C07C251/30

NOVEL COMPOUND, CORE-SHELL DYE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, AND COLOR FILTER

A compound represented by specific chemical formula, a core including the same, and core-shell dye including a shell surrounding the core, a photosensitive resin composition including the same, and a color filter manufactured using the photosensitive resin composition are disclosed.

MIXED ORGANIC-INORGANIC PEROVSKITE FORMULATIONS

A formulation for use in the preferential formation of thin films of a perovskite material AMX.sub.3 with a certain required crystalline structure, wherein said formulation comprises two or more compounds which between them comprise one or more first organic cations A; one or more metal cations M; one or more second cations A; one or more first anions X and one or more second anions X.

MIXED ORGANIC-INORGANIC PEROVSKITE FORMULATIONS

A formulation for use in the preferential formation of thin films of a perovskite material AMX.sub.3 with a certain required crystalline structure, wherein said formulation comprises two or more compounds which between them comprise one or more first organic cations A; one or more metal cations M; one or more second cations A; one or more first anions X and one or more second anions X.

Acid-resistant base and/or radical generator, and curable resin composition containing said base and/or radical generator

The present invention relates to a compound represented by the general formula (A), a base- and/or radical-generating agent comprising the compound, and so on. ##STR00001##
In the formula, four pieces of R.sup.1 each independently represents a hydrogen atom or a fluorine atom; four pieces of R.sup.2 each independently represent a fluorine atom or a trifluoromethyl group; R.sup.3, R.sup.6, R.sup.7 and R.sup.10 each independently represent a hydrogen atom or an alkyl group having 1 to 12 carbon atoms; R.sup.4 and R.sup.5 each independently represent a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, or R.sup.4 and R.sup.5 are bonded to each other to represent an alkylene group having 2 to 4 carbon atoms; and R.sup.8 and R.sup.9 each independently represent a hydrogen atom, an alkyl group having 1 to 12 carbon atoms, or an aryl group having 6 to 14 carbon atoms and optionally having a substituent selected from the group consisting of an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, an alkylthio group having 1 to 6 carbon atoms, a dialkylamino group having 2 to 12 carbon atoms, a halogen atom, and a nitro group, or R.sup.8 and R.sup.9 are bonded to each other to represent an alkylene group having 2 to 4 carbon atoms; provided that two or three of the eight groups R.sup.3 to R.sup.10 are each a hydrogen atom, and, in a case where two of the eight groups are each a hydrogen atom, then three to six of the remaining groups are each an alkyl group having 1 to 12 carbon atoms, and, in a case where three of the eight groups are each a hydrogen atom, then four or five of the remaining groups are each an alkyl group having 1 to 12 carbon atoms.

Acid-resistant base and/or radical generator, and curable resin composition containing said base and/or radical generator

The present invention relates to a compound represented by the general formula (A), a base- and/or radical-generating agent comprising the compound, and so on. ##STR00001##
In the formula, four pieces of R.sup.1 each independently represents a hydrogen atom or a fluorine atom; four pieces of R.sup.2 each independently represent a fluorine atom or a trifluoromethyl group; R.sup.3, R.sup.6, R.sup.7 and R.sup.10 each independently represent a hydrogen atom or an alkyl group having 1 to 12 carbon atoms; R.sup.4 and R.sup.5 each independently represent a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, or R.sup.4 and R.sup.5 are bonded to each other to represent an alkylene group having 2 to 4 carbon atoms; and R.sup.8 and R.sup.9 each independently represent a hydrogen atom, an alkyl group having 1 to 12 carbon atoms, or an aryl group having 6 to 14 carbon atoms and optionally having a substituent selected from the group consisting of an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, an alkylthio group having 1 to 6 carbon atoms, a dialkylamino group having 2 to 12 carbon atoms, a halogen atom, and a nitro group, or R.sup.8 and R.sup.9 are bonded to each other to represent an alkylene group having 2 to 4 carbon atoms; provided that two or three of the eight groups R.sup.3 to R.sup.10 are each a hydrogen atom, and, in a case where two of the eight groups are each a hydrogen atom, then three to six of the remaining groups are each an alkyl group having 1 to 12 carbon atoms, and, in a case where three of the eight groups are each a hydrogen atom, then four or five of the remaining groups are each an alkyl group having 1 to 12 carbon atoms.

COMPOSITION AND METHODS FOR MEASURING ION CHANNEL ACTIVITY IN A CELL
20190187155 · 2019-06-20 ·

Compositions and methods for detecting the activity of an ion channel in a cell are described. The methods include providing a loading buffer solution to the cell, where the loading buffer includes a thallium ion indicator and optionally chloride ions, and providing a stimulus buffer that includes thallium ions to the cell. Providing the stimulus buffer can cause thallium ion influx into or efflux out of the cell through the ion channel. After providing the stimulus buffer, a change in at least one optical property of the thallium ion indicator is detected in response to thallium influx or efflux, thereby detecting the activity of the ion channel.

FLUOROGENIC SENSORS FOR DETECTING ANTIGENS

Provided herein are fluorogenic sensors which can be used to detect targets (e.g., antigens). In general, the fluorogenic sensors provided herein comprise a protein (e.g., antibody, nanobody, mini-protein) and a fluorogenic small molecule conjugated to the target-binding domain (e.g., antigen-binding domain) of the protein. Upon binding of the protein to said target (e.g., antigen), the fluorogenic small molecule may increase or decrease in fluorescence or exhibit a change in fluorescence lifetime (i.e., turn on), thereby indicating the presence of the target (e.g., antigen).

FLUOROGENIC SENSORS FOR DETECTING ANTIGENS

Provided herein are fluorogenic sensors which can be used to detect targets (e.g., antigens). In general, the fluorogenic sensors provided herein comprise a protein (e.g., antibody, nanobody, mini-protein) and a fluorogenic small molecule conjugated to the target-binding domain (e.g., antigen-binding domain) of the protein. Upon binding of the protein to said target (e.g., antigen), the fluorogenic small molecule may increase or decrease in fluorescence or exhibit a change in fluorescence lifetime (i.e., turn on), thereby indicating the presence of the target (e.g., antigen).