The invention relates to a method for obtaining an amine from a composition by means of distillation and a composition obtainable by that method. The invention also relates to a method for the production of an isocyanate from the composition obtainable.

Disclosed is a blend prepared by mixing a prepolymer and a vinyl monomer, wherein the prepolymer is prepared by a condensation reaction between a first compound represented by the formula ArH, where Ar comprises (a) a crosslinkable moiety at one end, (b) a moiety selected from the group consisting of O, S, COO, CO, COS, SO.sub.2, and NH, and (c) one or two repeating units selected from the group consisting of: ##STR00001##
where A is carbon or nitrogen, and X is hydrogen or halogen; and a second compound consisting of an aromatic moiety. Additionally disclosed is a polymer sheet that is a crosslinked product composed of the blend.

Compounds of the formula 1

##STR00001##

wherein, R is hydrogen, alkyl or substituted alkyl, aryl or substituted aryl, are useful intermediates in the synthesis of fragrance ingredients such as Ambrox 2

##STR00002##

Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (I SR) and for treating related diseases, disorders, and conditions.

A multi-tail type ionizable lipid, a preparation method therefor and the use thereof are disclosed. The structural formula of the multi-tail type ionizable lipid of the present invention is as follows,

##STR00001##

wherein R.sub.1 and R.sub.2 are the same or different, and each is hydrogen or an alkyl chain or an alkyl ring consisting of 1 to 6 carbons, or R.sub.1 and R.sub.2 together form a nitrogen-containing alkyl ring; L.sub.1 and L.sub.2 are the same or different, and each is an alkyl chain or an unsaturated hydrocarbyl group consisting of 1 to 6 carbons in length; and R is an alkyl group, an alkyl ring, an unsaturated hydrocarbyl group, or a heterohydrocarbyl group; and n=1 to 6, m1=1 to 15, m2=1 to 15, and x=0 to 5.