C07C291/04

DEUTERATED COMPOUNDS AND USES THEREOF

An anthraquinone compound of formula I (such as the compounds of formulae II to X) and processes for making the same are provided. Pharmaceutical compositions for use in the treatment of cancer, optionally in combination with an agent capable of reducing the level of oxygenation of a tumour, are also provided. Additionally, an option for combination with chemotherapeutic and radiotherapeutic modalities to enhance overall tumour cell kill is provided. Methods for the detection of cellular hypoxia, both in vivo and in vitro, are additionally provided.

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Rosin-based small molecular weight hydrogelator and its application
20200223789 · 2020-07-16 ·

The present disclosure discloses a rosin-based small molecular weight hydrogelator and an application thereof, and belongs to the fields of supramolecular chemistry, surfactant science and chemical utilization of rosin. The rosin-based small molecular hydrogel of the present disclosure can gel water at a very low concentration, and the critical gelling concentration is only 0.176 wt %. On average, each gelling agent molecule can hold 13,889 water molecules, which exhibits extremely high gel efficiency and the formed small molecular hydrogel also exhibits extremely high stability. This small molecule hydrogel is derived from the natural product rosin and has a mild nature. It can be used in the fields of drug sustained-release, tissue engineering, daily chemicals, medicine and so on. At the same time, the rosin-based small molecular hydrogel 6-dehydroabietylamide amine oxide in the present disclosure can form a stable gel emulsion for most oils, and can be used in many fields such as food, medicine, daily chemicals, tissue engineering, environmental protection, and water pollution control.

N-type thermoelectric conversion layer, thermoelectric conversion element, and composition for forming N-type thermoelectric conversion layer

An object of the present invention is to provide an n-type thermoelectric conversion layer, which has a high power factor and exhibits excellent performance stability, a thermoelectric conversion element including the n-type thermoelectric conversion layer, and a composition for forming an n-type thermoelectric conversion layer used in the n-type thermoelectric conversion layer. The n-type thermoelectric conversion layer of the present invention contains carbon nanotubes and an amine compound which is represented by General Formula (1) or (2) and has a C log P value of 2.0 to 8.2. ##STR00001##

N-type thermoelectric conversion layer, thermoelectric conversion element, and composition for forming N-type thermoelectric conversion layer

An object of the present invention is to provide an n-type thermoelectric conversion layer, which has a high power factor and exhibits excellent performance stability, a thermoelectric conversion element including the n-type thermoelectric conversion layer, and a composition for forming an n-type thermoelectric conversion layer used in the n-type thermoelectric conversion layer. The n-type thermoelectric conversion layer of the present invention contains carbon nanotubes and an amine compound which is represented by General Formula (1) or (2) and has a C log P value of 2.0 to 8.2. ##STR00001##

Branched trialkyl quaternary ammonium compounds

The surfactants which can be produced from the trialkylamine intermediates include the quaternary ammonium compounds of formula: ##STR00001##

Branched trialkyl quaternary ammonium compounds

The surfactants which can be produced from the trialkylamine intermediates include the quaternary ammonium compounds of formula: ##STR00001##

BENZOQUINOLONE INHIBITORS OF VMAT2
20200000794 · 2020-01-02 ·

The present invention relates to new benzoquinolone inhibitors of VMAT2, pharmaceutical compositions thereof, and methods of use thereof.

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BENZOQUINOLONE INHIBITORS OF VMAT2
20200000794 · 2020-01-02 ·

The present invention relates to new benzoquinolone inhibitors of VMAT2, pharmaceutical compositions thereof, and methods of use thereof.

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Dimethyl Farnesyl Amine Oxide And Its Use As Surfactant Or Wetting Agent

Dimethyl amine oxides comprising farnesyl residues are described. These amine oxides are advantageously suited as surfactants or wetting agents.

Dimethyl Farnesyl Amine Oxide And Its Use As Surfactant Or Wetting Agent

Dimethyl amine oxides comprising farnesyl residues are described. These amine oxides are advantageously suited as surfactants or wetting agents.