The present disclosure relates to a compound of formula (Ia), (Ib), (IIa), and (IIb):

##STR00001## ##STR00002##

which are useful in the treatment of a Retroviridae viral infection including an infection caused by the HIV virus.

The present disclosure relates to a compound of formula (Ia), (Ib), (IIa), and (IIb):

##STR00001## ##STR00002##

which are useful in the treatment of a Retroviridae viral infection including an infection caused by the HIV virus.

Systems and processes for hydrotreating, splitting, and extracting a gasoil feed to produce a saturate-rich feedstock for olefin pyrolysis are provided. A gasoil feed is provided to a hydrotreating section to produce an ultralow sulfur distillate (ULSD) stream. The ULSD stream is provided to a splitter section to produce a light distillate stream and a heavy bottom stream. The light distillate stream is provided to an extraction section to produce an aromatic-rich extract phase and a saturate-rich raffinate phase. The raffinate phase is mixed with the heavy bottom stream to produce an olefin pyrolysis feedstock having a reduced BMCI as compared to the gasoil feed stream and the ULSD stream.

Provided herein are a use of thioether compounds of formula I as nitrification inhibitors, and agricultural mixtures and compositions including the thioether compounds.

Provided herein are a use of thioether compounds of formula I as nitrification inhibitors, and agricultural mixtures and compositions including the thioether compounds.

The present disclosure relates to a compound of formula (Ia), (Ib), (IIa), and (IIb): ##STR00001## ##STR00002##
which are useful in the treatment of a Retroviridae viral infection including an infection caused by the HIV virus.

The present disclosure relates to a compound of formula (Ia), (Ib), (IIa), and (IIb): ##STR00001## ##STR00002##
which are useful in the treatment of a Retroviridae viral infection including an infection caused by the HIV virus.

K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.

K-Ras is the most frequently mutated oncogene in human cancer. Disclosed herein are compositions and methods for modulating K-Ras and treating cancer.