The invention relates to novel, optionally deuterated compounds of Formula (I)

##STR00001##

and their use as medicament.

An electrolyte including one or more nitrile benzoquinone compounds, and the nitrile benzoquinone compound is selected from the group consisting of the compounds represented by formula I, formula II, and formula III: ##STR00001##
The substituents R.sub.1 to R.sub.9 are each independently selected from the group consisting of hydrogen, a C.sub.2 to C.sub.12 ether group, a C.sub.1 to C.sub.12 alkoxy group, halogen, a C.sub.1 to C.sub.12 alkyl group, a C.sub.2 to C.sub.12 alkenyl group, a C.sub.2 to C.sub.12 alkynyl group, and a C.sub.6 to C.sub.26 aryl group. The electrolyte can form a stable protective film on a cathode, thereby increasing the cycle capacity retention rate and high temperature storage performance of an electrochemical device.

An electrolyte including one or more nitrile benzoquinone compounds, and the nitrile benzoquinone compound is selected from the group consisting of the compounds represented by formula I, formula II, and formula III: ##STR00001##
The substituents R.sub.1 to R.sub.9 are each independently selected from the group consisting of hydrogen, a C.sub.2 to C.sub.12 ether group, a C.sub.1 to C.sub.12 alkoxy group, halogen, a C.sub.1 to C.sub.12 alkyl group, a C.sub.2 to C.sub.12 alkenyl group, a C.sub.2 to C.sub.12 alkynyl group, and a C.sub.6 to C.sub.26 aryl group. The electrolyte can form a stable protective film on a cathode, thereby increasing the cycle capacity retention rate and high temperature storage performance of an electrochemical device.

An electrochemical device includes a positive electrode plate, a negative electrode plate and an electrolyte, where the positive electrode plate includes a positive electrode active material layer, and the negative electrode plate includes a negative electrode active material layer. Observed along a thickness direction of the electrochemical device, in a width direction of the negative electrode plate, the negative electrode active material layer includes two protruding regions not overlapping with the positive electrode active material layer on two sides, and a width M mm of the protruding region is 0.5 mm to 2 mm. The electrolyte includes a polynitrile compound, and the polynitrile compound includes a compound represented by formula I-A. Based on a mass of the electrolyte, a mass percentage N % of the polynitrile compound is 0.01% to 8%. 0.01MN<10.

An electrochemical device includes a positive electrode plate, a negative electrode plate and an electrolyte, where the positive electrode plate includes a positive electrode active material layer, and the negative electrode plate includes a negative electrode active material layer. Observed along a thickness direction of the electrochemical device, in a width direction of the negative electrode plate, the negative electrode active material layer includes two protruding regions not overlapping with the positive electrode active material layer on two sides, and a width M mm of the protruding region is 0.5 mm to 2 mm. The electrolyte includes a polynitrile compound, and the polynitrile compound includes a compound represented by formula I-A. Based on a mass of the electrolyte, a mass percentage N % of the polynitrile compound is 0.01% to 8%. 0.01MN<10.

Compounds of formula (I) have antibacterial activity:

##STR00001##

wherein R represents hydrogen or 1, 2 or 3 optional substituents; W is C(R.sub.1) or N; R.sub.1 is hydrogen or an optional substituent and R.sub.2 is hydrogen, methyl, or fluorine; or R.sub.1 and R.sub.2 taken together are CH.sub.2, CH.sub.2CH.sub.2, O, or, in either orientation, OCH.sub.2 or OCH.sub.2CH.sub.2; R.sub.3 is a radical of formula -(Alk.sup.1).sub.m-(Z).sub.p-(Alk.sup.2).sub.n-Q wherein m, p and n are independently 0 or 1, provided that at least one of m, p and n is 1, Z is O, S, S(O), S(O.sub.2), NH, N(CH.sub.3), N(CH.sub.2CH.sub.3), C(O), O(CO), C(O)O, or an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted divalent bicyclic heterocyclic radical having 5 to 10 ring atoms; Alk.sup.1 and Alk.sup.2 are optionally substituted C.sub.1-C.sub.6 alkylene, C.sub.2-C.sub.6 alkenylene, or C.sub.2-C.sub.6 alkynylene radicals, which may optionally terminate with or be interrupted by O, S, S(O), S(O.sub.2), NH, N(CH.sub.3), or N(CH.sub.2CH.sub.3); and Q is hydrogen, halogen, nitrile, or hydroxyl or an optionally substituted monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted bicyclic heterocyclic radical having 5 to 10 ring atoms.

Compounds of formula (I) have antibacterial activity:

##STR00001##

wherein R represents hydrogen or 1, 2 or 3 optional substituents; W is C(R.sub.1) or N; R.sub.1 is hydrogen or an optional substituent and R.sub.2 is hydrogen, methyl, or fluorine; or R.sub.1 and R.sub.2 taken together are CH.sub.2, CH.sub.2CH.sub.2, O, or, in either orientation, OCH.sub.2 or OCH.sub.2CH.sub.2; R.sub.3 is a radical of formula -(Alk.sup.1).sub.m-(Z).sub.p-(Alk.sup.2).sub.n-Q wherein m, p and n are independently 0 or 1, provided that at least one of m, p and n is 1, Z is O, S, S(O), S(O.sub.2), NH, N(CH.sub.3), N(CH.sub.2CH.sub.3), C(O), O(CO), C(O)O, or an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted divalent bicyclic heterocyclic radical having 5 to 10 ring atoms; Alk.sup.1 and Alk.sup.2 are optionally substituted C.sub.1-C.sub.6 alkylene, C.sub.2-C.sub.6 alkenylene, or C.sub.2-C.sub.6 alkynylene radicals, which may optionally terminate with or be interrupted by O, S, S(O), S(O.sub.2), NH, N(CH.sub.3), or N(CH.sub.2CH.sub.3); and Q is hydrogen, halogen, nitrile, or hydroxyl or an optionally substituted monocyclic carbocyclic or heterocyclic radical having 3 to 6 ring atoms; or an optionally substituted bicyclic heterocyclic radical having 5 to 10 ring atoms.

The present invention relates to new classes of odorous 3-(2-methylenealkoxy)alkanenitrile derivatives of formula (I) which are useful as fragrance or flavor materials in particular in providing dry, woody, dusty, earthy, and/or patchouli notes together with optional coriander, aldehydic, citrus, mandarin, pear, cinnamon, and/or petal floral-like notes to perfume, aroma or deodorizing/masking compositions. ##STR00001##

The present invention relates to new classes of odorous 3-(2-methylenealkoxy)alkanenitrile derivatives of formula (I) which are useful as fragrance or flavor materials in particular in providing dry, woody, dusty, earthy, and/or patchouli notes together with optional coriander, aldehydic, citrus, mandarin, pear, cinnamon, and/or petal floral-like notes to perfume, aroma or deodorizing/masking compositions. ##STR00001##