An anti-freezing composition according to an embodiment of the present disclosure includes at least one of a compound represented by Formula 1 and a compound represented by Formula 2. An anti-freezing composition according to another embodiment of the present disclosure includes a peptide consisting of amino acids having different chirality, thereby having an excellent effect of inhibiting ice formation or ice recrystallization.

An anti-freezing composition according to an embodiment of the present disclosure includes at least one of a compound represented by Formula 1 and a compound represented by Formula 2. An anti-freezing composition according to another embodiment of the present disclosure includes a peptide consisting of amino acids having different chirality, thereby having an excellent effect of inhibiting ice formation or ice recrystallization.

The present invention relates to 4-substituted phenylamidine derivatives of the general formula (I), wherein R5-R6, ArA4, D, G, B, Q and an integer m have the meanings as defined in the description. The invention further relates to methods for their preparation and use of said compounds for controlling undesired phytopathogenic microorganisms, and agents for said purpose, comprising said phenylamine derivatives. This invention further relates to a method for controlling undesired phytopathogenic microorganisms by application of said 4-substituted phenylamidine derivatives of general formula (I) to such undesired microorganisms and/or to their habitat, according to the invention.

Disclosed herein are secondary amine compounds that inhibit tRNA synthetase. The compounds of the invention are useful in inhibiting tRNA synthetase in Gram-negative bacteria and are useful in killing Gram-negative bacteria. The secondary amine compounds of the invention are also useful in the treatment of tuberculosis.

Disclosed herein are secondary amine compounds that inhibit tRNA synthetase. The compounds of the invention are useful in inhibiting tRNA synthetase in Gram-negative bacteria and are useful in killing Gram-negative bacteria. The secondary amine compounds of the invention are also useful in the treatment of tuberculosis.

The present invention provides an amphoteric fluorescent substance capable of being attached to biomaterials.

The present invention provides an amphoteric fluorescent substance capable of being attached to biomaterials.

In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: wherein the variables shown in Formula AA can be as defined anywhere herein. Compounds AA are modulators of NLRP1 and/or NLRP3

##STR00001##

In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured: wherein the variables shown in Formula AA can be as defined anywhere herein. Compounds AA are modulators of NLRP1 and/or NLRP3

##STR00001##

The invention relates to compound shown with formula (I) or a pharmaceutically acceptable derivative thereof for use as a novel inhibitor of MDM2 activity.