Patent classifications
C07D209/54
INTERMEDIATE COMPOUNDS AND METHODS
The present invention relates to compounds of (II) and an acceptable salt or hydrate thereof method of making same.
##STR00001##
SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES
Disclosed are compounds of Formula 1, all stereoisomers, N-oxides, and salts thereof,
##STR00001##
wherein G is CONR.sup.5R.sup.6 or selected from
##STR00002## and R.sup.1 through R.sup.18, R.sup.f and G are as defined in the Disclosure.
Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.
SUBSTITUTED HALOALKYL SULFONANILIDE HERBICIDES
Disclosed are compounds of Formula 1, all stereoisomers, N-oxides, and salts thereof,
##STR00001##
wherein G is CONR.sup.5R.sup.6 or selected from
##STR00002## and R.sup.1 through R.sup.18, R.sup.f and G are as defined in the Disclosure.
Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.
SSAO INHIBITORS AND USE THEREOF
The application relates to a compound of Formula (I′) or (I):
##STR00001##
or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, which modulates the activity of SSAO, a pharmaceutical composition comprising a compound of Formula (I′) or (I), and a method of treating or preventing a disease in which SSAO plays a role.
NAMPT MODULATORS
Provided are compounds of Formula (II): or a pharmaceutically acceptable salt thereof, wherein R1, n, and Y1 are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (II), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (II), or a pharmaceutically acceptable salt thereof.
##STR00001##
NAMPT MODULATORS
Provided are compounds of Formula (II): or a pharmaceutically acceptable salt thereof, wherein R1, n, and Y1 are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (II), or a pharmaceutically acceptable salt thereof. Also provided are methods of using a compound of Formula (II), or a pharmaceutically acceptable salt thereof.
##STR00001##
HERBICIDAL COMPOUNDS
The present invention relates to compounds of Formula (I), (I) wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants.
##STR00001##
HERBICIDAL COMPOUNDS
The present invention relates to compounds of Formula (I), (I) wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I), to their use for controlling weeds, in particular in crops of useful plants.
##STR00001##
HDAC6 INHIBITORS AND USES THEREOF
Provided herein are compounds that inhibit HDAC6, a protein whose activity is associated with a variety of diseases (e.g., cancer, neurological disorders). Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating HDAC6-related diseases and disorders (e.g., Alzheimer's disease, cancer) with the compounds in a subject, by administering the compounds and/or compositions described herein.
METHODS USING HDAC11 INHIBITORS
The present invention provides methods and uses of inhibitors of histone deacetylase 11 (HDAC11) in the treatment of diseases and/or disorders, such as, for example, cell proliferative diseases.