Alkylamine-substituted perthiocarbamates capable of controllable release of hydropersulfides (RSSH) and carbonyl sulfide (COS) and their use in treating or preventing ischemia-reperfusion injury are described.

Alkylamine-substituted perthiocarbamates capable of controllable release of hydropersulfides (RSSH) and carbonyl sulfide (COS) and their use in treating or preventing ischemia-reperfusion injury are described.

An embodiment relates to a polymeric composition for a polythiourethane-based optical material, wherein the polymeric composition, comprising a particular additive, may appropriately adjust the reactivity of an isocyanate such that viscosity is maintained low for a predetermined period of time, and thus is capable of preparing a high-quality polythiourethane-based optical material, without a complicated purification process. Moreover, a polythiourethane-based optical material according to an embodiment has not only a uniform refractive index, but also a low yellow index, and thus may be used as a variety of plastic optical lenses, such as an eyeglass lens or a camera lens and the like.

An embodiment relates to a polymeric composition for a polythiourethane-based optical material, wherein the polymeric composition, comprising a particular additive, may appropriately adjust the reactivity of an isocyanate such that viscosity is maintained low for a predetermined period of time, and thus is capable of preparing a high-quality polythiourethane-based optical material, without a complicated purification process. Moreover, a polythiourethane-based optical material according to an embodiment has not only a uniform refractive index, but also a low yellow index, and thus may be used as a variety of plastic optical lenses, such as an eyeglass lens or a camera lens and the like.

The present invention discloses methods for synthesizing asymmetrical sulfide compounds and asymmetrical ether compounds from a variety of ether, sulfide, alcohol, and thiol reactants that are contacted in the presence of a suitable catalyst. Conversions of the limiting reactant to the desired asymmetrical sulfide or asymmetrical ether compound generally exceed 50%.

The present invention discloses methods for synthesizing asymmetrical sulfide compounds and asymmetrical ether compounds from a variety of ether, sulfide, alcohol, and thiol reactants that are contacted in the presence of a suitable catalyst. Conversions of the limiting reactant to the desired asymmetrical sulfide or asymmetrical ether compound generally exceed 50%.

The present invention discloses methods for synthesizing asymmetrical sulfide compounds and asymmetrical ether compounds from a variety of ether, sulfide, alcohol, and thiol reactants that are contacted in the presence of a suitable catalyst. Conversions of the limiting reactant to the desired asymmetrical sulfide or asymmetrical ether compound generally exceed 50%.

A polythiol composition according to exemplary examples includes a tetrafunctional polythiol compound, and a sub-polythiol compound including a compound represented by C.sub.13H.sub.28S.sub.9 and a compound represented by C.sub.15H.sub.32S.sub.10. A ratio of the sub-polythiol compound measured through a high performance liquid chromatography (HPLC) analysis graph is 1% to 5%. By adjusting the content of the sub-polythiol compound, it is possible to manufacture an optical product having excellent transmittance and optical properties.

The present application relates to mass spectrometry methods for use in identifying proteins or other biomolecules which are bound irreversibly by test compounds.

The present application relates to mass spectrometry methods for use in identifying proteins or other biomolecules which are bound irreversibly by test compounds.