C07C275/40

ANTIBACTERIAL HYDROPHILIC COMPOUND AND USE THEREOF

The present disclosure provides an antibacterial hydrophilic compound. The antibacterial hydrophilic compound may react, induced by light through a hydrogen abstraction group in the structural formula thereof, with a CH group and thus bind to a surface of a material having the CH group (for example, chemical fibers such as polyester, chinlon, and the like; plastics, rubbers, and other similar materials), which can impart a durable antibacterial activity and hydrophilicity to the material. The antibacterial hydrophilic compound has a relatively strong binding force to the surface of the material without damaging the mechanical properties of the raw material. The present disclosure also provides a modified material that is modified by the antibacterial hydrophilic compound.

RECORDING MATERIAL AND COMPOUND

An object of the present invention is to provide a recording material or a recording sheet using, as a color-developing agent, a non-phenol-based compound good in color developing performance and the like. A compound represented by the following formula (I) is used as the color-developing agent:

##STR00001##

(wherein X represents CH.sub.2 or the like; R.sup.1 to R.sup.3 each independently represent a hydrogen atom, a halogen atom or the like; n1 and n3 each independently represent any integer of 1 to 5; two groups represented by R.sup.3 adjacent to each other on a benzene ring optionally bond to each other to form an optionally substituted 6-membered ring; and n2 represents any integer of 1 to 4).

INHIBITOR OF INDOLEAMINE-2,3-DIOXYGENASE (IDO)
20200046697 · 2020-02-13 ·

The present disclosure provides compounds of Formula (I). The compounds described herein may be useful in treating a disease associated with IDO, for example, cancer or an infectious disease (e.g., viral or bacterial infectious diseases). Also, provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.

##STR00001##

VINYLARENE DERIVATIVE AND APPLICATION

The present invention relates to a vinylarene deriv. which modulates or inhibits the enzymic activity of indoleamine 2,3-dioxygenase 1 (IDO-1), and the use thereof, and further relates to a vinylarene deriv. and the use thereof. The vinylarene deriv. and its stereoisomer, cis- or trans-isomer, or tautomer thereof and pharmaceutically acceptable salt thereof, has an IDO-1 enzyme inhibitory activity, and is expected to provide brand new therapeutic methods and schemes for related diseases caused by IDO enzymes.

##STR00001##

VINYLARENE DERIVATIVE AND APPLICATION

The present invention relates to a vinylarene deriv. which modulates or inhibits the enzymic activity of indoleamine 2,3-dioxygenase 1 (IDO-1), and the use thereof, and further relates to a vinylarene deriv. and the use thereof. The vinylarene deriv. and its stereoisomer, cis- or trans-isomer, or tautomer thereof and pharmaceutically acceptable salt thereof, has an IDO-1 enzyme inhibitory activity, and is expected to provide brand new therapeutic methods and schemes for related diseases caused by IDO enzymes.

##STR00001##

Bioinspired catalysis using oligourea helical foldamers

The present description provides oligourea catalysts, a polar helical oligomeric strands, and methods for catalyzing reactions with polar helical oligomeric strands and oligourea catalysts. In particular, the invention relates to a polar helical oligomeric strand of at least 4 residues selected from the formula (I) and which can be used as a catalyst.

Bioinspired catalysis using oligourea helical foldamers

The present description provides oligourea catalysts, a polar helical oligomeric strands, and methods for catalyzing reactions with polar helical oligomeric strands and oligourea catalysts. In particular, the invention relates to a polar helical oligomeric strand of at least 4 residues selected from the formula (I) and which can be used as a catalyst.

Heat-sensitive recording material

This heat-sensitive recording material is configured to contain, as a color-developing compound, at least one compound represented by one of formulas (1)-(3): ##STR00001##

Heat-sensitive recording material

This heat-sensitive recording material is configured to contain, as a color-developing compound, at least one compound represented by one of formulas (1)-(3): ##STR00001##

Fluorine atom-containing compound and use thereof

Provided is a fluorine atom-containing compound represented by formula (1) below ##STR00001##
(In the formula, Z represents a predetermined divalent group, each Ar independently represents a predetermined aromatic ring-containing group, and each Ar.sup.F independently represents a predetermined fluorine atom-containing aryl group).