Patent classifications
C07C255/46
Chemoselective methylene hydroxylation in aromatic molecules
A chemoselective and reactive Mn(CF.sub.3-PDP) catalyst system that enables for the first time the strategic advantages of late-stage aliphatic CH hydroxylation to be leveraged in aromatic compounds. This discovery will benefit small molecule therapeutics by enabling the rapid diversification of aromatic drugs and natural products and identification of their metabolites.
PRODUCTION METHOD FOR 1,4-CYCLOHEXANEDICARBOXYLIC ACID DERIVATIVE, 1,4-DICYANOCYCLOHEXANE AND 1,4-BIS(AMINOMETHYL)CYCLOHEXANE
A production method for producing a 1,4-cyclohexanedicarboxylic acid derivative, involves subjecting an aqueous ammonia solution of 1,4-cyclohexanedicarboxylic acid to heat concentration, thereby precipitating a 1,4-cyclohexanedicarboxylic acid derivative as a crystal.
PRODUCTION METHOD FOR 1,4-CYCLOHEXANEDICARBOXYLIC ACID DERIVATIVE, 1,4-DICYANOCYCLOHEXANE AND 1,4-BIS(AMINOMETHYL)CYCLOHEXANE
A production method for producing a 1,4-cyclohexanedicarboxylic acid derivative, involves subjecting an aqueous ammonia solution of 1,4-cyclohexanedicarboxylic acid to heat concentration, thereby precipitating a 1,4-cyclohexanedicarboxylic acid derivative as a crystal.
Method for producing 1,4-dicyanocyclohexane, 1,4-bis(aminomethyl)cyclohexane and 1,4-cyclohexanedicarboxylic acid
A method for producing 1,4-dicyanocyclohexane, having a step of obtaining 1,4-dicyanocyclohexane by subjecting a heated concentrate of an aqueous ammonia solution of 1,4-cyclohexanedicarboxylic acid to a cyanation reaction.
Method for producing 1,4-dicyanocyclohexane, 1,4-bis(aminomethyl)cyclohexane and 1,4-cyclohexanedicarboxylic acid
A method for producing 1,4-dicyanocyclohexane, having a step of obtaining 1,4-dicyanocyclohexane by subjecting a heated concentrate of an aqueous ammonia solution of 1,4-cyclohexanedicarboxylic acid to a cyanation reaction.
Method for producing 1,4-dicyanocyclohexane, 1,4-bis(aminomethyl)cyclohexane and 1,4-cyclohexanedicarboxylic acid
A method for producing 1,4-dicyanocyclohexane, having a step of obtaining 1,4-dicyanocyclohexane by subjecting a heated concentrate of an aqueous ammonia solution of 1,4-cyclohexanedicarboxylic acid to a cyanation reaction.
PRODUCTION METHOD FOR CYCLOHEXANEDICARBOXYLIC ACID COMPOUND, DICYANOCYCLOHEXANE COMPOUND AND BIS(AMINOMETHYL)CYCLOHEXANE COMPOUND
A production method for a cyclohexanedicarboxylic acid compound, having a step of obtaining a cyclohexanedicarboxylic acid compound or an aqueous ammonia solution of a cyclohexanedicarboxylic acid compound by bringing a phthalic acid compound in an aqueous ammonia solution into contact with hydrogen in the presence of a fixed bed catalyst in a reactor.
PRODUCTION METHOD FOR CYCLOHEXANEDICARBOXYLIC ACID COMPOUND, DICYANOCYCLOHEXANE COMPOUND AND BIS(AMINOMETHYL)CYCLOHEXANE COMPOUND
A production method for a cyclohexanedicarboxylic acid compound, having a step of obtaining a cyclohexanedicarboxylic acid compound or an aqueous ammonia solution of a cyclohexanedicarboxylic acid compound by bringing a phthalic acid compound in an aqueous ammonia solution into contact with hydrogen in the presence of a fixed bed catalyst in a reactor.
PHENYL CYCLOHEXANONE DERIVATIVES AND METHODS OF MAKING AND USING THEM
Phenyl cyclohexanone based active agents, pharmaceutical preparations containing such active agents, methods of modifying cellular activity by contacting cells with such active agents, and methods of treating various conditions by administering such active agents to a patient are described.
PHENYL CYCLOHEXANONE DERIVATIVES AND METHODS OF MAKING AND USING THEM
Phenyl cyclohexanone based active agents, pharmaceutical preparations containing such active agents, methods of modifying cellular activity by contacting cells with such active agents, and methods of treating various conditions by administering such active agents to a patient are described.