There is provided a novel agent for controlling harmful arthropods or nematodes that are parasites and hygienic pests for animals. An ecto- or endo-parasiticide for mammals or the like comprising as active ingredient, one or more selected from substituted benzamide compounds of formula (1) or salts thereof: ##STR00001##
wherein A.sup.1 is CX.sup.3 or nitrogen atom, etc., A.sup.2 and A.sup.3 are CH, etc., A.sup.4 is CH or nitrogen atom, etc., G is G-2a, etc., W is oxygen atom or sulfur atom, X.sup.1 is halogen atom, trifluoromethyl, etc., X.sup.2 is hydrogen atom, halogen atom, trifluoromethyl, etc., X.sup.3 is hydrogen atom, halogen atom, etc., Y.sup.1 is hydrogen atom, halogen atom, methyl, etc., R.sup.1 is trifluoromethyl, etc., R.sup.2 is E-3a, etc., R.sup.3 is hydrogen atom, etc., p is an integer of 0 to 2.

There is provided a novel agent for controlling harmful arthropods or nematodes that are parasites and hygienic pests for animals. An ecto- or endo-parasiticide for mammals or the like comprising as active ingredient, one or more selected from substituted benzamide compounds of formula (1) or salts thereof: ##STR00001##
wherein A.sup.1 is CX.sup.3 or nitrogen atom, etc., A.sup.2 and A.sup.3 are CH, etc., A.sup.4 is CH or nitrogen atom, etc., G is G-2a, etc., W is oxygen atom or sulfur atom, X.sup.1 is halogen atom, trifluoromethyl, etc., X.sup.2 is hydrogen atom, halogen atom, trifluoromethyl, etc., X.sup.3 is hydrogen atom, halogen atom, etc., Y.sup.1 is hydrogen atom, halogen atom, methyl, etc., R.sup.1 is trifluoromethyl, etc., R.sup.2 is E-3a, etc., R.sup.3 is hydrogen atom, etc., p is an integer of 0 to 2.

The invention relates to the field of preserving the viability of organs or tissues to be transplanted into a recipient in need of such a transplantation. In particular, the invention relates to use of a sigma 1 receptor agonist compound in preservation solutions and preservation solutions comprising a sigma 1 receptor agonist compound.

The invention relates to the field of preserving the viability of organs or tissues to be transplanted into a recipient in need of such a transplantation. In particular, the invention relates to use of a sigma 1 receptor agonist compound in preservation solutions and preservation solutions comprising a sigma 1 receptor agonist compound.

Inhibitors of HBV replication of formula (I) ##STR00001##
including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein X, R.sup.1 to R.sup.7 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.

Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.

Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.