Patent classifications
C07C251/86
Analogs of Nitrofuran Antibiotics to Combat Resistance
Novel compounds and methods of killing or inhibiting the growth of bacteria.
Analogs of Nitrofuran Antibiotics to Combat Resistance
Novel compounds and methods of killing or inhibiting the growth of bacteria.
ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS
The present invention provides a compound having the structure:
##STR00001##
and use of the compound for inhibiting the growth of or killing
DRUG-INDUCED ACTIVATION OF THE REELIN SIGNALING SYSTEM
Disclosed herein are compounds for activating the Reelin signaling system for the treatment of neurological disorders Further provided are compounds and methods for activating a lipoprotein receptor, such as ApoER 2 or VLDLR.
Alkoxy compounds for disease treatment
The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.
Alkoxy compounds for disease treatment
The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.
ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS
The present invention provides a compound having the structure:
##STR00001##
ANTI-FUNGALS TARGETING THE SYNTHESIS OF FUNGAL SHINGOLIPIDS
The present invention provides a compound having the structure:
##STR00001##
Method of modulating ribonucleotide reductase
A method of modulating ribonucleotide reductase activity in a neoplastic cell includes administering to the cell an amount of a triazole or an oxadiazole ribonucleotide reductase modulator (RRmod), the amount being effective to inhibit neoplastic cell growth.
Anti-fungals targeting the synthesis of fungal shingolipids
The present invention provides a compound having the structure: ##STR00001##