Patent classifications
C07C303/40
Direct oxidative amination of hydrocarbons
Provided is a process for converting a hydrocarbon comprising at least one C—H bond to a nitrogen-functionalized product. The process comprises contacting a hydrocarbon and (i) an oxidizing electrophile comprising (a) a main group element or transition metal in oxidized form and (b) at least one nitrogen-containing ligand, or (ii) an oxidant and a reduced form of an oxidizing electrophile comprising (a) a main group element or transition metal and (b) at least one nitrogen-containing ligand, in a solvent to provide the nitrogen-functionalized product and an electrophile reduction product. Further provided is an oxidizing composition comprising the oxidizing electrophile with at least one nitrogen-containing ligand and a non-oxidizable liquid.
Sulfamic acid derivatives and processes for their preparation
Here are described processes for the preparation of sulfamic acid derivatives, for instance, halogenated derivatives and their metallic or organic salts. The present document also describes the sulfamic acid derivatives thus produced and to their uses, for instance, in electrolyte compositions for electrochemical applications.
Sulfamic acid derivatives and processes for their preparation
Here are described processes for the preparation of sulfamic acid derivatives, for instance, halogenated derivatives and their metallic or organic salts. The present document also describes the sulfamic acid derivatives thus produced and to their uses, for instance, in electrolyte compositions for electrochemical applications.
Sulfamic acid derivatives and processes for their preparation
Here are described processes for the preparation of sulfamic acid derivatives, for instance, halogenated derivatives and their metallic or organic salts. The present document also describes the sulfamic acid derivatives thus produced and to their uses, for instance, in electrolyte compositions for electrochemical applications.
Polymorphic forms of Belinostat and processes for preparation thereof
The present invention relates to the polymorphic forms of Belinostat. The invention also relates to the process for the preparation of the polymorphic forms of Belinostat. This invention further relates to pharmaceutical composition of said polymorphic forms of Belinostat and use thereof in the treatment of a patient in need thereof.
Polymorphic forms of Belinostat and processes for preparation thereof
The present invention relates to the polymorphic forms of Belinostat. The invention also relates to the process for the preparation of the polymorphic forms of Belinostat. This invention further relates to pharmaceutical composition of said polymorphic forms of Belinostat and use thereof in the treatment of a patient in need thereof.
Polymorphic forms of Belinostat and processes for preparation thereof
The present invention relates to the polymorphic forms of Belinostat. The invention also relates to the process for the preparation of the polymorphic forms of Belinostat. This invention further relates to pharmaceutical composition of said polymorphic forms of Belinostat and use thereof in the treatment of a patient in need thereof.
Synthetic process
- William P. Gallagher ,
- John Ryan Coombs ,
- Carlos A. Guerrero ,
- David Marcoux ,
- Qing Shi ,
- Candice Lee Joe ,
- Sanjeewa Rupasinghe ,
- Jason J. Zhu ,
- Srinivas Kalidindi ,
- Sathasivam Shunmugaraj ,
- Moorthy Kandasamy ,
- Siva Sankar Bondigela ,
- Rajappa Vaidyanathan ,
- Shankar Tulsidas Tendulkar ,
- Sankar Kuppusamy ,
- Francisco González-Bobes
The invention generally relates to a process for preparing compounds, including Compound of Formula (I), useful as key intermediates in the preparation of compounds having RORγt antagonist properties. ##STR00001##
Synthetic process
- William P. Gallagher ,
- John Ryan Coombs ,
- Carlos A. Guerrero ,
- David Marcoux ,
- Qing Shi ,
- Candice Lee Joe ,
- Sanjeewa Rupasinghe ,
- Jason J. Zhu ,
- Srinivas Kalidindi ,
- Sathasivam Shunmugaraj ,
- Moorthy Kandasamy ,
- Siva Sankar Bondigela ,
- Rajappa Vaidyanathan ,
- Shankar Tulsidas Tendulkar ,
- Sankar Kuppusamy ,
- Francisco González-Bobes
The invention generally relates to a process for preparing compounds, including Compound of Formula (I), useful as key intermediates in the preparation of compounds having RORγt antagonist properties. ##STR00001##
METHOD FOR PRODUCING DICHLORO ADDITION PRODUCT OF ALIPHATIC OLEFIN BY PHOTOCATALYSIS UNDER VISIBLE LIGHT
The invention provides a method for producing a dichloro addition product of an aliphatic olefin by photocatalysis under visible light. The method includes reacting an aliphatic olefin as a substrate with hydrochloric acid as a chlorine source in an organic solvent under visible light irradiation in the presence of copper chloride with visible light absorption ability as a catalyst, to obtain the dichloro addition product of the aliphatic olefin, wherein the reaction is carried out under an oxygen-containing atmosphere, the aliphatic olefin comprises a carbon-carbon double bond and a C9-C15 aliphatic chain connected to the carbon-carbon double bond by a covalent bond. In the invention, visible light is used to provide the energy and a transition metal chloride with visible light absorption ability is used to undergo light-induced electron transfer from chloride with a reaction substrate, thereby initiating an addition reaction to obtain a dichloro addition product.