein the process is carried out continuously using one or more flow procedures.
PPAR AGONISTS
Provided herein are compounds and compositions useful in increasing PPAR activity. The compounds and compositions provided herein are useful for the treatment of PPAR related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).
PPAR AGONISTS
Provided herein are compounds and compositions useful in increasing PPAR activity. The compounds and compositions provided herein are useful for the treatment of PPAR related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).
Affinity medicant conjugate
In an embodiment of the invention, a composition for treating a cell population comprises an Affinity Medicant Conjugate (AMC). The medicant moiety can be a toxin including an acylfulvene or a drug moiety. The affinity moiety can be an antibody, a binding protein, a steroid, a lipid, a growth factor, a protein, a peptide or non peptidic. The affinity moiety can be covalently bound to the medicant via a linker. Novel linkers that can be directed to cysteine, arginine or lysine residues based on solution pH allow greater flexibility in preserving and/or generating specific epitopes in the AMC.
UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN
UV-absorbing compounds are provided that have at least one reactive hydrogen. These compounds have structures:
##STR00001##
wherein the generic notations have meanings as described herein. Also provided are formulations comprising a UV-absorbing compounds.
UV-ABSORBING COMPOUNDS WITH AT LEAST ONE REACTIVE HYDROGEN
UV-absorbing compounds are provided that have at least one reactive hydrogen. These compounds have structures:
##STR00001##
wherein the generic notations have meanings as described herein. Also provided are formulations comprising a UV-absorbing compounds.
PPAR agonists
Provided herein are compounds and compositions useful in increasing PPAR activity. The compounds and compositions provided herein are useful for the treatment of PPAR related diseases (e.g., muscular diseases, vascular disease, demyelinating disease, and metabolic diseases).