Provided herein, inter alia, are compounds and methods useful for modulating the translational effects of eIF2α phosphorylation, the Integrated Stress Response (ISR), and the unfolded protein response (UPR); for treating diseases; for increasing protein production, and for improving long-term memory.

A raw material for forming a thin film, comprising a compound represented by General Formula (1) below. ##STR00001##
(in the formula, R.sup.1 represents a linear or branched alkyl group having 1 to 5 carbon atoms, R.sup.2 represents hydrogen or a linear or branched alkyl group having 1 to 5 carbon atoms, R.sup.3 and R.sup.4 each independently represent a linear or branched alkyl group having 1 to 5 carbon atoms, A represents an alkanediyl group having 1 to 4 carbon atoms and M represents copper, iron, nickel, cobalt or manganese.).

This disclosure relates to aryl amidines of Formula I and their use as fungicides.

##STR00001##

This disclosure relates to aryl amidines of Formula I and their use as fungicides.

##STR00001##

This disclosure relates to aryl amidines of Formula I and their use as fungicides.

##STR00001##

The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in .sup.18F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs. In some embodiments, methods and compositions for assessing perfusion and innervation mismatch in a portion of a subject are provided.

The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in .sup.18F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs. In some embodiments, methods and compositions for assessing perfusion and innervation mismatch in a portion of a subject are provided.

Disclosed are ROS-sensitive NOS inhibitors, as well as methods of making and using the same.

Disclosed are ROS-sensitive NOS inhibitors, as well as methods of making and using the same.

This invention relates to compounds that inhibit creatine transport and/or creatine kinase, pharmaceutical compositions including such compounds, and methods of utilizing such compounds and compositions for the treatment of cancer.